GALNS antibody (Middle Region)

Catalog No. ABIN952441

This Rabbit Polyclonal antibody specifically detects GALNS in WB, IF, IHC (p), FACS and EIA. It exhibits reactivity toward Human.

Quick Overview for GALNS antibody (Middle Region) (ABIN952441)

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-GALNS Antibody

Binding Specificity: AA 243-271, Middle Region

Specificity: This antibody recognizes Human GALNS (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human GALNS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GALNS

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Alternative Name: GALNS

Background: This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].Synonyms: Chondroitinase, Chondroitinsulfatase, EC=3.1.6.4, GalNAc6S sulfatase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase

Molecular Weight: 58026 Da

Gene ID: 2588

NCBI Accession: NP_000503

Pathways: Glycosaminoglycan Metabolic Process