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Browse our anti-Aurora A (AURKA) Antibodies

Full name:
anti-Aurora Kinase A Antibodies (AURKA)
On www.antibodies-online.com are 243 Aurora Kinase A (AURKA) Antibodies from 28 different suppliers available. Additionally we are shipping Aurora A Proteins (25) and Aurora A Kits (1) and many more products for this protein. A total of 289 Aurora A products are currently listed.
Synonyms:
87A7-9/2, AIK, AIRK1, ARK-1, Ark1, AU019385, aur-a, AURA, aurka, aurka-a, Aurora-A, AURORA2, AW539821, Ayk1, BTAK, CG3068, ck10, ck[10], Dmel\\CG3068, Eg2, IAK, IAK1, l(3)87Ac, l(3)ck10, pEg2, PPP1R47, Stk6, STK7, STK15, wu:fb37c10, wu:fc02c02, zgc:100912
list all antibodies Gene Name GeneID UniProt
AURKA 6790 O14965
AURKA 20878 P97477
AURKA 261730  

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Most Popular Reactivities for anti-Aurora A (AURKA) Antibodies

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anti-Human Aurora A Antibodies:

anti-Mouse (Murine) Aurora A Antibodies:

anti-Rat (Rattus) Aurora A Antibodies:

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Top referenced anti-Aurora A Antibodies

  1. Human Monoclonal Aurora A Primary Antibody for IF, WB - ABIN393835 : Molli, Li, Bagheri-Yarmand, Pakala, Katayama, Sen, Iyer, Chernoff, Tsai, Nair, Kumar: Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. in The Journal of cell biology 2010 (PubMed)
    Show all 5 references for ABIN393835

  2. Human Monoclonal Aurora A Primary Antibody for IF, WB - ABIN968260 : Gopalan, Chan, Donovan: A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators. in The Journal of cell biology 1997 (PubMed)
    Show all 4 references for ABIN968260

  3. Human Monoclonal Aurora A Primary Antibody for ICC, FACS - ABIN968971 : Veerakumarasivam, Goldstein, Saeb-Parsy, Scott, Warren, Thorne, Mills, Venkitaraman, Neal, Kelly: AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma. in Cell cycle (Georgetown, Tex.) 2008 (PubMed)
    Show all 2 references for ABIN968971

  4. Human Polyclonal Aurora A Primary Antibody for IHC (p), WB - ABIN392389 : Kimura, Kotani, Hattori, Sumi, Yoshioka, Todokoro, Okano: Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. in The Journal of biological chemistry 1997 (PubMed)

  5. Human Polyclonal Aurora A Primary Antibody for ELISA, WB - ABIN184572 : Zhou, Kuang, Zhong, Kuo, Gray, Sahin, Brinkley, Sen: Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. in Nature genetics 1998 (PubMed)

  6. Human Monoclonal Aurora A Primary Antibody for IF, WB - ABIN181948 : Cremet, Descamps, Vérite, Martin, Prigent: Preparation and characterization of a human aurora-A kinase monoclonal antibody. in Molecular and cellular biochemistry 2003 (PubMed)

  7. Cow (Bovine) Polyclonal Aurora A Primary Antibody for IHC, WB - ABIN2777171 : Ye, Yang, Grossman, Dinney, Wu, Gu: Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. in Cancer 2008 (PubMed)

  8. Human Polyclonal Aurora A Primary Antibody for IF (p), IHC (p) - ABIN683398 : Ye, Li, Yang, Wang, Hao, Wang, Li, Du, Hao, Liu, Wang, Xia, Huang, Sun, Tian, Fan: Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation. in The Journal of experimental medicine 2014 (PubMed)

More Antibodies against Aurora A Interaction Partners

Fruit Fly (Drosophila melanogaster) Aurora Kinase A (AURKA) interaction partners

  1. Disrupting the spindle assembly checkpoint in the aurA mutant does not prevent neuroblast amplification, tumor formation or chromosome segregation.

  2. Aurora A kinase activity contributes to phosphorylation of kinetochore substrates near poles and its inhibition results in chromosome misalignment and an increased incidence of erroneous kinetochore-MT attachments.

  3. AurA and aPKC exert the spatiotemporal control of Lgl distribution to achieve unique cell polarity roles in distinct cell types.

  4. Aurora A and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.

  5. Drosophila melanogaster aurora A phosphorylates the dynactin (show DCTN1 Antibodies) subunit p150(glued (show DCTN1 Antibodies)) on sites required for its association with the mitotic spindle.

  6. One of the functions of Aurora A kinase is to direct centrosomal organization such that D-TACC complexed to the MSPS/XMAP215 (show CKAP5 Antibodies) microtubule-associated protein (show FAM82A2 Antibodies) may be recruited, and thus modulate the behavior of astral microtubules.

  7. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.

  8. Deletion mapping identifies a central domain of Aurora-A as essential for its centrosomal localization that is augmented by both the amino and the carboxyl terminal ends of the protein.

