DYRK2 Products
(Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
Categories
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008].
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Featured DYRK2 Categories
DYRK2 Antibodies
High quality antibodies with extensive validation data.
DYRK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DYRK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (8)
- (3)
Cat. No.
ABIN391770
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN657991
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN563627
Quantity
100 μg
Datasheet
Datasheet
Recommended DYRK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570574
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352206
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352208
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our DYRK2 products
: "Impairment of DYRK2 augments stem-like traits by promoting KLF4 expression in breast cancer." in: Oncogene, Vol. 36, Issue 13, pp. 1862-1872, (2017) (PubMed).: "Dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) as a novel marker in T1 high-grade and T2 bladder cancer patients receiving neoadjuvant chemotherapy." in: BMC urology, Vol. 15, pp. 53, (2015) (PubMed).
: "The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143376, (2015) (PubMed).
: "Downregulation of DYRK2 can be a predictor of recurrence in early stage breast cancer." in: Tumour biology, Vol. 35, Issue 11, pp. 11021-5, (2014) (PubMed).
: "DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 859-72, (2012) (PubMed).
: "Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways." in: Journal of molecular cell biology, Vol. 4, Issue 5, pp. 316-30, (2012) (PubMed).
: "Expression of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 2 (DYRK2) can be a favorable prognostic marker in pulmonary adenocarcinoma." in: The Journal of thoracic and cardiovascular surgery, Vol. 138, Issue 6, pp. 1303-8, (2009) (PubMed).
: "DYRK2 expression may be a predictive marker for chemotherapy in non-small cell lung cancer." in: Anticancer research, Vol. 29, Issue 7, pp. 2753-7, (2009) (PubMed).
: "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." in: Cell, Vol. 133, Issue 3, pp. 537-48, (2008) (PubMed).
: "DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage." in: Molecular cell, Vol. 25, Issue 5, pp. 725-38, (2007) (PubMed).
Synonyms and alternative names related to DYRK2
dual specificity tyrosine phosphorylation regulated kinase 2 (DYRK2), dual specificity tyrosine-phosphorylation-regulated kinase 2 (CpipJ_CPIJ014802), dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (dyrk2), dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (Dyrk2), dual specificity tyrosine phosphorylation regulated kinase 2 (Dyrk2), dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), 1810038L18Rik, DYRK2, fc18c09, si:ch211-266a5.8, wu:fa09g03, wu:fc18c09Protein level used designations for DYRK2
- dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
- dual specificity tyrosine-phosphorylation-regulated kinase 2
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