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Browse our anti-FOXO3 (FOXO3) Antibodies

Full name:
anti-Forkhead Box O3 Antibodies (FOXO3)
On www.antibodies-online.com are 298 Forkhead Box O3 (FOXO3) Antibodies from 32 different suppliers available. Additionally we are shipping FOXO3 Kits (30) and FOXO3 Proteins (8) and many more products for this protein. A total of 349 FOXO3 products are currently listed.
Synonyms:
1110048B16Rik, 2010203A17Rik, AF6q21, C76856, Fkhr2, Fkhrl1, FKHRL1P2, foxO, FOXO-3, FOXO2, foxO3, FoxO3A, wu:fb50g02, wu:fi33f07, xfoxo3, zgc:92176
list all antibodies Gene Name GeneID UniProt
FOXO3 2309 O43524
FOXO3 56484 Q9WVH4
FOXO3 294515  

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Most Popular Reactivities for anti-FOXO3 (FOXO3) Antibodies

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anti-Human FOXO3 Antibodies:

anti-Mouse (Murine) FOXO3 Antibodies:

anti-Rat (Rattus) FOXO3 Antibodies:

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Top referenced anti-FOXO3 Antibodies

  1. Human Polyclonal FOXO3 Primary Antibody for IF, IHC (p) - ABIN658087 : Zhuo, Niu, Chen, Xin, Guo, Mao: Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN658087

  2. Human Polyclonal FOXO3 Primary Antibody for IHC (p), WB - ABIN657229 : Tudzarova, Trotter, Wollenschlaeger, Mulvey, Godovac-Zimmermann, Williams, Stoeber: Molecular architecture of the DNA replication origin activation checkpoint. in The EMBO journal 2010 (PubMed)
    Show all 4 references for ABIN657229

  3. Human Polyclonal FOXO3 Primary Antibody for EIA, WB - ABIN783540 : Anderson, Viars, Czekay, Cavenee, Arden: Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN783540

  4. Human Polyclonal FOXO3 Primary Antibody for IHC, ELISA - ABIN1533051 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1533051

  5. Human Polyclonal FOXO3 Primary Antibody for IHC (p), IP - ABIN152044 : Yuan, Luo, Liu, Lou: Regulation of SIRT1 activity by genotoxic stress. in Genes & development 2012 (PubMed)

  6. Human Polyclonal FOXO3 Primary Antibody for IF (p), IHC (p) - ABIN684718 : Morales, Abrigo, Acuña, Santos, Bader, Brandan, Simon, Olguin, Cabrera, Cabello-Verrugio: Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas. in Disease models & mechanisms 2016 (PubMed)

  7. Human Polyclonal FOXO3 Primary Antibody for ELISA, WB - ABIN185248 : Brunet, Bonni, Zigmond, Lin, Juo, Hu, Anderson, Arden, Blenis, Greenberg: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. in Cell 1999 (PubMed)

  8. Cow (Bovine) Polyclonal FOXO3 Primary Antibody for EIA, WB - ABIN782940 : Stefani, Markus, Lin, Pinese, Dawes, Morris: The effect of resveratrol on a cell model of human aging. in Annals of the New York Academy of Sciences 2007 (PubMed)

  9. Cow (Bovine) Polyclonal FOXO3 Primary Antibody for WB - ABIN2780366 : Pew, Zou, Brickley, Conzen: Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway. in Endocrinology 2008 (PubMed)

More Antibodies against FOXO3 Interaction Partners

Zebrafish Forkhead Box O3 (FOXO3) interaction partners

  1. This study provided novel evidence of FoxO3a in the embryonic neurodevelopment from zebrafish to other mammals.

Human Forkhead Box O3 (FOXO3) interaction partners

  1. MCT1 (show CMA1 Antibodies) expression associates with the SCC (show CYP11A1 Antibodies) type and metastatic behavior of AC, whereas MCT4 (show SLC16A4 Antibodies) expression concomitantly increases from in situ SCC (show CYP11A1 Antibodies) to invasive SCC (show CYP11A1 Antibodies) and is significantly associated with the AC type. Consistently, FOXM1 (show FOXM1 Antibodies) expression is statistically associated with MCT1 (show CMA1 Antibodies) positivity in SCC (show CYP11A1 Antibodies), whereas the expression of FOXO3a, a FOXM1 (show FOXM1 Antibodies) functional antagonist, is linked to MCT1 (show CMA1 Antibodies) negativity

