CNOT7 antibody (N-Term)

Catalog No. ABIN951587

The Rabbit Polyclonal anti-CNOT7 antibody has been validated for WB and EIA. It is suitable to detect CNOT7 in samples from Human.

Quick Overview for CNOT7 antibody (N-Term) (ABIN951587)

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CNOT7 Antibody

Binding Specificity: AA 41-68, N-Term

Specificity: This antibody reacts to CAF-1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human CAF-1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Alternative Name: CNOT7

Background: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.Synonyms: BTG1-binding factor 1, CAF1, CCR4-NOT transcription complex subunit 7, CCR4-associated factor 1

Molecular Weight: 32745 Da

Gene ID: 29883

NCBI Accession: NP_037486

Pathways: Ribonucleoprotein Complex Subunit Organization