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Aurora A antibody (C-Term)

AURKA Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855868
  • Target See all Aurora A (AURKA) Antibodies
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Binding Specificity
    • 28
    • 22
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 124
    • 72
    • 40
    • 20
    • 18
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 122
    • 19
    • 1
    Rabbit
    Clonality
    • 109
    • 32
    Polyclonal
    Conjugate
    • 80
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aurora A antibody is un-conjugated
    Application
    • 103
    • 59
    • 37
    • 23
    • 18
    • 15
    • 11
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to Aurora A (aurora kinase A)
    Aurora A antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Aurora A. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product AURKA Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.87 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Alternative Name
    aurora kinase A (AURKA Products)
    Synonyms
    AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody
    Background
    The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Centrosome , Spindle
    Molecular Weight
    46 kDa
    Gene ID
    6790
    UniProt
    O14965
    Pathways
    Cell Division Cycle, Asymmetric Protein Localization
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