  2. SUN inhibits TNBC MDA-MB231 cell proliferation through activation of FOXO3a expression

  3. Results suggest that miR-155 down-regulates polymerase delta by targeting the transcription factor FOXO3a, thereby inhibiting the transcription of the four polymerase delta subunits, resulting in an increased susceptibility to mutation by suppressing a high-fidelity polymerase and favoring error prone translesion synthesis.

  4. FOXO3 is more active than FOXO1 (show FOXO1 Antibodies) in primitive hematopoietic stem cells; the upstream regulators other than AKT (show AKT1 Antibodies), such as SIRT1 (show SIRT1 Antibodies), maintain nuclear FOXO localization and activity in hematopoietic stem cells.

  5. This work thus demonstrates that S-574 phosphorylation generates a specifically apoptotic form of FOXO3 with decreased transcriptional activity for other well-described FOXO3 functions.

  6. FOXO3a directly interacts with the Par-4 (show PAWR Antibodies) promoter and activates and initiates caspase (show CASP3 Antibodies)-mediated cell death upon Withaferin-A treatment.

  7. Stimulation with H2O2 decreased the phosphorylation of Akt (show AKT1 Antibodies) and FoxO3a, and induced nuclear localization of FoxO3a and apoptosis of H9c2 cells. These effects of H2O2 were abrogated by pretreatment with FGF-2 (show FGF2 Antibodies)

  8. Overexpression of FOXO3A is associated with breast cancer.

  9. Our findings indicate that FOXO3a is a significant factor in EGFR (show EGFR Antibodies) mutation-independent gefitinib resistance and the stemness of lung cancer, and suggest that targeting the NF-kappaB (show NFKB1 Antibodies)/miR (show MLXIP Antibodies)-155/FOXO3a pathway has potential therapeutic value in lung cancer with the acquisition of resistance to EGFR (show EGFR Antibodies)-TKIs.

  10. FOXO3a may play an important role in the intestinal inflammation of patients with UC.

Mouse (Murine) Forkhead Box O3 (FOXO3) interaction partners

  1. Iron-induced skeletal muscle atrophy is suggested to involve the E3 ubiquitin ligase (show MUL1 Antibodies) mediated by the reduction of Akt (show AKT1 Antibodies)-FOXO3a signaling by oxidative stress.

  2. Vesicular stomatitis virus (VSV) infection induced significant up-regulation of miR (show MLXIP Antibodies)-223 in murine macrophages. miR (show MLXIP Antibodies)-223 directly targets FOXO3 to regulate the type I IFN production.

  3. These findings demonstrate that melatonin attenuates cisplatin-induced follicle loss by preventing the phosphorylation of PTEN (show PTEN Antibodies)/AKT (show AKT1 Antibodies)/FOXO3a pathway members; thus, melatonin is a potential therapeutic agent for ovarian protection and fertility preservation during chemotherapy in female cancer patients.

  4. This work thus demonstrates that S-574 phosphorylation generates a specifically apoptotic form of FOXO3 with decreased transcriptional activity for other well-described FOXO3 functions.

  5. SIRT6 (show SIRT6 Antibodies) up-regulates AMP (show TMPRSS5 Antibodies)/ATP and then activates the AMPK (show PRKAA1 Antibodies)-FoxO3alpha axis and further initiates the downstream antioxidant-encoding gene expression, thereby decreasing cellular levels of oxidative stress, and mediating cardioprotection in ischemic heart

  6. Kit ligand (show KITLG Antibodies) regulates the subcellular localization of FOXO3 in the neonatal mouse ovary.

  7. These data suggest a role for FoxO3a in the maintenance of genome integrity in response to DNA damage that is mediated by H2AX via yet unknown mechanisms.

