NME1 Protein (AA 2-152) (His tag)
Quick Overview for NME1 Protein (AA 2-152) (His tag) (ABIN2870673)
Target
See all NME1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 2-152
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Purification tag / Conjugate
- This NME1 protein is labelled with His tag.
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Sequence
- AA 2-152
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Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) protein (GST tag)
NME1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) protein (His tag)NME1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % as determined by reducing SDS-PAGE.
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) (Active) proteinNME1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, EAA Active
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) proteinNME1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 2-152), (full length) protein (GST tag)NME1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % SDS, WB, ELISA
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (Transcript Variant 2) protein (His tag)NME1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) proteinNME1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, Co-IP, IP
Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NME1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Alternative Name
- NME1
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Background
- Nucleoside diphosphate kinase A, a member of the NDK family, is also known as NME1, NDP kinase A (NDPA), granzyme A-activated DNase (GAAD), metastasis inhibition factor nm23 (NM23-H1) and tumor metastatic process-associated protein. NME1 plays a major role in the synthesis of nucleoside triphosphates other than ATP. NME1 is also involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Furthermore, NME1 is required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, NME1 works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
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Molecular Weight
- 18.0 kDa
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Pathways
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Target
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