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Browse our anti-Retinoblastoma 1 (RB1) Antibodies

Full name:
anti-Retinoblastoma 1 Antibodies (RB1)
On www.antibodies-online.com are 531 Retinoblastoma 1 (RB1) Antibodies from 29 different suppliers available. Additionally we are shipping Retinoblastoma 1 Kits (19) and Retinoblastoma 1 Proteins (10) and many more products for this protein. A total of 630 Retinoblastoma 1 products are currently listed.
Synonyms:
OSRC, P105-RB, PP110, pRb, Rb, Rb-1, RB1, RB11, zgc:154147

Most Popular Reactivities for anti-Retinoblastoma 1 (RB1) Antibodies

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anti-Human Retinoblastoma 1 Antibodies:

anti-Mouse (Murine) Retinoblastoma 1 Antibodies:

anti-Rat (Rattus) Retinoblastoma 1 Antibodies:

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Top referenced anti-Retinoblastoma 1 Antibodies

  1. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358212 : Yan, Bell, Breeden, Ellington: Aptamers: prospects in therapeutics and biomedicine. in Frontiers in bioscience : a journal and virtual library 2005 (PubMed)
    Show all 5 references for ABIN358212

  2. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358214 : Wagner, Roemer: Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. in Biochemical pharmacology 2005 (PubMed)
    Show all 5 references for ABIN358214

  3. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358211 : Roesch, Becker, Meyer, Hafner, Wild, Landthaler, Vogt: Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 (PubMed)
    Show all 5 references for ABIN358211

  4. Human Polyclonal Retinoblastoma 1 Primary Antibody for EIA, IHC (p) - ABIN358210 : Lieman, Worley, Harbour: Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN358210

  5. Human Polyclonal Retinoblastoma 1 Primary Antibody for DB, IHC (p) - ABIN389644 : Budde, Schneiderhan-Marra, Petersen, Brüne: Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1). in Oncogene 2005 (PubMed)
    Show all 2 references for ABIN389644

  6. Human Polyclonal Retinoblastoma 1 Primary Antibody for FACS, IHC (p) - ABIN652516 : Connell-Crowley, Harper, Goodrich: Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. in Molecular biology of the cell 1997 (PubMed)
    Show all 2 references for ABIN652516

  7. Human Monoclonal Retinoblastoma 1 Primary Antibody for FACS, IHC (fro) - ABIN180306 : Bártek, Vojt?sek, Grand, Gallimore, Lane: Cellular localization and T antigen binding of the retinoblastoma protein. in Oncogene 1992 (PubMed)
    Show all 2 references for ABIN180306

  8. Chicken Polyclonal Retinoblastoma 1 Primary Antibody for WB - ABIN2777807 : Dasgupta, Sun, Wang, Fusaro, Betts, Padmanabhan, Sebti, Chellappan: Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis. in Molecular and cellular biology 2004 (PubMed)

More Antibodies against Retinoblastoma 1 Interaction Partners

Human Retinoblastoma 1 (RB1) interaction partners

  1. This review focuses on the ability of pRB to control nucleosome/chromatin structures via physical interactions with histone modifiers and chromatin factors and describes cancer therapies based on targeting these protein factors.

  2. CTDSPL (show CTDSPL Antibodies) and Rb directly interact and can be involved in the common mechanism of cell cycle regulation.

  3. We further discuss how dysfunction in the p53 (show TP53 Antibodies)- and/or Rb-mediated mechanosignaling pathways is potentially involved in cancer progression. These pathways might provide good targets for developing anticancer therapies

  4. Chk1's (show CHEK1 Antibodies) expression is controlled by p53 (show TP53 Antibodies) and RB/E2F1 (show E2F1 Antibodies) at the transcriptional level.

  5. the functional association of BLCAP (show BLCAP Antibodies) and Rb1 might play important roles in proliferation and apoptosis of HeLa cells.

  6. Results suggest that retinoblastoma 1 (RB1) promoter methylation may be associated with GC and H. pylori infection.

  7. We also observed that a dedifferentiated osteosarcomas (OS)harboring MDM2 (show MDM2 Antibodies) amplification did not carry any other mutations. This study suggests that bone oncogenesis driven by TP53 (show TP53 Antibodies) or RB1 mutations occurs on a background of relative genetic stability and that the dedifferentiated OS subtype represents a clinico-pathological entity with distinct oncogenic mechanisms

  8. The two most frequently mutated genes were TP53 (show TP53 Antibodies) (86%) and RB1 (58%); other frequently mutated genes (>10% patients) were involved in epigenetic regulation as well as the mTOR (show FRAP1 Antibodies) pathway.We found that small-cell lung cancer tumors harboring no mutation in RB1 had a poor response to chemotherapy.

  9. Expression of Kv10.1 (show KCNH1 Antibodies) driven by phosphorylated Rb/E2F1 (show E2F1 Antibodies) contributes to G2/M progression of cancer and non-transformed cells.

