CDK6 antibody (AA 3-99)

Catalog No. ABIN560298

Cited in 2+ publications. The Mouse Monoclonal anti-CDK6 antibody (Clone 8H4) (ABIN560298) specifically detects CDK6 in WB, ELISA, IF, IHC (p) and PLA. The antibody is reactive with Human samples.

Quick Overview for CDK6 antibody (AA 3-99) (ABIN560298)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

Clone: 8H4

Product Details anti-CDK6 Antibody

Binding Specificity: AA 3-99

Purpose: Mouse monoclonal antibody raised against a partial recombinant CDK6.

Sequence: KDGLCRADQQ YECVAEIGEG AYGKVFKARD LKNGGRFVAL KRVRVQTGEE GMPLSTIREV AVLRHLETFE HPNVVRLFDV CTVSRTDRET KLTLVFE

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CDK6 (NP_001250, 3 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CDK6 antibody (ABIN560298)

Erdmann, Kaulke, Rieger, Salomo, Wirth, Fuessel: "MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells." in: Journal of cancer research and clinical oncology, Vol. 142, Issue 11, pp. 2249-61, (2016) (PubMed).

Quinn, Glassford, Percy, Munson, Marafioti, Rodriguez-Justo, Yong: "APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status." in: Blood, Vol. 117, Issue 3, pp. 890-901, (2011) (PubMed).

Target Details for CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Alternative Name: CDK6

Background: Full Gene Name: cyclin-dependent kinase 6
Synonyms: MGC59692,PLSTIRE,STQTL11

Gene ID: 1021

NCBI Accession: NM_001259

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases