Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 152-181), (Middle Region) antibody

Details for Product No. ABIN954264
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms LOC100136415, 4933429D07Rik, AW742785, Nr1c1, PPAR-alpha, PPARalpha, Ppar, PPAR, NR1C1, nr1c1, hPPAR, xPPARalpha, xppara, PPARALPHA
Epitope
AA 152-181, Middle Region
(14), (13), (8), (8), (6), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(101), (72), (50), (31), (29), (18), (14), (12), (4), (3), (3), (1), (1), (1), (1), (1)
Host
Rabbit
(100), (26)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(98), (33), (25), (23), (20), (16), (14), (6), (4), (4), (2), (2), (2), (2), (2), (2), (1)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954264
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of Human PPAR-alpha Genename: PPARA
Specificity This antibody recognizes Human and Mouse PPAR-alpha (Center).
Purification Affinity Chromatography on Protein A
Alternative Name PPAR-alpha
Background Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Alternate names: NR1C1, Nuclear receptor subfamily 1 group C member 1, PPAR, PPARA, Peroxisome proliferator-activated receptor alpha
Molecular Weight 52225 Da
Gene ID 5465
NCBI Accession NP_001001928
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).

Jablonski, McAteer, de Bakker et al.: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top