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Browse our anti-CDK6 (CDK6) Antibodies

Full name:
anti-Cyclin-Dependent Kinase 6 Antibodies (CDK6)
On are 232 Cyclin-Dependent Kinase 6 (CDK6) Antibodies from 24 different suppliers available. Additionally we are shipping CDK6 Kits (10) and CDK6 Proteins (10) and many more products for this protein. A total of 266 CDK6 products are currently listed.
5830411I20, AI504062, CDK6, Crk2, PLSTIRE
list all antibodies Gene Name GeneID UniProt
CDK6 1021 Q00534
CDK6 12571 Q64261
CDK6 114483  

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Most Popular Reactivities for anti-CDK6 (CDK6) Antibodies

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anti-Human CDK6 Antibodies:

anti-Mouse (Murine) CDK6 Antibodies:

anti-Rat (Rattus) CDK6 Antibodies:

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Top referenced anti-CDK6 Antibodies

  1. Human Monoclonal CDK6 Primary Antibody for IF, WB - ABIN393888 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393888

  2. Human Polyclonal CDK6 Primary Antibody for IHC (p) - ABIN319413 : Flores-Rozas, Kelman, Dean, Pan, Harper, Elledge, ODonnell, Hurwitz: Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 3 references for ABIN319413

  3. Human Polyclonal CDK6 Primary Antibody for IF, IHC (p) - ABIN401596 : Hirai, Roussel, Kato, Ashmun, Sherr: Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. in Molecular and cellular biology 1995 (PubMed)
    Show all 3 references for ABIN401596

  4. Human Polyclonal CDK6 Primary Antibody for IF, IHC (p) - ABIN319289 : Pestell, Albanese, Reutens, Segall, Lee, Arnold: The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. in Endocrine reviews 1999 (PubMed)
    Show all 3 references for ABIN319289

  5. Human Polyclonal CDK6 Primary Antibody for IF, IHC (p) - ABIN319411 : Lukas, Bartkova, Bartek: Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint. in Molecular and cellular biology 1997 (PubMed)
    Show all 3 references for ABIN319411

  6. Human Monoclonal CDK6 Primary Antibody for IF, WB - ABIN1106651 : Lien, Lin, Huang, Chang, Hsu: Expression of cyclin-dependent kinase 6 (cdk6) and frequent loss of CD44 in nasal-nasopharyngeal NK/T-cell lymphomas: comparison with CD56-negative peripheral T-cell lymphomas. in Laboratory investigation; a journal of technical methods and pathology 2000 (PubMed)
    Show all 3 references for ABIN1106651

  7. Human Monoclonal CDK6 Primary Antibody for IP, WB - ABIN488121 : Tsubari, Taipale, Tiihonen, Keski-Oja, Laiho: Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity. in Molecular and cellular biology 1999 (PubMed)
    Show all 2 references for ABIN488121

  8. Human Monoclonal CDK6 Primary Antibody for IHC (fro), IP - ABIN119189 : Elledge: Cell cycle checkpoints: preventing an identity crisis. in Science (New York, N.Y.) 1997 (PubMed)

  9. Cow (Bovine) Polyclonal CDK6 Primary Antibody for WB - ABIN2792149 : Mendrzyk, Radlwimmer, Joos, Kokocinski, Benner, Stange, Neben, Fiegler, Carter, Reifenberger, Korshunov, Lichter: Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 (PubMed)

  10. Human Polyclonal CDK6 Primary Antibody for IF (p), IHC (p) - ABIN670236 : Yang, Wang, Hui, Li, Jiang: SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/β-catenin pathway. in Tumour biology 2015 (PubMed)

More Antibodies against CDK6 Interaction Partners

Human Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. concurrent inhibition of ESR1 (show ESR1 Antibodies) and the cyclin (show PCNA Antibodies)-dependent kinases 4 and 6 (CDK4/6 (show CDK4 Antibodies)) significantly increased progression-free survival in advanced patients

  2. three uniquely identified proteins (CDK6 , galectin-3-binding protein (show LGALS3BP Antibodies) and LDH C (show LDHC Antibodies)) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer

  3. Downregulation of microRNA33a promotes the expression CDK6, CCND1 (show CCND1 Antibodies), and PIM1 (show PIM1 Antibodies), and gastric cancer cell proliferation.

