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PRKAA2 antibody (Middle Region, Thr172)
PRKAA2
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PRKAA2 Antibody
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Target
See all PRKAA2 Antibodies
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Binding Specificity
All epitopes for PRKAA2 antibodies
AA 148-177, Middle Region, Thr172
Reactivity
All reactivities for PRKAA2 antibodies
Human
Host
All hosts for PRKAA2 antibodies
Rabbit
Clonality
All clonalities for PRKAA2 antibodies
Polyclonal
Conjugate
All conjugates for PRKAA2 antibodies
This PRKAA2 antibody is un-conjugated
Application
All applications for PRKAA2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to PRKAA2.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 148-177 amino acids from the Central region of human PRKAA2 (Thr172)
Isotype
Ig Fraction
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Discover our top product PRKAA2 Primary Antibody
Alternatives
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibody
PRKAA2
Reactivity: Human, Mouse, Rat
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PRKAA2
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Target
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Alternative Name
PRKAA2 (PRKAA2 Products )
Synonyms
AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, Ampk antibody, Ampka2 antibody, 2310008I11Rik antibody, A830082D05 antibody, AMPKalpha2 antibody, AMPKA2 antibody, ampk antibody, ampk2 antibody, prkaa antibody, prkaa1 antibody, PRKAA2 antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog antibody, PRKAA2 antibody, Prkaa2 antibody, prkaa2.S antibody, prkaa2 antibody
Background
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK alpha-2 chain, AMPK2
Molecular Weight
62320 Da
Gene ID
5563
NCBI Accession
NP_006243
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Chromatin Binding , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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