  8. mice. In vitro assays revealed enhanced survival capacity of Myc (show MYC Antibodies)-driven cells lacking FoxO3, but no change in cell cycling was detected

  9. Results point to an antioxidant defense mechanism presented by Sirt3 (show SIRT3 Antibodies) through the activation of Foxo3a, in microglia

  10. Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 (show D4S234E Antibodies) and CDK2 (show CDK2 Antibodies).

Pig (Porcine) Forkhead Box O3 (FOXO3) interaction partners

  1. These results indicate that myostatin (show MSTN Antibodies) mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 and glucocorticoid receptor (show NR3C1 Antibodies) binding to its promoter.

  2. In granulosa cells, cell death is induced by transfection of FOXO3. FOXO3 mRNA in granulosa cells increases during atresia; FOXO3 protein is abundant in granulosa cells of early atretic follicles. (FOXO3 AA sequence homology with human/mouse FOXO3)

  3. PTEN (show PTEN Antibodies), FOXO3A and PKB (show AKT1 Antibodies) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

  4. Primordial oocytes are dormant in prepubertal pigs by a FOXO3-related mechanism to establish a nongrowing oocyte pool in the ovary, and that a transient knockdown of the FOXO3 activates the primordial oocytes to enter the growth phase.

  5. FoxO3a was localized in the granulosa cells of follicles at all stages and was extensively localized in the cytoplasma of the luteinized granulosa cells of corpora lutea

Cow (Bovine) Forkhead Box O3 (FOXO3) interaction partners

  1. NO/protein kinase (show CDK7 Antibodies) G (PKG (show PRKG1 Antibodies))-dependent downregulation of PGC-1 alpha (show PPARGC1A Antibodies) and the ROS (show ROS1 Antibodies) detoxification system in endothelial cells are mediated by the PI3K/Akt (show AKT1 Antibodies) signaling pathway and subsequent inactivation of transcription factor Foxo3a.

  2. FOXO is a key regulator of ROS (show ROS1 Antibodies)-induced apoptosis in mammalian cells.

FOXO3 Antigen Profile

Antigen Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with FOXO3

  • forkhead box O3 (FOXO3) antibody
  • forkhead box O3A (foxo3a) antibody
  • forkhead box O3 (foxo3) antibody
  • forkhead box O3 (foxO3) antibody
  • forkhead box O3 (Foxo3) antibody
  • 1110048B16Rik antibody
  • 2010203A17Rik antibody
  • AF6q21 antibody
  • C76856 antibody
  • Fkhr2 antibody
  • Fkhrl1 antibody
  • FKHRL1P2 antibody
  • foxO antibody
  • FOXO-3 antibody
  • FOXO2 antibody
  • foxO3 antibody
  • FoxO3A antibody
  • wu:fb50g02 antibody
  • wu:fi33f07 antibody
  • xfoxo3 antibody
  • zgc:92176 antibody

Protein level used designations for anti-Forkhead Box O3 (FOXO3) Antibodies

forkhead box O3 , forkhead box O3A , fb50g02 , fi33f07 , forkhead box O protein , forkhead box protein O3-like , forkhead box protein O3 , forkhead homolog (rhabdomyosarcoma) like 1 , forkhead in rhabdomyosarcoma-like 1 , forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1 , forkhead box O3a , forkhead protein FKHR2 , xFoxO3 , forkhead box O3A transcription factor

GENE ID SPECIES
445015 Canis lupus familiaris
494532 Danio rerio
462921 Pan troglodytes
700731 Macaca mulatta
100066558 Equus caballus
100125025 Xenopus (Silurana) tropicalis
100303473 Saccoglossus kowalevskii
100406446 Callithrix jacchus
100451077 Pongo abelii
100600519 Nomascus leucogenys
2309 Homo sapiens
56484 Mus musculus
444992 Xenopus laevis
481954 Canis lupus familiaris
733621 Sus scrofa
294515 Rattus norvegicus
535530 Bos taurus
100713179 Cavia porcellus
421769 Gallus gallus
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