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CDK6 antibody (AA 3-99)

CDK6 Reactivity: Human WB, IF, ELISA, IHC (p), PLA Host: Mouse Monoclonal 8H4 unconjugated
Catalog No. ABIN560298
  • Target See all CDK6 Antibodies
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Binding Specificity
    • 22
    • 21
    • 14
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-99
    Reactivity
    • 126
    • 49
    • 26
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 110
    • 16
    Mouse
    Clonality
    • 100
    • 26
    Monoclonal
    Conjugate
    • 67
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CDK6 antibody is un-conjugated
    Application
    • 75
    • 37
    • 30
    • 27
    • 27
    • 23
    • 22
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant CDK6.
    Sequence
    KDGLCRADQQ YECVAEIGEG AYGKVFKARD LKNGGRFVAL KRVRVQTGEE GMPLSTIREV AVLRHLETFE HPNVVRLFDV CTVSRTDRET KLTLVFE
    Cross-Reactivity
    Human, Rat
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    CDK6 (NP_001250, 3 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    8H4
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Erdmann, Kaulke, Rieger, Salomo, Wirth, Fuessel: "MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells." in: Journal of cancer research and clinical oncology, Vol. 142, Issue 11, pp. 2249-61, (2016) (PubMed).

    Quinn, Glassford, Percy, Munson, Marafioti, Rodriguez-Justo, Yong: "APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status." in: Blood, Vol. 117, Issue 3, pp. 890-901, (2011) (PubMed).

  • Target
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Alternative Name
    CDK6 (CDK6 Products)
    Synonyms
    CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
    Background
    Full Gene Name: cyclin-dependent kinase 6
    Synonyms: MGC59692,PLSTIRE,STQTL11
    Gene ID
    1021
    NCBI Accession
    NM_001259
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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