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Browse our NME1 Proteins (NME1)

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Non-Metastatic Cells 1, Protein (NM23A) Expressed in Proteins (NME1)
On are 36 Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) Proteins from 14 different suppliers available. Additionally we are shipping NME1 Antibodies (285) and NME1 Kits (14) and many more products for this protein. A total of 349 NME1 products are currently listed.
AL024257, AWD, CHH, GAAD, NB, NBR-A, NBR-B, NBS, NDKA, NDK I, NDPK-A, ndpk-b, NDPK-Z1, NDPKA, ndpkb, NDPK I, ndpkz1, NM23, NM23-B, NM23-C1, NM23-H1, nm23-h2, NM23-M1, NM23-Z1, NM23A, nm23b, nm23ndk, nm23ndk-a, nme1, NME1-1, NME1-NME2, nme2, nme2b1, puf, RMRPR, RRP2, T30A10.80, T30A10_80
list all proteins Gene Name GeneID UniProt
NME1 4830 P15531
NME1 18102 P15532
NME1 191575 Q05982

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NME1 Proteins (NME1) by Origin

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Top referenced NME1 Proteins

  1. Human NME1 Protein expressed in Escherichia coli (E. coli) - ABIN2004438 : Fan, Beresford, Oh, Zhang, Lieberman: Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. in Cell 2003 (PubMed)
    Show all 5 references for ABIN2004438

  2. Human NME1 Protein expressed in Wheat germ - ABIN1312683 : Yang, Chevolot, Géhin, Solassol, Mange, Souteyrand, Laurenceau: Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera. in Biosensors & bioelectronics 2012 (PubMed)

More Proteins for NME1 Interaction Partners

Human Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. Nm23-H1 nuclear localized mainly in the G2/M phase and the nuclear Nm23-H1 promoted A549 cell proliferation in vitro.

  2. Differential regulation of NM23-H1 may corroborate/abrogate EMT (show ITK Proteins) depending on the nature of stress, tumor microenvironment and cellular context.

  3. large-scale and well-designed studies, which use uniform antibody and criterion of NM23 positive expression, are required to further validate the role of the NM23 in predicting gastric cancer progression.

  4. Study reveals that NME1L may perform potent biological roles on the cellular behaviors through the extra N-terminal region as well as hexameric conformation. Because the N-terminal region itself has no effect on NF-kappaB (show NFKB1 Proteins) signaling, the dimerization of NME1L is likely a pivotal process to confer the IKKbeta (show IKBKB Proteins) binding ability and subsequent regulation of NF-kappaB (show NFKB1 Proteins) signaling on the region.

  5. A strong association between NME1 heterozygous genotype and breast cancer risk in Kashmiri population

  6. Down-regulation of Dyn1 (show DNM1L Proteins) activity enhances extracellular Nme1 in human colon tumor cell lines.

  7. nm23-H1 and MMP-2 (show MMP2 Proteins) may be as an indicator for esophageal cancer metastasis and prognosis

  8. Results confirmed that NME1L, but not NME1, is likely responsible for regulating breast cancer cell growth by inhibiting IGF1 (show IGF1 Proteins)-stimulated ERK (show EPHB2 Proteins) phosphorylation through N-terminal 25 amino acid-mediated interaction with KSR1 (show KSR1 Proteins).

  9. CRC (show CALR Proteins) patients with NM23-positive tumors had a better prognosis, and thus NM23 expression maybe used as a key prognostic indicator for CRC (show CALR Proteins).

  10. we have identified RMRP as a common target gene of the Wnt (show WNT2 Proteins) and Hippo signaling pathways which could enhance the tumorigenic potential of cancer cells

Mouse (Murine) Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase

  2. data suggested that NME1 acts as a switcher or reprogramming factor which involves in oligodentrocyte versus neuron cell fate specification in vitro

  3. NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma.

  4. NME1 controls annexin IV (show ANXA4 Proteins) and EF-1Balpha amounts by post-translational mechanisms.

  5. data show a critical role for NM23 isoforms in limiting mutagenesis and suppressing UVR-induced melanomagenesis

  6. GAPDH (show GAPDH Proteins) and NDPK are genetic modifiers of murine DDC (show DDC Proteins)-induced liver injury

  7. The work provides a rare instance of nm23-1/NDPKA physiological functions in the mammary glands and reveals its implication as a modulator factor of proliferation and apoptosis in this tissue.

  8. Ha-ras oncogene (show RAB1A Proteins) regulates morphogenesis, tumorigenesis, and metastasis through suppressing nm23 expression and modulation of immune cell function

  9. Data suggested that nm23-M1/NDPK A was involved in the process of blastocyst implantation.

  10. Data show that LMPAB reduced MMP-9 (show MMP9 Proteins) but enhanced nm23-H1 mRNA and protein expression.

Xenopus laevis Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. NDPK-A exists in a functional cellular complex with AMPK (show PRKAA2 Proteins) and CFTR (show CFTR Proteins) in airway epithelia, and NDPK-A catalytic function is required for the AMPK (show PRKAA2 Proteins)-dependent regulation of CFTR (show CFTR Proteins)

Zebrafish Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. NDPKB is required for VEGF (show VEGFA Proteins)-induced angiogenesis and contributes to the correct localization of VEGF receptor (show FLT1 Proteins) type 2 and VE-cadherin (show CDH5 Proteins) at the endothelial adherens junctions.

