Browse our anti-FLASH (CASP8AP2) Antibodies

On are 49 CASP8 Associated Protein 2 (CASP8AP2) Antibodies from 16 different suppliers available. Additionally we are shipping FLASH Kits (7) and many more products for this protein. A total of 59 FLASH products are currently listed.
AA387232, CASP8AP2, CED-4, D4Ertd659e, fc74h10, FLASH, mKIAA1315, RIP25, wu:fc74h10, zgc:113449
list all antibodies Gene Name GeneID UniProt
CASP8AP2 9994 Q9UKL3
CASP8AP2 26885 Q9WUF3
CASP8AP2 313128  

Most Popular Reactivities for anti-FLASH (CASP8AP2) Antibodies

anti-Human FLASH Antibodies:

anti-Mouse (Murine) FLASH Antibodies:

anti-Rat (Rattus) FLASH Antibodies:

All available anti-FLASH Antibodies

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More Antibodies against FLASH Interaction Partners

Human CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. FLASH plays two roles in 3' end processing of histone pre-mRNAs: It interacts with Lsm11 (show LSM11 Antibodies) to form a docking platform for the polyadenylation factors, and it cooperates with SLBP (show SLBP Antibodies) to recruit U7 snRNP (show LSM2 Antibodies) to histone pre-mRNA.

  2. Our results indicate that the APAF1 (show APAF1 Antibodies), BAX (show BAX Antibodies), and FLASH genes not only harbor frameshift mutations but also demonstrate mutational ITH, which together might play a role in the tumorigenesis of CRC (show CALR Antibodies) with MSI (show MSI1 Antibodies)-H by affecting the apoptosis of cancer cells.

  3. High-quality solution NMR structures of three homeodomains from human proteins ALX4 (show ALX4 Antibodies), ZHX1 (show ZHX1 Antibodies) and CASP8AP2 were solved.

  4. the predictive values regarding low expressions of H2AFZ (show H2AFZ Antibodies) and CASP8AP2 and high white blood cell count suggest that these features could help to identify more accurately patients at greater risk of relapse.

  5. ARS2 (show SRRT Antibodies) and CASP8AP2 expressions can precisely predict high-risk of relapse and ALL prognosis.

  6. The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT (show NPAT Antibodies) orthologues, thus acting as a signal targeting proteins to histone locus bodies.

  7. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (show PML Antibodies) bodies.

  8. Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.

  9. FLASH/Lsm11 (show LSM11 Antibodies) complex bind a unique combination of polyadenylation factors

  10. These data demonstrate that methylation within the Casp8AP2 promoter correlates with the development of drug resistance and might serve as a biomarker and treatment target for drug resistance in cancer cells.

Mouse (Murine) CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. the functional interaction of E2A (show TCF3 Antibodies) and FLASH play an important role in cell proliferation and cellular senescence via regulation of p21 (show D4S234E Antibodies) expression in experimental glomerulonephritis.

  2. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (show PML Antibodies) bodies.

FLASH (CASP8AP2) Antigen Profile

Antigen Summary

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with FLASH (CASP8AP2)

  • caspase 8 associated protein 2 (CASP8AP2) antibody
  • CASP8 associated protein 2 (casp8ap2) antibody
  • CASP8 associated protein 2 (CASP8AP2) antibody
  • CASP8 associated protein 2 (LOC100232114) antibody
  • caspase 8 associated protein 2 (Casp8ap2) antibody
  • AA387232 antibody
  • CASP8AP2 antibody
  • CED-4 antibody
  • D4Ertd659e antibody
  • fc74h10 antibody
  • FLASH antibody
  • mKIAA1315 antibody
  • RIP25 antibody
  • wu:fc74h10 antibody
  • zgc:113449 antibody

Protein level used designations for CASP8AP2

CASP8 associated protein 2 , caspase 8 associated protein 2 , CASP8-associated protein 2-like , CASP8-associated protein 2 , FLASH homolog RIP25 , FLICE associated huge , FLICE-associated huge protein , human FLASH

421810 Gallus gallus
472070 Pan troglodytes
541521 Danio rerio
100065766 Equus caballus
100232114 Taeniopygia guttata
702294 Macaca mulatta
100342805 Oryctolagus cuniculus
100401726 Callithrix jacchus
100445558 Pongo abelii
100523759 Sus scrofa
9994 Homo sapiens
26885 Mus musculus
481921 Canis lupus familiaris
505138 Bos taurus
313128 Rattus norvegicus
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