  9. Results suggest that Aurora-A regulates centrosome assembly by controlling centrosomin's (CNN) ability to target and/or anchor gamma-tubulin (show TUBG1 Antibodies) to the centrosome and to organize microtubule-nucleating sites via interaction with CNN.

  10. Aurora-A is essential for many crucial events during mitosis and phosphorylation of a series of substrates by Aurora-A at different stages of mitosis may promote diverse critical events in mitosis to maintain chromosome integrity in cells

Zebrafish Aurora Kinase A (AURKA) interaction partners

  1. Zebrafish Aurora-A is critically required for embryonic proliferation during development.

Human Aurora Kinase A (AURKA) interaction partners

  1. Aurora kinases are important KRAS targets in lung cancer.

  2. Aurora A and B inhibition had a significant antitumor effect against TNBC, and this antitumor effect was maximized by the combination of selumetinib with Aurora A and B inhibition.

  3. Aurora kinase A has a role in inducing papillary thyroid cancer lymph node metastasis by promoting cofilin-1 (show CFL1 Antibodies) activity

  4. we show for the first time that targeting of the Aurora A kinase in mice using drugs such as Alisertib results in a curative sterilizing therapy that may be useful in treating HPV-driven cancers.

  5. Augmented expression of Aurora kinase-A and Polo-like kinase-1 (show PLK1 Antibodies) at the lactogenic switch likely mediates the formation of binucleated cells.

  6. Aurora A kinase inhibitor alisertib 60 mg/m(2) per dose for 7 days is tolerable with a standard irinotecan and temozolomide backbone and has promising response and progression-free survival rates in neuroblastoma (show ARHGEF16 Antibodies).

  7. Aurora A inhibition causes delocalized clustering of Lck (show LCK Antibodies) at the immunological synapses and decreases its phosphorylation levels thus indicating Aurora A is required for maintaining Lck (show LCK Antibodies) active during T-cell activation.

  8. Combined treatment with aurora kinase inhibitor SNS (show SCN10A Antibodies)-314and quercetin-hyaluronic acid hydrogel results in synergistic cytotoxic effects in papillary and medullary thyroid carcinoma cells.

  9. PC4 (show IFRD1 Antibodies) associates with Aurora A and Aurora B (show AURKB Antibodies) and undergoes phosphorylation, following which PC4 (show IFRD1 Antibodies) activates both Aurora A and B to sustain optimal kinase activity to maintain the phosphorylation gradient for the proper functioning of the mitotic machinery.

  10. Ndel1 (show NDEL1 Antibodies) acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.

Mouse (Murine) Aurora Kinase A (AURKA) interaction partners

  1. Augmented expression of Aurora kinase-A and Polo-like kinase-1 (show PLK1 Antibodies) at the lactogenic switch likely mediates the formation of binucleated cells.

  2. Aurora A inhibition causes delocalized clustering of Lck (show LCK Antibodies) at the immunological synapses and decreases its phosphorylation levels thus indicating Aurora A is required for maintaining Lck (show LCK Antibodies) active during T-cell activation.

  3. Ndel1 (show NDEL1 Antibodies) acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.

  4. The Aurora kinase A and c-Myc (show MYC Antibodies) expression and histone H3 (show HIST3H3 Antibodies) phosphorylation level were comparatively higher in the cranial tumor than the caudal (show CAD Antibodies).

  5. aurora kinase A (AURKA) represents a new therapeutic target in primary myelofibrosis.

  6. A novel function was identified for Aurora-A in controlling the polarization of macrophages and inflammation.

  7. Wdr62 (show WDR62 Antibodies) interacts with Aurora A to control mitotic progression, and loss of these interactions leads to mitotic delay and cell death of NPCs, which could be a potential cause of human microcephaly.

  8. Reduced levels of Aurora A protein immediately post-thaw may be associated with the impaired oocyte maturation manifested by the delayed progression through meiosis

  9. Aurka is required for hematopoiesis, but is dispensable for megakaryocyte endomitosis.

  10. Aurora-A kinase does not regulate TACC3 (show TACC3 Antibodies)-chTOG (show CKAP5 Antibodies) complex formation, indicating that Aurora-A solely functions as a recruitment factor for the TACC3 (show TACC3 Antibodies)-chTOG (show CKAP5 Antibodies) complex to centrosomes and proximal mitotic spindles.

Cow (Bovine) Aurora Kinase A (AURKA) interaction partners

  1. Aurora A was the most abundant form in oocytes, both at mRNA and protein levels, in bovine oocytes during meiotic maturation.

Pig (Porcine) Aurora Kinase A (AURKA) interaction partners

  1. Aurora kinase A is unlikely to be involved in CPEB1 (show CPEB1 Antibodies) activating phosphorylation and cyclin B1 (show CCNB1 Antibodies) mRNA polyadenylation during meiotic maturation of porcine oocytes.

