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Browse our anti-Retinoblastoma 1 (RB1) Antibodies

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anti-Retinoblastoma 1 Antibodies (RB1)
On are 591 Retinoblastoma 1 (RB1) Antibodies from 29 different suppliers available. Additionally we are shipping Retinoblastoma 1 Kits (20) and Retinoblastoma 1 Proteins (12) and many more products for this protein. A total of 693 Retinoblastoma 1 products are currently listed.
OSRC, P105-RB, PP110, pRb, Rb, Rb-1, RB1, RB11, zgc:154147

All available anti-Retinoblastoma 1 Antibodies

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Top referenced anti-Retinoblastoma 1 Antibodies

  1. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358211 : Yan, Bell, Breeden, Ellington: Aptamers: prospects in therapeutics and biomedicine. in Frontiers in bioscience : a journal and virtual library 2005 (PubMed)
    Show all 5 references for ABIN358211

  2. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358214 : Wagner, Roemer: Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. in Biochemical pharmacology 2005 (PubMed)
    Show all 5 references for ABIN358214

  3. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358212 : Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 (PubMed)
    Show all 5 references for ABIN358212

  4. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358210 : Lieman, Worley, Harbour: Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN358210

  5. Human Polyclonal Retinoblastoma 1 Primary Antibody for DB, IHC (p) - ABIN389644 : Budde, Schneiderhan-Marra, Petersen, Brüne: Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1). in Oncogene 2005 (PubMed)
    Show all 2 references for ABIN389644

  6. Human Monoclonal Retinoblastoma 1 Primary Antibody for FACS, IHC (fro) - ABIN180306 : Bártek, Vojt?sek, Grand, Gallimore, Lane: Cellular localization and T antigen binding of the retinoblastoma protein. in Oncogene 1992 (PubMed)
    Show all 2 references for ABIN180306

  7. Human Polyclonal Retinoblastoma 1 Primary Antibody for FACS, IHC (p) - ABIN652516 : Connell-Crowley, Harper, Goodrich: Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. in Molecular biology of the cell 1997 (PubMed)
    Show all 2 references for ABIN652516

  8. Chicken Polyclonal Retinoblastoma 1 Primary Antibody for WB - ABIN2777807 : Dasgupta, Sun, Wang, Fusaro, Betts, Padmanabhan, Sebti, Chellappan: Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis. in Molecular and cellular biology 2004 (PubMed)

More Antibodies against Retinoblastoma 1 Interaction Partners

Human Retinoblastoma 1 (RB1) interaction partners

  1. Statistically significant correlations were found only in Morbus Bowen (preinvasive cutaneous carcinoma) between parameters HPV-p53 (show TP53 Antibodies), p53 (show TP53 Antibodies)-pRb and p53 (show TP53 Antibodies)-p16 (show CDKN2A Antibodies).

  2. the previously reported CGI/retrocopy in intron 2 of the RB1 gene (PPP1R26P1) as well as the CGI associated with the retrocopy RPS2P32 identified in this study carry a maternal methylation imprint. In conclusion, these findings shed light on the evolutionary dynamics and constraints of DNA methylation (show HELLS Antibodies).

  3. Suppression of tumorigenesis by CADM1 (show CADM1 Antibodies) may be mediated by the Rb-E2F1 (show E2F1 Antibodies) pathway.

  4. The type and frequency of RB1 mutations in retinoblastoma patients were determined. Those who have deletions in the RB1 gene are at increased risk of chemoresistance and at higher risk of requiring enucleation.

  5. Epstein-Barr virus (EBV) infection is inversely correlated with pRb in Hodgkin/Reed-Sternberg (H/RS) cells in Classic Hodgkin lymphoma (cHL (show CHRDL1 Antibodies)).

  6. we investigated how Rb is integrated to control bladder cancer progression through E2F3 and p53 (show TP53 Antibodies) regulation. The results exhibit that Rb expression is lower in patients with bladder tumor, while E2F3 level is high. Rb knockdown enhanced bladder tumor cell proliferation and migration, aggravated with p53 (show TP53 Antibodies) silence.

  7. Data suggest that gamma-tocotrienol delays cellular senescence of cultured diploid fibroblasts by regulating the cell cycle through down-regulation of expression of p16-INK4a (CDKN2A/cyclin dependent kinase inhibitor 2A (show CDKN2A Antibodies)) mRNA, of expression/phosphorylation of retinoblastoma protein (RB1), and of expression of cyclin D1 (CCND1 (show CCND1 Antibodies)).

  8. TP53 (show TP53 Antibodies) and RB1 mutations seem to be restricted to high-risk/malignant gastrointestinal stromal tumors and occur at an equal although relatively low frequency.

  9. Increased the expression of tumor suppressor genes such as Cdkn2A (show CDKN2A Antibodies), Rb1 and p53 (show TP53 Antibodies).

