NME1 Protein (partial) (His tag)

Catalog No. ABIN5608451

Product Details

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Protein Type: Recombinant

Protein Characteristics: partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NME1 protein is labelled with His tag.

Application: Western Blotting (WB)

Sequence: Ala 2 - Glu 152

Purity: >98 % as determined by SDS-PAGE.

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Alternative Name: NME1 (NME1 Products)

Synonyms: AWD Protein, GAAD Protein, NB Protein, NBS Protein, NDKA Protein, NDPK-A Protein, NDPKA Protein, NM23 Protein, NM23-H1 Protein, AL024257 Protein, NM23-M1 Protein, NM23A Protein, NDPK-Z1 Protein, NM23-B Protein, NM23-Z1 Protein, ndpkz1 Protein, nm23b Protein, nme1 Protein, nme2 Protein, nme2b1 Protein, NME1 Protein, NME1-NME2 Protein, NM23-C1 Protein, ndpk-b Protein, ndpkb Protein, nm23-h2 Protein, nm23ndk Protein, puf Protein, NBR-A Protein, NBR-B Protein, NME1-1 Protein, nm23ndk-a Protein, NDK I Protein, NDPK I Protein, T30A10.80 Protein, T30A10_80 Protein, NDP kinase I Protein, NME/NM23 nucleoside diphosphate kinase 1 Protein, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 Protein, non-metastatic cells 1, protein (NM23A) expressed in Protein, NME/NM23 nucleoside diphosphate kinase 2 S homeolog Protein, NME/NM23 nucleoside diphosphate kinase 2 L homeolog Protein, nucleoside diphosphate kinase Protein, nucleoside diphosphate kinase 1 Protein, NME1 Protein, Nme1 Protein, nme2b.1 Protein, nme2.S Protein, nme2.L Protein, LOC547870 Protein, NDPK1 Protein, LOC107790563 Protein

Background: Nucleoside diphosphate kinase A, a member of the NDK family, is also known as NME1, NDP kinase A (NDPA), granzyme A-activated DNase (GAAD), metastasis inhibition factor nm23 (NM23-H1) and tumor metastatic process-associated protein. NME1 plays a major role in the synthesis of nucleoside triphosphates other than ATP. NME1 is also involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Furthermore, NME1 is required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, NME1 works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

Molecular Weight: 18 kDa

Gene ID: 4830

Pathways: Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process