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PPARA antibody (C-Term)

PPARA Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778248
  • Target See all PPARA Antibodies
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Binding Specificity
    • 16
    • 16
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 99
    • 90
    • 66
    • 18
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Pig, Horse, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio)
    Host
    • 101
    • 14
    Rabbit
    Clonality
    • 103
    • 12
    Polyclonal
    Conjugate
    • 50
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This PPARA antibody is un-conjugated
    Application
    • 101
    • 46
    • 40
    • 39
    • 39
    • 17
    • 13
    • 13
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LHLQSNHPDD TFLFPKLLQK MVDLRQLVTE HAQLVQVIKK TESDAALHPL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against Ppara. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product PPARA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 468 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Gu, Yang, Lin, Li, Li, Zhong, Peng, Cui: "Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting." in: Hepatology (Baltimore, Md.), Vol. 60, Issue 6, pp. 1929-41, (2014) (PubMed).

  • Target
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Alternative Name
    Ppara (PPARA Products)
    Synonyms
    NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, LOC100136415 antibody, PPARALPHA antibody, nr1c1 antibody, xPPARalpha antibody, xppara antibody, 4933429D07Rik antibody, AW742785 antibody, Nr1c1 antibody, PPAR-alpha antibody, Ppar antibody, peroxisome proliferator activated receptor alpha antibody, peroxisome proliferator-activated receptor alpha antibody, peroxisome proliferator activated receptor alpha L homeolog antibody, PPARA antibody, LOC100136415 antibody, ppara.L antibody, Ppara antibody, ppara antibody
    Background
    As a nuclear steroid receptor, Ppara heterodimerizes with retinoid-X receptor (RXR), and binds to peroxisome proliferator response elements (PPREs) to initiate the transcriptional regulation of target genes.
    Alias Symbols: PPAR
    Protein Interaction Partner: HSP90AA1, Mdm2, Ubc, NRIP1, Dut,
    Protein Size: 468
    Molecular Weight
    51 kDa
    Gene ID
    25747
    NCBI Accession
    NM_013196, NP_037328
    UniProt
    P37230
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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