  2. Data show that NDPK B knockdown embryo results in a severe decrease in cardiac contractility.

Arabidopsis thaliana Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. The physical interaction between phytochrome A in the Pfr form and NDPK-In results in a significant increase in the kinase activity of NDPK-In. The results presented in this work indicate that NDPK-In may function as a protein kinase regulated by light.

NME1 Protein Profile

Protein Summary

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Alternative names and synonyms associated with NME1

  • nucleoside diphosphate kinase (LOC547870)
  • non-metastatic cells 1, protein (NM23A) expressed in (NME1)
  • NME/NM23 nucleoside diphosphate kinase 1 (NME1)
  • NME/NM23 nucleoside diphosphate kinase 1 (Nme1)
  • NME/NM23 nucleoside diphosphate kinase 2 (nme2-b)
  • NME/NM23 nucleoside diphosphate kinase 2 (nme2-a)
  • NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 (nme2b.1)
  • nucleoside diphosphate kinase 1 (NDPK1)
  • RNA component of mitochondrial RNA processing endoribonuclease (RMRP)
  • AL024257 protein
  • AWD protein
  • CHH protein
  • GAAD protein
  • NB protein
  • NBR-A protein
  • NBR-B protein
  • NBS protein
  • NDKA protein
  • NDK I protein
  • NDPK-A protein
  • ndpk-b protein
  • NDPK-Z1 protein
  • NDPKA protein
  • ndpkb protein
  • NDPK I protein
  • ndpkz1 protein
  • NM23 protein
  • NM23-B protein
  • NM23-C1 protein
  • NM23-H1 protein
  • nm23-h2 protein
  • NM23-M1 protein
  • NM23-Z1 protein
  • NM23A protein
  • nm23b protein
  • nm23ndk protein
  • nm23ndk-a protein
  • nme1 protein
  • NME1-1 protein
  • NME1-NME2 protein
  • nme2 protein
  • nme2b1 protein
  • puf protein
  • RMRPR protein
  • RRP2 protein
  • T30A10.80 protein
  • T30A10_80 protein

Protein level used designations for NME1

NDP kinase I , nucleoside diphosphate kinase 1 , nucleoside diphosphate kinase I , non-metastatic cells 1, protein (NM23A) expressed in , NME1-NME2 readthrough transcript , nucleoside diphosphate kinase A , NDK A , NDP kinase A , granzyme A-activated DNase , metastasis inhibition factor nm23 , tumor metastatic process-associated protein , expressed in non-metastatic cells 1 protein , expressed in non-metastatic cells 1, protein , metastasis inhibition factor NM23 , nucleoside-diphosphate kinase 1 , nucleotide diphosphate kinase , NDP kinase beta , expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase) , expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase) , nucloside diphosphate kinase , NDK A2 , NDP kinase A2 , NM23/nucleoside diphosphate kinase A2 , ndk a1 , non-metastatic cells 2, protein (NM23B) expressed in , nucleoside diphosphate kinase A2 , NDK A1 , NDP kinase A1 , NM23/nucleoside diphosphate kinase A1 , ndk a2 , nucleoside diphosphate kinase A1 , non-metastatic cells 2b.1, protein (NM23B) expressed in , nucleoside diphosphate kinase-Z1 , expressed in non-metastatic cells 1 , NDK A 1 , NDK A 2 , NDK NBR-A , NDK NBR-B , NDP kinase A 1 , NDP kinase A 2 , nucleoside diphosphate kinase A 1 , nucleoside diphosphate kinase A 2 , nucleoside diphosphate kinase NBR-A , nucleoside diphosphate kinase NBR-B , nucleoside-diphosphate kinase NBR-A , nucleoside-diphosphate kinase NBR-B

547870 Glycine max
476767 Canis lupus familiaris
100012868 Monodelphis domestica
100172256 Pongo abelii
100406584 Callithrix jacchus
100533953 Pan troglodytes
100533956 Macaca mulatta
100533966 Equus caballus
100533971 Oryctolagus cuniculus
100533973 Ornithorhynchus anatinus
4830 Homo sapiens
18102 Mus musculus
191575 Rattus norvegicus
100142626 Sus scrofa
399333 Xenopus laevis
394350 Xenopus laevis
30083 Danio rerio
422094 Gallus gallus
480558 Canis lupus familiaris
404189 Bos taurus
826515 Arabidopsis thaliana
6023 Homo sapiens
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