TLR4 antibody (PE)
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- Target See all TLR4 Antibodies
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Reactivity
- Human, Dog
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TLR4 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
- Purification
- Protein G purified
- Immunogen
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This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).
Type of Immunogen: Cells - Clone
- HTA125
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TLR4 Primary Antibody
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anti-Toll-Like Receptor 4 (TLR4) (AA 751-835) antibody
TLR4 Reactivity: Human, Mouse, Rat, Cow WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibodyTLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 49-247) antibodyTLR4 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Alkaline Phosphatase (AP))TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal Alkaline Phosphatase (AP)
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (HRP)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal HRP
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (FITC)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal FITC
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Biotin)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal Biotin
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (PE)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal PE
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (APC)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal APC
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (PerCP)TLR4 Reactivity: Human WB, FACS, IHC, IF, ICC Host: Rabbit Polyclonal PerCP
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- Application Notes
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Approved: Flo (1 - 2 μg/10 x106)
Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.05 % BSA, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze! Sensitive to light.
- Storage
- 4 °C
- Storage Comment
- Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.
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- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Alternative Name
- TLR4 (TLR4 Products)
- Background
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Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll - Gene ID
- 7099
- UniProt
- O00206
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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