  4. MiR (show MLXIP Antibodies)-26a and mir (show MLXIP Antibodies)-584 inhibit the binding of hnRNP A1 (show HNRNPA1 Antibodies)-CDK6 mRNA and induce colorectal cancer cell apoptosis.

  5. only miR (show MLXIP Antibodies)-34a was prognostic for RFS (RR, 11.5; P = 0.027). miR (show MLXIP Antibodies)-34a expression was inversely correlated with that of c-MET and CDK6 in non-small cell lung cancer , and had prognostic significance for RFS, especially in adenocarcinoma patients.

  6. The results of clinical trials with oral CDK4/6 (show CDK4 Antibodies) inhibitors to date have offered promising glimpses of significant activity in hormone-sensitive breast cancer.

  7. The CDK6-cyclin D3 (show CCND3 Antibodies) pair play a fundamental role in controlling CDK2 (show CDK2 Antibodies)-dependent SAMHD1 (show SAMHD1 Antibodies) phosphorylation and the dNTP pool in primary macrophages.

  8. We conclude that Bz-surviving MM cells display a GRP78 (show HSPA5 Antibodies)(HIGH)/p21 (show CDKN1A Antibodies)(HIGH)/CDK6(LOW)/P-Rb(LOW) profile, and these markers may identify quiescent MM cells capable of fueling recurrences.

  9. differential expression of CDK6 underlies heterogeneity in stem cell quiescence states that functionally regulates this highly regenerative system

  10. MiR (show MLXIP Antibodies)-211 is a tumor suppressor that controls expression of Cyclin D1 (show CCND1 Antibodies) and CDK6.

Mouse (Murine) Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. Notch3 (show NOTCH3 Antibodies) transcription and growth of lymphoma cells was dependent on CDK6.

  2. CDK6 is an important regulator of stem cell activation and an essential component of a transcriptional complex that suppresses Egr1 (show EGR1 Antibodies) in hematopoietic and leukemic stem cell activation

  3. Cdk4 (show CDK4 Antibodies) and Cdk6 cooperate in hematopoietic tumor development and suggest a role for Cdk6 in sequestering INK4 (show CDKN2A Antibodies) proteins away from Cdk4 (show CDK4 Antibodies).

  4. Cdk6/Ccnd1 (show CCND1 Antibodies) overexpression inhibits chondrocyte maturation and enhances G1/S transition by phosphorylating pRb (show PGR Antibodies); the chondrocytes then undergo p53 (show TP53 Antibodies)-dependent apoptosis

  5. p107 (show RBL1 Antibodies) retinoblastoma protein is regulated by Cdk6/Ccnd1 (show CCND1 Antibodies) in growth plates.

  6. A chrysin derivative suppresses skin cancer growth by inhibiting cyclin (show PCNA Antibodies)-dependent kinases.

  7. Cdk6 deficiency prevents the expansion of neuronally committed precursors by lengthening G(1) phase duration, reducing concomitantly the production of newborn neurons

  8. a mechanism for LPS (show TLR4 Antibodies) signaling which involves a decrease in miR (show MLXIP Antibodies)-107 leading to an increase in CDK6

  9. an important role for CDK6 kinase activity in thymocyte development that operates partially through modulating Notch (show NOTCH1 Antibodies) target gene expression.

  10. we identify CDK6 as relevant and critical target of AP-1 (show JUN Antibodies)-regulated DNA methylation (show HELLS Antibodies) on BCR-ABL (show ABL1 Antibodies)-induced transformation, thereby accelerating leukemogenesis

Cow (Bovine) Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. the T-1075C SNP of bovine CDK6 is significantly associated with body length and heart girth

CDK6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with CDK6

  • cyclin-dependent kinase 6 (CDK6) antibody
  • cyclin-dependent kinase 6 (Cdk6) antibody
  • 5830411I20 antibody
  • AI504062 antibody
  • CDK6 antibody
  • Crk2 antibody
  • PLSTIRE antibody

Protein level used designations for CDK6

cyclin-dependent kinase 6 , cell division protein kinase 6-like , cell division protein kinase 6 , serine/threonine-protein kinase PLSTIRE , CR2 protein kinase

746968 Pan troglodytes
100454924 Pongo abelii
1021 Homo sapiens
12571 Mus musculus
114483 Rattus norvegicus
609920 Canis lupus familiaris
511754 Bos taurus
420558 Gallus gallus
100518921 Sus scrofa
100009040 Oryctolagus cuniculus
100061625 Equus caballus
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