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Browse our anti-NUMA1 (NUMA1) Antibodies

Full name:
anti-Nuclear Mitotic Apparatus Protein 1 Antibodies (NUMA1)
On www.antibodies-online.com are 87 Nuclear Mitotic Apparatus Protein 1 (NUMA1) Antibodies from 21 different suppliers available. Additionally we are shipping NUMA1 Kits (11) and and many more products for this protein. A total of 105 NUMA1 products are currently listed.
Synonyms:
6720401E04Rik, AA764025, AF093576, AI451697, AL022610, AU014979, ha, ihj, nmf4, NUMA, NUMA1, SP-H, sph, Spna-1, Spna1
list all antibodies Gene Name GeneID UniProt
NUMA1 4926 Q14980
NUMA1 101706  
NUMA1 308870  

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Most Popular Reactivities for anti-NUMA1 (NUMA1) Antibodies

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anti-Human NUMA1 Antibodies:

anti-Mouse (Murine) NUMA1 Antibodies:

anti-Rat (Rattus) NUMA1 Antibodies:

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Top referenced anti-NUMA1 Antibodies

  1. Chicken Monoclonal NUMA1 Primary Antibody for IF, IP - ABIN968038 : Elbi, Misteli, Hager: Recruitment of dioxin receptor to active transcription sites. in Molecular biology of the cell 2002 (PubMed)
    Show all 4 references for ABIN968038

  2. Human Monoclonal NUMA1 Primary Antibody for IHC (fro), IHC (p) - ABIN966706 : Compton, Szilak, Cleveland: Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis. in The Journal of cell biology 1992 (PubMed)
    Show all 3 references for ABIN966706

  3. Human Monoclonal NUMA1 Primary Antibody for IF, IP - ABIN1449239 : Schrödel, Volz, de Marco: Fusion tags and chaperone co-expression modulate both the solubility and the inclusion body features of the recombinant CLIPB14 serine protease. in Journal of biotechnology 2005 (PubMed)
    Show all 3 references for ABIN1449239

  4. Human Monoclonal NUMA1 Primary Antibody for EIA, IHC (fro) - ABIN1108502 : Butschak, Harborth, Osborn, Karsten: New monoclonal antibodies recognizing phosphorylated proteins in mitotic cells. in Acta histochemica 1995 (PubMed)
    Show all 2 references for ABIN1108502

  5. Chicken Polyclonal NUMA1 Primary Antibody for WB - ABIN2784222 : Kilpivaara, Rantanen, Tamminen, Aittomäki, Blomqvist, Nevanlinna: Comprehensive analysis of NuMA variation in breast cancer. in BMC cancer 2008 (PubMed)

More Antibodies against NUMA1 Interaction Partners

Cow (Bovine) Nuclear Mitotic Apparatus Protein 1 (NUMA1) interaction partners

  1. The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 (show JUN Antibodies) DNA-binding activity and expression of several transcriptions factors in breast cancer cells.

Human Nuclear Mitotic Apparatus Protein 1 (NUMA1) interaction partners

  1. Suppressor APC domain containing 2 negatively regulates the localization of LGN (show GPSM2 Antibodies) at the cell cortex, likely by competing with NuMA for its binding

  2. NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.During anaphase correct NuMA localization is mediated by direct membrane phospholipid binding.

  3. Retinoblastoma protein (pRB (show RB1 Antibodies)) have a novel function in regulating the mitotic function of NuMA and spindle organization, which are required for proper cell cycle progression.

  4. Study finds that frictional forces increase nonlinearly with microtubule-associated proteins (MAP) velocity across microtubules and depend on filament polarity, with NuMA's friction being lower when moving toward minus ends, EB1 (show MAPRE2 Antibodies)'s lower toward plus ends, and PRC1 (show PRC1 Antibodies)'s exhibiting no directional preference.

  5. The mitosis-dependent dynamic SUMO-1 (show SUMO1 Antibodies) modification of NuMA might contribute to NuMA-mediated formation and maintenance of mitotic spindle poles during mitosis.

  6. ectopic expression of NuMA can manipulate endogenous p53 (show TP53 Antibodies) and p21 (show CDKN1A Antibodies) transcriptional expression during interphase.

  7. ectopic expression of BRAP2 (show BRAP Antibodies) inhibits nuclear localization of HMG20A (show HMG20A Antibodies) and NuMA1, and prevents nuclear envelope accumulation of SYNE2 (show SYNE2 Antibodies).

