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Retinoblastoma 1 antibody (pSer612)

RB1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB7659 unconjugated
Catalog No. ABIN389643
  • Target See all Retinoblastoma 1 (RB1) Antibodies
    Retinoblastoma 1 (RB1)
    Binding Specificity
    • 32
    • 31
    • 29
    • 24
    • 23
    • 22
    • 20
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer612
    Reactivity
    • 290
    • 113
    • 95
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 251
    • 42
    Rabbit
    Clonality
    • 237
    • 56
    Polyclonal
    Conjugate
    • 146
    • 19
    • 17
    • 16
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoblastoma 1 antibody is un-conjugated
    Application
    • 222
    • 132
    • 114
    • 80
    • 79
    • 41
    • 39
    • 35
    • 28
    • 19
    • 19
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This RB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB.
    Clone
    RB7659
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RB1 Primary Antibody
  • Application Notes
    WB = 1:1000, IHC (p) = 1:50-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.38 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Rizzolio, Lucchetti, Caligiuri, Marchesi, Caputo, Klein-Szanto, Bagella, Castronovo, Giordano: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).

  • Target
    Retinoblastoma 1 (RB1)
    Alternative Name
    RB (RB1 Products)
    Synonyms
    OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
    Background
    Synonyms: Retinoblastoma-associated protein, PP110, P105-RB, RB, RB1,
    Molecular Weight
    106159 DA
    Gene ID
    5925
    UniProt
    P06400
    Pathways
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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