SORBS1 antibody (Middle Region)

Catalog No. ABIN954882

Product Details anti-SORBS1 Antibody

Target: SORBS1 (Sorbin and SH3 Domain Containing 1 (SORBS1))

Binding Specificity: AA 869-896, Middle Region

Reactivity: Human, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORBS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human SORBS1 / Ponsin (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 869-896 amino acids from the Central region of Human SORBS1. Genename: SORBS1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SORBS1

Target: SORBS1 (Sorbin and SH3 Domain Containing 1 (SORBS1))

Alternative Name: SORBS1 / Ponsin (SORBS1 Products)

Background: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).Synonyms: CAP, KIAA0894, KIAA1296, SH3D5, SH3P12, Sorbin and SH3 domain-containing protein 1, c-Cbl-associated protein

Molecular Weight: 142497 Da

Gene ID: 10580

NCBI Accession: NP_001030126

Pathways: Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process