  8. Hepatocyte Par1b (show MARK2 Antibodies) defines lumen position in concert with the position of the astral microtubule anchoring complex LGN (show GPSM2 Antibodies)-NuMA to yield the distinct epithelial division phenotypes.

  9. NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function.

  10. Phosphorylation of NuMA by aurora-A (show AURKA Antibodies) is important for cell survival.

Mouse (Murine) Nuclear Mitotic Apparatus Protein 1 (NUMA1) interaction partners

  1. Suppressor APC domain containing 2 negatively regulates the localization of LGN (show GPSM2 Antibodies) at the cell cortex, likely by competing with NuMA for its binding

  2. a new function for spectrins in the stability of invadosomes and the coupling between actin regulation and ECM (show MMRN1 Antibodies) degradation

  3. Calcium plays a role in regulating the expression and function of beta-adducin to sustain normal organization of the spectrin-based cytoskeleton and the differentiation properties in keratinocytes through the calmodulin/EGFR/cadherin signaling pathway.

  4. Loss of 4.1/NuMA interaction results in spindle orientation defects and inhibition of Cdk1 (show CDK1 Antibodies) causes increase in cortical NuMA localization

  5. ectopic expression of BRAP2 (show BRAP Antibodies) inhibits nuclear localization of HMG20A (show HMG20A Antibodies) and NuMA1, and prevents nuclear envelope accumulation of SYNE2 (show SYNE2 Antibodies).

  6. organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta (show PKCd Antibodies)(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin

  7. Results of this study provide evidence for a role for spectrin in different steps of megakaryocyte development through its participation in the formation of invaginated membranes and in the maintenance of proplatelet structure.

  8. Analysis of 3 new alleles reveals previously unknown consequences of red blood cell (RBC (show CACNA1C Antibodies)) spectrin deficiency, resulting in markedly reduced RBC (show CACNA1C Antibodies) membrane spectrin content, decreased band 3 (show SLC4A1 Antibodies), and absent beta-adducin (show ADD2 Antibodies).

  9. Murine recessive hereditary spherocytosis, sph/sph, is caused by a mutation in the erythroid alpha-spectrin (show SPTA1 Antibodies) gene.

  10. Fusion protein NuMA-RARalpha (show RARA Antibodies) cooperates with RXRalpha (show RXRA Antibodies) in the development of leukemia in hCG (show CGA Antibodies)-NuMA-RARalpha (show RARA Antibodies) transgenic mice.

NUMA1 Antigen Profile

Antigen Summary

Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.

Alternative names and synonyms associated with NUMA1

  • nuclear mitotic apparatus protein 1 (NUMA1) antibody
  • nuclear mitotic apparatus protein 1 (numa1) antibody
  • nuclear mitotic apparatus protein 1 (Numa1) antibody
  • nuclear mitotic apparatus protein 1-like (LOC100526064) antibody
  • spectrin alpha, erythrocytic 1 (Spta1) antibody
  • 6720401E04Rik antibody
  • AA764025 antibody
  • AF093576 antibody
  • AI451697 antibody
  • AL022610 antibody
  • AU014979 antibody
  • ha antibody
  • ihj antibody
  • nmf4 antibody
  • NUMA antibody
  • NUMA1 antibody
  • SP-H antibody
  • sph antibody
  • Spna-1 antibody
  • Spna1 antibody

Protein level used designations for NUMA1

nuclear mitotic apparatus protein 1 , nuclear mitotic apparatus protein 1-like , SP-H antigen , centrophilin stabilizes mitotic spindle in mitotic cells , structural nuclear protein , alpha-spectrin 1, erythroid , erythroid alpha-spectrin , hemolytic anemia , neuroscience mutagenesis facility, 4 , spectrin alpha 1 , spectrin alpha chain, erythrocyte , spectrin alpha chain, erythrocytic 1 , spherocytosis

GENE ID SPECIES
451398 Pan troglodytes
485213 Canis lupus familiaris
513091 Bos taurus
718231 Macaca mulatta
100015927 Monodelphis domestica
100052884 Equus caballus
100127473 Sus scrofa
100439501 Pongo abelii
100489026 Xenopus (Silurana) tropicalis
4926 Homo sapiens
101706 Mus musculus
308870 Rattus norvegicus
768717 Gallus gallus
100302677 Oryctolagus cuniculus
100526064 Sus scrofa
20739 Mus musculus
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