PIK3AP1 antibody (C-Term)

Catalog No. ABIN954143

The Rabbit Polyclonal anti-PIK3AP1 antibody has been validated for WB and EIA. It is suitable to detect PIK3AP1 in samples from Human.

Quick Overview for PIK3AP1 antibody (C-Term) (ABIN954143)

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3AP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PIK3AP1 Antibody

Binding Specificity: AA 646-676, C-Term

Specificity: This antibody recognizes PIK3AP1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 646-676aa) of human PIK3AP1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PIK3AP1

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Alternative Name: PIK3AP1

Background: PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. It couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. PIK3AP1 seems to have a complementary role with CD19 in PI3K activation (By similarity) and is may be involved in the survival of mature B cells via activation of REL (By similarity).Synonyms: B-cell adapter for phosphoinositide 3-kinase, BCAP, Phosphoinositide 3-kinase adapter protein 1

Gene ID: 118788

NCBI Accession: NP_689522

Pathways: Activation of Innate immune Response, BCR Signaling, Warburg Effect