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Browse our NME1 Proteins (NME1)

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Non-Metastatic Cells 1, Protein (NM23A) Expressed in Proteins (NME1)
On are 34 Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) Proteins from 14 different suppliers available. Additionally we are shipping NME1 Antibodies (277) and NME1 Kits (11) and many more products for this protein. A total of 336 NME1 products are currently listed.
AL024257, AWD, CHH, GAAD, NB, NBR-A, NBR-B, NBS, NDKA, NDK I, NDPK-A, ndpk-b, NDPK-Z1, NDPKA, ndpkb, NDPK I, ndpkz1, NM23, NM23-B, NM23-C1, NM23-H1, nm23-h2, NM23-M1, NM23-Z1, NM23A, nm23b, nm23ndk, nm23ndk-a, nme1, NME1-1, NME1-NME2, nme2, nme2b1, puf, RMRPR, RRP2, T30A10.80, T30A10_80
list all proteins Gene Name GeneID UniProt
NME1 4830 P15531
NME1 18102 P15532
NME1 191575 Q05982

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NME1 Proteins (NME1) by Origin

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Top referenced NME1 Proteins

  1. Human NME1 Protein expressed in Escherichia coli (E. coli) - ABIN2004438 : Fan, Beresford, Oh, Zhang, Lieberman: Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. in Cell 2003 (PubMed)
    Show all 5 references for ABIN2004438

  2. Human NME1 Protein expressed in Wheat germ - ABIN1312683 : Yang, Chevolot, Géhin, Solassol, Mange, Souteyrand, Laurenceau: Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera. in Biosensors & bioelectronics 2012 (PubMed)

More Proteins for NME1 Interaction Partners

Human Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. CRC (show CALR Proteins) patients with NM23-positive tumors had a better prognosis, and thus NM23 expression maybe used as a key prognostic indicator for CRC (show CALR Proteins).

  2. we have identified RMRP as a common target gene of the Wnt (show WNT2 Proteins) and Hippo signaling pathways which could enhance the tumorigenic potential of cancer cells

  3. NM23 expression is reduced in CRC (show CALR Proteins) tissues and low NM23 levels tightly correlate with higher Dukes stages, poorer differentiation grade, and positive lymph node metastases.

  4. Fibronectin (show FN1 Proteins) is an important effector of the motility-suppressing function of NME1 in melanoma cells.

  5. RMRP mutations can cause short stature and significant immunodeficiency which can be corrected by allogeneic SCT and the diagnosis should be considered even in the absence of skeletal manifestations.

  6. Nm23 loss could be associated with a more favorable environment for the development and dissemination of breast cancer

  7. Dual functions of NME1 in suppression of cell motility and enhancement of genomic stability in melanoma

  8. Regulation of the metastasis suppressor Nm23-H1 by tumor viruses

  9. nm23-H1 protein may be an important prognostic factor in peripheral T-cell lymphoma, not otherwise specified;the nm23-H1-positive group had significantly shorter overall survival (Review).

  10. The case for extracellular Nm23-H1 as a driver of acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) progression

Mouse (Murine) Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase

  2. data suggested that NME1 acts as a switcher or reprogramming factor which involves in oligodentrocyte versus neuron cell fate specification in vitro

  3. NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma.

  4. NME1 controls annexin IV (show ANXA4 Proteins) and EF-1Balpha amounts by post-translational mechanisms.

  5. data show a critical role for NM23 isoforms in limiting mutagenesis and suppressing UVR-induced melanomagenesis

  6. GAPDH (show GAPDH Proteins) and NDPK are genetic modifiers of murine DDC (show DDC Proteins)-induced liver injury

  7. The work provides a rare instance of nm23-1/NDPKA physiological functions in the mammary glands and reveals its implication as a modulator factor of proliferation and apoptosis in this tissue.

  8. Ha-ras oncogene (show RAB1A Proteins) regulates morphogenesis, tumorigenesis, and metastasis through suppressing nm23 expression and modulation of immune cell function

  9. Data suggested that nm23-M1/NDPK A was involved in the process of blastocyst implantation.

  10. Data show that LMPAB reduced MMP-9 (show MMP9 Proteins) but enhanced nm23-H1 mRNA and protein expression.

Xenopus laevis Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. NDPK-A exists in a functional cellular complex with AMPK (show PRKAA2 Proteins) and CFTR (show CFTR Proteins) in airway epithelia, and NDPK-A catalytic function is required for the AMPK (show PRKAA2 Proteins)-dependent regulation of CFTR (show CFTR Proteins)

Zebrafish Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) interaction partners

  1. NDPKB is required for VEGF (show VEGFA Proteins)-induced angiogenesis and contributes to the correct localization of VEGF receptor (show FLT1 Proteins) type 2 and VE-cadherin (show CDH5 Proteins) at the endothelial adherens junctions.

