Secernin 3 antibody (Center)
Quick Overview for Secernin 3 antibody (Center) (ABIN783657)
Target
See all Secernin 3 (SCRN3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Specificity
- This antibody detects SCRN3. This antibody is predicted to not cross-react with other SCRN members. At least four isoforms of SCRN3 are known to exist, this antibody will recognize all four.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse, Rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- 15 amino acid peptide near the center of human SCRN3
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Secernin 3 (SCRN3)
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Alternative Name
- Secernin-3 (SCRN3)
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Background
- SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
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Gene ID
- 79634
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NCBI Accession
- NP_001180457
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UniProt
- Q0VDG4
Target
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