GLP2R antibody (Middle Region)

Catalog No. ABIN952529

The Rabbit Polyclonal anti-GLP2R antibody is suitable to detect GLP2R in samples from Human. It has been validated for WB and EIA.

Quick Overview for GLP2R antibody (Middle Region) (ABIN952529)

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLP2R antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-GLP2R Antibody

Binding Specificity: AA 219-248, Middle Region

Specificity: This antibody recognizes Human GLP2R (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 219-248 amino acids from the Central region of human GLP2R

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GLP2R

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Alternative Name: GLP2 Receptor

Background: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq].Synonyms: GLP-2-R, GLP-2R, GLP2R, Glucagon-like peptide 2 receptor

Molecular Weight: 63001 Da

Gene ID: 9340

NCBI Accession: NP_004237

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour