Forkhead Box O1 (FOXO1) antibody

Details for Product No. ABIN966149
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms FOXO1, FOXO1A, fkh1, fkhr, foxo1a, xFoxO1, FKH1, FKHR, AI876417, Afxh, Fkhr1, Foxo1a, Fkhr, FoxO1A, FoxO1a.1, foxo1, zgc:153388
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(316), (176), (152), (65), (65), (65), (49), (2), (1), (1), (1)
Host
Rabbit
(261), (48), (9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Immunohistochemistry (IHC)
(250), (125), (86), (75), (62), (50), (27), (23), (5), (4), (4), (3), (2)
Pubmed 4 references available
Quantity 100 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN966149
398.75 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.
Specificity FKHR (Ab-319) antibody detects endogenous levels of total FKHR protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name FKHR
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Zhao, Gan, Pan et al.: "Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, 2004 (PubMed).

Rena, Woods, Prescott et al.: "Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion." in: The EMBO journal, Vol. 21, Issue 9, pp. 2263-71, 2002 (PubMed).

Rena, Prescott, Guo et al.: "Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting." in: The Biochemical journal, Vol. 354, Issue Pt 3, pp. 605-12, 2001 (PubMed).

Guo, Rena, Cichy et al.: "Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence." in: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 17184-92, 1999 (PubMed).

Validation Images
Did you look for something else?
back to top