POU6F2 antibody (N-Term)

Catalog No. ABIN954262

This Rabbit Polyclonal antibody specifically detects POU6F2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for POU6F2 antibody (N-Term) (ABIN954262)

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU6F2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-POU6F2 Antibody

Binding Specificity: AA 33-61, N-Term

Specificity: This antibody recognizes Human POU6F2 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human POU6F2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POU6F2

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Alternative Name: POU6F2

Background: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Synonyms: POU domain class 6 transcription factor 2, RPF-1, RPF1, Retina-derived POU domain factor 1

Molecular Weight: 72409 Da

Gene ID: 11281

NCBI Accession: NP_001159490