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ATR Antibodies

(ATR serine/threonine kinase (ATR))
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008].
ATR antibody  (AA 366-550) ATR antibody  (AA 366-550) ATR antibody (AA 366-550) (ABIN7193431)

ATR Reactivity: Human ELISA, FACS, WB Host: Mouse Monoclonal 3G6D2 unconjugated

ATR antibody  (pThr1989) ATR antibody  (pThr1989) ATR antibody (pThr1989) (ABIN7265777)

ATR Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated

ATR antibody  (Internal Region) ATR antibody  (Internal Region) ATR antibody (Internal Region) (ABIN6656919)

ATR Reactivity: Human ELISA, FM, IHC, WB Host: Rabbit Polyclonal unconjugated

ATR Antibodies by Reactivity

Find ATR Antibodies for a variety of species such as anti-Human ATR, anti-Mouse ATR, anti-Rat ATR. The species listed below are among those available. Click on a link to go to the corresponding products.

ATR Antibodies by Application

Find ATR Antibodies validated for a specific application such as ELISA, WB, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ATR Antibodies by Host

Find ATR Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

ATR Antibodies by Binding Specificity

Find ATR Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ATR Antibodies by Clonality

Find available monoclonal or polyclonal ATR Antibodies. Click on a link to go to the corresponding products.

ATR Antibodies by Clone

Find ATR Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

ATR Antibodies by Conjugate

Find ATR Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ATR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (4)
Cat. No. ABIN7265777
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6656919
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, WB
Validations
  • (3)
Cat. No. ABIN6656920
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7169011
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN6255330
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, WB
Validations
  • (2)
Cat. No. ABIN7307510
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1030269
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IHC (p), ELISA
Validations
  • (2)
Cat. No. ABIN1723439
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN3183446
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7138618
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7254349
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN233834
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6137358
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6137357
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN1532115
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ATR Antibodies

Kim, Zhao, Wu, Qin, Nowsheen, Huang, Zhou, Chen, Deng, Guo, Luo, Lou, Yuan: "ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex." in: Nature communications, Vol. 10, Issue 1, pp. 5304, (2019) (PubMed).

Morales, Carrero, Hung, Tubbs, Andrews, Edelson, Calderon, Innes, Paules, Payton, Sleckman: "A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages." in: eLife, Vol. 6, (2017) (PubMed).

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, (2013) (PubMed).

Oku, Nakano, Kaneko, Ando, Kenmotsu, Itoh, Tsuiji, Seyama, Toyoshima, Tsuji: "Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin." in: The Journal of biological chemistry, Vol. 287, Issue 51, pp. 42910-20, (2012) (PubMed).

Haro, Sheth, Scheinberg: "Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e48841, (2012) (PubMed).

Chen, Chen, Riley, Chen: "Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR." in: Cell cycle (Georgetown, Tex.), Vol. 10, Issue 4, pp. 655-63, (2011) (PubMed).

Ha, Fiskus, Rao, Balusu, Venkannagari, Nalabothula, Bhalla: "Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage." in: Molecular cancer therapeutics, Vol. 10, Issue 7, pp. 1194-206, (2011) (PubMed).

McNees, Tejera, Martínez, Murga, Mulero, Fernandez-Capetillo, Blasco: "ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase." in: The Journal of cell biology, Vol. 188, Issue 5, pp. 639-52, (2010) (PubMed).

Zuco, Benedetti, Zunino: "ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968." in: Cancer letters, Vol. 292, Issue 2, pp. 186-96, (2010) (PubMed).

Boichuk, Hu, Hein, Gjoerup: "Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen." in: Journal of virology, Vol. 84, Issue 16, pp. 8007-20, (2010) (PubMed).

Aliases for ATR Antibodies

ATR serine/threonine kinase (ATR) Antibodies
ataxia telangiectasia and Rad3 related (ATR) Antibodies
ataxia telangiectasia and Rad3 related (Atr) Antibodies
ATR serine/threonine kinase (Atr) Antibodies
FCTCS Antibodies
FRP1 Antibodies
MEC1 Antibodies
SCKL Antibodies
SCKL1 Antibodies
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