  10. In pancreatic neoplasms, miR (show MLXIP Antibodies)-137 targets KDM4A (show KDM4A Antibodies) mRNA during Ras-induced senescence and activates both p53 (show TP53 Antibodies) and retinoblastoma (pRb) tumor suppressor pathways.

Mouse (Murine) Retinoblastoma 1 (RB1) interaction partners

  1. Expression of Kv10.1 (show KCNG3 Antibodies) driven by phosphorylated Rb/E2F1 (show E2F1 Antibodies) contributes to G2/M progression of cancer and non-transformed cells.

  2. These findings establish that Rb1 and Skp2 deletions are synthetic lethal and suggest how this lethal relationship might be circumvented, which could help design better therapies for pRb (show PGR Antibodies)-deficient cancer.

  3. Results indicate that Rb and p53 (show TP53 Antibodies) not only function as tumor suppressors in response to carcinogenic injury, but also in response to non-carcinogenic injury.

  4. Suggest that a principal role for RB1 in development is coordinating the events required for terminal differentiation of erythroid cells.

  5. data also suggest that Rb1 loss is not sufficient to transform post-germinal center B cells and that additional, specific mutations are likely required to cooperate with Rb1 loss to induce malignant transformation.

  6. propose that by repressing Pak1 expression, Rb prevents Rac1 hyperactivity usually associated with cancer and related to cytoskeletal derangements that disrupt cell adhesion, consequently enhancing cancer cell migratory capacity

  7. Data (including data from studies in knockout/transgenic mice) suggest CDKN1B (show CDKN1B Antibodies)-RB1-E2F1 (show E2F1 Antibodies) (cyclin-dependent kinase inhibitor 1B (show CDKN1B Antibodies)-RB1-E2F (show E2F1 Antibodies) transcription 1) pathway is essential for SSC (show CYP11A1 Antibodies) (spermatogonial stem cell) self-renewal/protection against DNA damage.

  8. A model suited to determine the cellular function of the alternative Rb1 transcript.

  9. data indicate that Pten (show PTEN Antibodies) deletion in osteoblast precursors is sufficient to promote frequent adipogenic, but only rare osteogenic tumors. Rb1 hetero- or homo-zygous co-deletion greatly increases the incidence and the rapidity of onset of adipogenic tumors.

  10. we have discovered a novel role of Rb1 in regulating the entry of primordial oocytes into the pool of growing follicles and signaling between the oocyte and granulosa cells during the protracted process of oocyte growth

Zebrafish Retinoblastoma 1 (RB1) interaction partners

  1. Our results indicate that Rb-Raf-1 (show RAF1 Antibodies) interaction plays an important role in spontaneous hair cell regeneration in zebrafish

  2. our analysis of zebrafish rb1 mutants reveals a previously unknown yet critical role for rb1 during retinotectal tract development and visual function.

  3. Zebrafish usp39 (show USP37 Antibodies) regulates embryonic pituitary homeostasis by targeting rb1 and e2f4 (show E2F4 Antibodies) expression, respectively, contributing to increased adenohypophyseal sensitivity to these altered cell cycle regulators

Retinoblastoma 1 (RB1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Alternative names and synonyms associated with Retinoblastoma 1 (RB1)

  • retinoblastoma 1 (including osteosarcoma) (RB1) antibody
  • retinoblastoma 1 (RB1) antibody
  • Retinoblastoma-associated protein (rb) antibody
  • retinoblastoma 1 (Rb1) antibody
  • retinoblastoma 1 (rb1) antibody
  • OSRC antibody
  • P105-RB antibody
  • PP110 antibody
  • pRb antibody
  • Rb antibody
  • Rb-1 antibody
  • RB1 antibody
  • RB11 antibody
  • zgc:154147 antibody

Protein level used designations for anti-Retinoblastoma 1 (RB1) Antibodies

retinoblastoma 1 (including osteosarcoma) , retinoblastoma protein 1 , retinoblastoma-associated protein , Retinoblastoma-associated protein , retinoblastoma 1 , retinoblastoma-associated protein-like , retinoblastoma suspectibility protein , pp105 , retinoblastoma protein , Retinoblastoma 1 (including osteosarcoma) , pRb , rb , p104 , spc , retinoblastoma, susceptibility

GENE ID SPECIES
449604 Pan troglodytes
452715 Pan troglodytes
704871 Macaca mulatta
100217687 Taeniopygia guttata
100380330 Salmo salar
100397928 Callithrix jacchus
5925 Homo sapiens
19645 Mus musculus
476915 Canis lupus familiaris
100057080 Equus caballus
24708 Rattus norvegicus
386582 Gallus gallus
777733 Danio rerio
534712 Bos taurus
100716297 Cavia porcellus
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