FOXO3 antibody (N-Term)
Quick Overview for FOXO3 antibody (N-Term) (ABIN2780366)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- N-Term
-
Purpose
- FOXO3 Antibody - N-terminal region
-
Sequence
- MAEAPASPAP LSPLEVELDP EFEPQSRPRS CTWPLQRPEL QASPAKPSGE
-
Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 75%
-
Characteristics
- This is a rabbit polyclonal antibody against FOXO3. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO3
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100919
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- prevent freeze-thaw cycles
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- FOXO3 (Forkhead Box O3 (FOXO3))
-
Alternative Name
- FOXO3
-
Background
-
Background Information: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Gene Name: Forkhead box O3
Alternative Symbols: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2
Protein Name: Forkhead box protein O3
-
Molecular Weight
- 71kDa
-
Gene ID
- 2309
-
NCBI Accession
- NP_001446
-
UniProt
- O43524
-
Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
-