PHOX2B antibody (Middle Region)

Catalog No. ABIN954128

The Rabbit Polyclonal anti-PHOX2B antibody has been validated for WB and EIA. It is suitable to detect PHOX2B in samples from Human and Mouse.

Quick Overview for PHOX2B antibody (Middle Region) (ABIN954128)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PHOX2B Antibody

Binding Specificity: AA 111-138, Middle Region

Specificity: This antibody recognizes PHOX2B (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 111-138) of Human PHOX2B.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background: The DNA-associated protein encoded by the PHOX2B gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.Synonyms: NBPhox, Neuroblastoma Phox, PHOX2B homeodomain protein, PMX2B, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B

Gene ID: 8929

NCBI Accession: NP_003915