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KIT antibody

KIT Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 8D7 unconjugated
Catalog No. ABIN968996
  • Target See all KIT Antibodies
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Reactivity
    • 579
    • 218
    • 63
    • 29
    • 27
    • 25
    • 16
    • 12
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 519
    • 93
    • 26
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 512
    • 131
    • 1
    Monoclonal
    Conjugate
    • 223
    • 63
    • 59
    • 57
    • 46
    • 44
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIT antibody is un-conjugated
    Application
    • 354
    • 325
    • 268
    • 147
    • 91
    • 91
    • 62
    • 44
    • 44
    • 42
    • 30
    • 24
    • 10
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purpose
    C-Kit Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of C-kit expressed in E. Coli.
    Clone
    8D7
    Isotype
    IgG1
    Top Product
    Discover our top product KIT Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mojica, Saxena, Starostik, Cheney: "CD117+ small cell lung cancer lacks the asp 816-->val point mutation in exon 17." in: Histopathology, Vol. 47, Issue 5, pp. 517-22, (2005) (PubMed).

    Tong, Liu, Zhang, Xiong, Liu, Zhang: "Expression of c-kit messenger ribonucleic acid and c-kit protein in sigmoid colon of patients with slow transit constipation." in: International journal of colorectal disease, Vol. 20, Issue 4, pp. 363-7, (2005) (PubMed).

    Nakai, Nonomura, Oka, Shiba, Arai, Nakayama, Inoue, Nishimura, Aozasa, Mizutani, Miki, Okuyama: "KIT (c-kit oncogene product) pathway is constitutively activated in human testicular germ cell tumors." in: Biochemical and biophysical research communications, Vol. 337, Issue 1, pp. 289-96, (2005) (PubMed).

  • Target
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Alternative Name
    C-Kit (KIT Products)
    Background

    Description: C-kit (CD117, 145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

    Aliases: PBT, SCFR, C-Kit, CD117, KIT

    Molecular Weight
    145kDa
    Gene ID
    3815
    HGNC
    3815
    UniProt
    P10721
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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