  2. Data show that NDPK B knockdown embryo results in a severe decrease in cardiac contractility.

NME1 Protein Profile

Protein Summary

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Alternative names and synonyms associated with NME1

  • nucleoside diphosphate kinase (LOC547870)
  • non-metastatic cells 1, protein (NM23A) expressed in (NME1)
  • NME/NM23 nucleoside diphosphate kinase 1 (NME1)
  • NME/NM23 nucleoside diphosphate kinase 1 (Nme1)
  • NME/NM23 nucleoside diphosphate kinase 2 (nme2-b)
  • NME/NM23 nucleoside diphosphate kinase 2 (nme2-a)
  • NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 (nme2b.1)
  • nucleoside diphosphate kinase 1 (NDPK1)
  • RNA component of mitochondrial RNA processing endoribonuclease (RMRP)
  • AL024257 protein
  • AWD protein
  • CHH protein
  • GAAD protein
  • NB protein
  • NBR-A protein
  • NBR-B protein
  • NBS protein
  • NDKA protein
  • NDK I protein
  • NDPK-A protein
  • ndpk-b protein
  • NDPK-Z1 protein
  • NDPKA protein
  • ndpkb protein
  • NDPK I protein
  • ndpkz1 protein
  • NM23 protein
  • NM23-B protein
  • NM23-C1 protein
  • NM23-H1 protein
  • nm23-h2 protein
  • NM23-M1 protein
  • NM23-Z1 protein
  • NM23A protein
  • nm23b protein
  • nm23ndk protein
  • nm23ndk-a protein
  • nme1 protein
  • NME1-1 protein
  • NME1-NME2 protein
  • nme2 protein
  • nme2b1 protein
  • puf protein
  • RMRPR protein
  • RRP2 protein
  • T30A10.80 protein
  • T30A10_80 protein

Protein level used designations for NME1

NDP kinase I , nucleoside diphosphate kinase 1 , nucleoside diphosphate kinase I , non-metastatic cells 1, protein (NM23A) expressed in , NME1-NME2 readthrough transcript , nucleoside diphosphate kinase A , NDK A , NDP kinase A , granzyme A-activated DNase , metastasis inhibition factor nm23 , tumor metastatic process-associated protein , expressed in non-metastatic cells 1 protein , expressed in non-metastatic cells 1, protein , metastasis inhibition factor NM23 , nucleoside-diphosphate kinase 1 , nucleotide diphosphate kinase , NDP kinase beta , expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase) , expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase) , nucloside diphosphate kinase , NDK A2 , NDP kinase A2 , NM23/nucleoside diphosphate kinase A2 , ndk a1 , non-metastatic cells 2, protein (NM23B) expressed in , nucleoside diphosphate kinase A2 , NDK A1 , NDP kinase A1 , NM23/nucleoside diphosphate kinase A1 , ndk a2 , nucleoside diphosphate kinase A1 , non-metastatic cells 2b.1, protein (NM23B) expressed in , nucleoside diphosphate kinase-Z1 , expressed in non-metastatic cells 1 , NDK A 1 , NDK A 2 , NDK NBR-A , NDK NBR-B , NDP kinase A 1 , NDP kinase A 2 , nucleoside diphosphate kinase A 1 , nucleoside diphosphate kinase A 2 , nucleoside diphosphate kinase NBR-A , nucleoside diphosphate kinase NBR-B , nucleoside-diphosphate kinase NBR-A , nucleoside-diphosphate kinase NBR-B

547870 Glycine max
476767 Canis lupus familiaris
100012868 Monodelphis domestica
100172256 Pongo abelii
100406584 Callithrix jacchus
100533953 Pan troglodytes
100533956 Macaca mulatta
100533966 Equus caballus
100533971 Oryctolagus cuniculus
100533973 Ornithorhynchus anatinus
4830 Homo sapiens
18102 Mus musculus
191575 Rattus norvegicus
100142626 Sus scrofa
399333 Xenopus laevis
394350 Xenopus laevis
30083 Danio rerio
422094 Gallus gallus
480558 Canis lupus familiaris
404189 Bos taurus
826515 Arabidopsis thaliana
6023 Homo sapiens
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