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Retinoblastoma 1 antibody (C-Term)

RB1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB20715 unconjugated
Catalog No. ABIN652516
  • Target See all Retinoblastoma 1 (RB1) Antibodies
    Retinoblastoma 1 (RB1)
    Binding Specificity
    • 31
    • 31
    • 29
    • 24
    • 23
    • 22
    • 20
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 858-886, C-Term
    Reactivity
    • 289
    • 113
    • 95
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 250
    • 42
    Rabbit
    Clonality
    • 237
    • 55
    Polyclonal
    Conjugate
    • 145
    • 19
    • 17
    • 16
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoblastoma 1 antibody is un-conjugated
    Application
    • 221
    • 132
    • 113
    • 80
    • 79
    • 41
    • 39
    • 35
    • 28
    • 19
    • 18
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Predicted Reactivity
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1.
    Clone
    RB20715
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RB1 Primary Antibody
  • Application Notes
    WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Retinoblastoma 1 (RB1)
    Alternative Name
    RB1 (RB1 Products)
    Synonyms
    OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
    Background
    RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
    Molecular Weight
    106159
    Gene ID
    5925
    NCBI Accession
    NP_000312
    UniProt
    P06400
    Pathways
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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