Aurora A antibody (AA 1-110)

Catalog No. ABIN563053

This Mouse Monoclonal antibody specifically detects Aurora A in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for Aurora A antibody (AA 1-110) (ABIN563053)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5F8

Product Details anti-Aurora A Antibody

Binding Specificity: AA 1-110

Purpose: Mouse monoclonal antibody raised against a partial recombinant STK6.

Sequence: MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AURKA (NP_940835, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Aurora A antibody (ABIN563053)

Lo Iacono, Monica, Saviozzi, Ceppi, Bracco, Papotti, Scagliotti: "Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation." in: Journal of translational medicine, Vol. 9, pp. 100, (2011) (PubMed).

Xiao, Chen, Ji, Volle, Lewis, Tsai, Dong: "KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1." in: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36304-15, (2011) (PubMed).

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: AURKA

Background: Full Gene Name: aurora kinase A
Synonyms: AIK,ARK1,AURA,AURORA2,BTAK,MGC34538,STK15,STK6,STK7

Gene ID: 6790

NCBI Accession: NM_198433

Pathways: Cell Division Cycle, Asymmetric Protein Localization