ABCB1 antibody
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- Target See all ABCB1 Antibodies
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ABCB1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- LRP-56 reacts with an internal epitope of the LRP-protein (P110), which is strongly over-expressed in various human non-P-glycoprotein MDR tumor cell lines.
- Purification
- Purified
- Immunogen
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Type of Immunogen: Native protein - Clone
- LRP-56
- Isotype
- IgG2b
- Top Product
- Discover our top product ABCB1 Primary Antibody
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- Application Notes
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Approved: Flo, IHC, IHC-Fr, IHC-P
Usage: LRP-56 has potential value for detection of LRP-associated non-Pgp MDR in human tumor samples. Flow cytometry: at least 1:50. Immunocytochemistry: acetone fixed cell preparation at least 1:20-50. Immunohistochemistry: acetone-fixed frozen sections at least 1:20-50, formalin-fixed paraffin embedded tissues 1:20. In Flow cytometry fixate cells in 10 % (v/v) Lysing solution followed by primary antibody and anti-Mouse-FITC. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 1 % BSA, 0.1 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- Alternative Name
- ABCB1 / MDR1 / P Glycoprotein (ABCB1 Products)
- Background
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Name/Gene ID: ABCB1
Subfamily: ATP-binding cassette - ABCB/MDR
Family: Transporter
Synonyms: ABCB1, ABC20, Abcb1b, CLCS, Colchicin sensitivity, CD243, Doxorubicin resistance, IBD13, gp170, MDR1, Multidrug resistance protein 1, P glycoprotein, P-glycoprotein 1, P-GP, CD243 antigen, PGY1 - Gene ID
- 5243
- UniProt
- P08183
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