  2. Aurora-A may be a multifunctional kinase that plays pivotal regulatory roles in microtubule assembly during porcine oocyte meiotic maturation, fertilization and early embryonic mitosis

  3. Aurora A stimulates the protein synthesis and promotes the meiotic resumption.

Xenopus laevis Aurora Kinase A (AURKA) interaction partners

  1. These results suggest a novel relationship between AurA and protein phosphatases during progression throughout the early embryonic cell cycle and shed new light on potential defects caused by AurA overexpression.

  2. MCAK (show KIF2C Antibodies) colocalized with NuMA (show NUMA1 Antibodies) and XMAP215 (show CKAP5 Antibodies) at the center of Ran asters where its activity is regulated by Aurora A-dependent phosphorylation of S196, which contributes to proper pole focusing

  3. Plx1 (show PLK1 Antibodies) promotes activation of Aurora A, most likely through TPX2.

  4. Aurora-A kinase is required for astral microtubule polymerization and spindle microtubule flux during chromosome segregation.

  5. Data show that Aurora A is a key regulator of microtubule assembly during M phase and therefore of bipolar spindle formation.

  6. binding and elution properties of both the phosphopeptides and unphosphorylated peptides of His6-Aurora A

  7. Results suggest that phosphorylation of maskin (show TACC3 Antibodies) by Aurora-A prevents meiosis II proteins from being produced during meiosis I.

  8. The N-terminal non-catalytic domain of Aurora-A can localize to the centrosome in Xenopus egg extracts, while GFP fusions of either the N-terminal or catalytic domains are targeted to the centrosome in Xenopus XL2 cells.

  9. Here we identify G205 in Xenopus Aurora A as a key determinant of both intrinsic activity and regulation by TPX2

  10. The catalytic domain alone of Aurora-A is sufficient to restore spindle bipolarity; additional N-terminal sequences function in mitotic timing.

Aurora A (AURKA) Antigen Profile

Antigen Summary

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Aurora A (AURKA)

  • aurora (aur) antibody
  • aurora kinase A (aurka) antibody
  • hypothetical protein (Aurora-A) antibody
  • aurora kinase A (AURKA) antibody
  • aurora kinase A (Aurka) antibody
  • 87A7-9/2 antibody
  • AIK antibody
  • AIRK1 antibody
  • ARK-1 antibody
  • Ark1 antibody
  • AU019385 antibody
  • aur-a antibody
  • AURA antibody
  • aurka antibody
  • aurka-a antibody
  • Aurora-A antibody
  • AURORA2 antibody
  • AW539821 antibody
  • Ayk1 antibody
  • BTAK antibody
  • CG3068 antibody
  • ck10 antibody
  • ck[10] antibody
  • Dmel\\CG3068 antibody
  • Eg2 antibody
  • IAK antibody
  • IAK1 antibody
  • l(3)87Ac antibody
  • l(3)ck10 antibody
  • pEg2 antibody
  • PPP1R47 antibody
  • Stk6 antibody
  • STK7 antibody
  • STK15 antibody
  • wu:fb37c10 antibody
  • wu:fc02c02 antibody
  • zgc:100912 antibody

Protein level used designations for anti-Aurora Kinase A (AURKA) Antibodies

A-type aurora kinase , AuroraA , CG3068-PA , aur-PA , aurora A , aurora A kinase , aurora kinase , aurora-A , early-A , fruhe2 , Aurora A , hypothetical protein , aurora kinase A , fb37c10 , fc02c02 , serine/threonine-protein kinase 6 , serine/threonine protein kinase 6 , aurora A kinase protein , serine/threonine-protein kinase 6-like , ARK-1 , Aurora-A kinase , IPL1-related kinase , aurora 2 , aurora-related kinase 1 , aurora/IPL1-like kinase , aurora/IPL1-related kinase 1 , breast tumor-amplified kinase , breast-tumor-amplified kinase , hARK1 , protein phosphatase 1, regulatory subunit 47 , serine/threonine kinase 6 , serine/threonine protein kinase 15 , serine/threonine-protein kinase 15 , serine/threonine-protein kinase aurora-A , aurora family kinase 1 , ipl1- and aurora-related kinase 1 , serine/threonine-protein kinase Ayk1 , ratAurA , Aurora-A , Serine/threonine-protein kinase 6 , aurora kinase A-A , p46Eg265 , pEg2 , serine/threonine-protein kinase 6-A , serine/threonine-protein kinase Eg2 , serine/threonine-protein kinase Eg2-A

GENE ID SPECIES
41446 Drosophila melanogaster
549324 Xenopus (Silurana) tropicalis
7200473 Phaeodactylum tricornutum CCAP 1055/1
428167 Gallus gallus
445246 Danio rerio
469980 Pan troglodytes
698190 Macaca mulatta
100216431 Ovis aries
100303586 Saccoglossus kowalevskii
100398107 Callithrix jacchus
100459866 Pongo abelii
100469600 Ailuropoda melanoleuca
6790 Homo sapiens
20878 Mus musculus
261730 Rattus norvegicus
504437 Bos taurus
485940 Canis lupus familiaris
574063 Sus scrofa
397925 Xenopus laevis
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