  10. By targeting genes involved in controlling pRb/E2F1 (show E2F1 Antibodies) activity, miR (show MLXIP Antibodies)-449a regulates cell cycle progression and apoptosis and consequently enhances the radiosensitivity of PC-3 (show PCSK1 Antibodies) cells. Thus, miR (show MLXIP Antibodies)-449a, as a miRNA component of the Rb pathway, promotes the radiosensitivity of PC-3 (show PCSK1 Antibodies) cells through regulating pRb/E2F1 (show E2F1 Antibodies).

Mouse (Murine) Retinoblastoma 1 (RB1) interaction partners

  1. Findings implicate Rb1 in the regulation of the THO ribonucleoprotein complex.

  2. contribution of these precursors to the Rb(+/-) adipose phenotype is driven, at least in part, by interaction with BMP7 (show BMP7 Antibodies) pathway

  3. Identify Dyrk1a (show DYRK1A Antibodies) as a novel negative regulator of D-cyclin (show PCNA Antibodies)-mediated Rb1/E2f (show E2F1 Antibodies)-signalling. As dysregulation of this pathway with impaired cardiomyocyte proliferation leads to cardiomyopathy.

  4. Expression of Kv10.1 (show KCNG3 Antibodies) driven by phosphorylated Rb/E2F1 (show E2F1 Antibodies) contributes to G2/M progression of cancer and non-transformed cells.

  5. These findings establish that Rb1 and Skp2 deletions are synthetic lethal and suggest how this lethal relationship might be circumvented, which could help design better therapies for pRb (show PGR Antibodies)-deficient cancer.

  6. Results indicate that Rb and p53 (show TP53 Antibodies) not only function as tumor suppressors in response to carcinogenic injury, but also in response to non-carcinogenic injury.

  7. Suggest that a principal role for RB1 in development is coordinating the events required for terminal differentiation of erythroid cells.

  8. data also suggest that Rb1 loss is not sufficient to transform post-germinal center B cells and that additional, specific mutations are likely required to cooperate with Rb1 loss to induce malignant transformation.

  9. propose that by repressing Pak1 expression, Rb prevents Rac1 hyperactivity usually associated with cancer and related to cytoskeletal derangements that disrupt cell adhesion, consequently enhancing cancer cell migratory capacity

  10. Data (including data from studies in knockout/transgenic mice) suggest CDKN1B (show CDKN1B Antibodies)-RB1-E2F1 (show E2F1 Antibodies) (cyclin-dependent kinase inhibitor 1B (show CDKN1B Antibodies)-RB1-E2F (show E2F1 Antibodies) transcription 1) pathway is essential for SSC (show CYP11A1 Antibodies) (spermatogonial stem cell) self-renewal/protection against DNA damage.

Zebrafish Retinoblastoma 1 (RB1) interaction partners

  1. Our results indicate that Rb-Raf-1 (show RAF1 Antibodies) interaction plays an important role in spontaneous hair cell regeneration in zebrafish

  2. our analysis of zebrafish rb1 mutants reveals a previously unknown yet critical role for rb1 during retinotectal tract development and visual function.

  3. Zebrafish usp39 (show USP37 Antibodies) regulates embryonic pituitary homeostasis by targeting rb1 and e2f4 (show E2F4 Antibodies) expression, respectively, contributing to increased adenohypophyseal sensitivity to these altered cell cycle regulators

Retinoblastoma 1 (RB1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Alternative names and synonyms associated with Retinoblastoma 1 (RB1)

  • retinoblastoma 1 (including osteosarcoma) (RB1) antibody
  • retinoblastoma 1 (RB1) antibody
  • Retinoblastoma-associated protein (rb) antibody
  • retinoblastoma 1 (Rb1) antibody
  • retinoblastoma 1 (rb1) antibody
  • OSRC antibody
  • P105-RB antibody
  • PP110 antibody
  • pRb antibody
  • Rb antibody
  • Rb-1 antibody
  • RB1 antibody
  • RB11 antibody
  • zgc:154147 antibody

Protein level used designations for anti-Retinoblastoma 1 (RB1) Antibodies

retinoblastoma 1 (including osteosarcoma) , retinoblastoma protein 1 , retinoblastoma-associated protein , Retinoblastoma-associated protein , retinoblastoma 1 , retinoblastoma-associated protein-like , retinoblastoma suspectibility protein , pp105 , retinoblastoma protein , Retinoblastoma 1 (including osteosarcoma) , pRb , rb , p104 , spc , retinoblastoma, susceptibility

449604 Pan troglodytes
452715 Pan troglodytes
704871 Macaca mulatta
100217687 Taeniopygia guttata
100380330 Salmo salar
100397928 Callithrix jacchus
5925 Homo sapiens
19645 Mus musculus
476915 Canis lupus familiaris
100057080 Equus caballus
24708 Rattus norvegicus
386582 Gallus gallus
777733 Danio rerio
534712 Bos taurus
100716297 Cavia porcellus
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