Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

FLT3 Antibodies

(Fms-Related tyrosine Kinase 3 (FLT3))
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jul 2008].
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody (ABIN5518988)

FLT3 Reactivity: Mouse, Rat ELISA, IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody (ABIN1724846)

FLT3 Reactivity: Human IHC, ELISA, WB Host: Mouse Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody (ABIN3030975)

FLT3 Reactivity: Human FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

FLT3 Antibodies by Reactivity

Find FLT3 Antibodies for a variety of species such as anti-Human FLT3, anti-Mouse FLT3, anti-Rat FLT3. The species listed below are among those available. Click on a link to go to the corresponding products.

FLT3 Antibodies by Application

Find FLT3 Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FLT3 Antibodies by Host

Find FLT3 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

FLT3 Antibodies by Binding Specificity

Find FLT3 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FLT3 Antibodies by Clonality

Find available monoclonal or polyclonal FLT3 Antibodies. Click on a link to go to the corresponding products.

FLT3 Antibodies by Clone

Find FLT3 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

FLT3 Antibodies by Conjugate

Find FLT3 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FLT3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN6261770
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IP
Validations
  • (2)
Cat. No. ABIN1302621
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1532045
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN684868
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN6256074
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN391981
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Horse, Human, Monkey, Pig, Rabbit
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048600
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3028662
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA
Validations
  • (2)
Cat. No. ABIN947874
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN359868
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN359869
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3182315
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3184641
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3181448
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IP
Validations
  • (1)
Cat. No. ABIN1302921
Quantity 100 tests
Datasheet Datasheet

Latest Publications for our FLT3 Antibodies

Caldarelli, Müller, Paskowski-Rogacz, Herrmann, Bauer, Koch, Heninger, Krastev, Ding, Kasper, Fischer, Brodhun, Böhmer, Buchholz: "A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling." in: Leukemia, Vol. 27, Issue 12, pp. 2301-10, (2013) (PubMed).

Pereira de Sousa, Berthault, Granato, Dias, Ramond, Kee, Cumano, Vieira: "Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 8, pp. 3822-30, (2012) (PubMed).

How, Sykes, Gupta, Yee, Schimmer, Schuh, Minden, Kamel-Reid, Brandwein: "Influence of FLT3-internal tandem duplication allele burden and white blood cell count on the outcome in patients with intermediate-risk karyotype acute myeloid leukemia." in: Cancer, Vol. 118, Issue 24, pp. 6110-7, (2012) (PubMed).

Williams, Li, Nguyen, Brown, Levis, Small: "Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia." in: Blood, Vol. 120, Issue 15, pp. 3069-79, (2012) (PubMed).

Ninagawa, Murakami, Isobe, Tanaka, Nakagawa, Torihashi: "Mesenchymal stem cells originating from ES cells show high telomerase activity and therapeutic benefits." in: Differentiation; research in biological diversity, Vol. 82, Issue 3, pp. 153-64, (2011) (PubMed).

Arora, Stopp, Böhmer, Schons, Godfrey, Masson, Razumovskaya, Rönnstrand, Tänzer, Bauer, Böhmer, Müller: "Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling." in: The Journal of biological chemistry, Vol. 286, Issue 13, pp. 10918-29, (2011) (PubMed).

Sekine, Kataoka, Fukuyama, Adachi, Davydova, Yamamoto, Kobayashi, Fujihashi, Suzuki, Curiel, Shizukuishi, McGhee, Fujihashi: "A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8126-34, (2008) (PubMed).

Al Shaer, Walsby, Gilkes, Tonks, Walsh, Mills, Burnett, Rowntree: "Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling." in: British journal of haematology, Vol. 141, Issue 4, pp. 483-93, (2008) (PubMed).

Pratz, Levis: "Incorporating FLT3 inhibitors into acute myeloid leukemia treatment regimens." in: Leukemia & lymphoma, Vol. 49, Issue 5, pp. 852-63, (2008) (PubMed).

Ravandi, Jilani, Estey, Kantarjian, Dey, Aguilar, Jitkaroon, Giles, OBrien, Keating, Albitar: "Soluble phosphorylated fms-like tyrosine kinase III. FLT3 protein in patients with acute myeloid leukemia (AML)." in: Leukemia research, Vol. 31, Issue 6, pp. 791-7, (2007) (PubMed).

Aliases for FLT3 Antibodies

fms related tyrosine kinase 3 (FLT3) Antibodies
FMS-like tyrosine kinase 3 (Flt3) Antibodies
fms-related tyrosine kinase 3 (Flt3) Antibodies
fms related tyrosine kinase 3 (Flt3) Antibodies
B230315G04 Antibodies
CD135 Antibodies
Flk-2 Antibodies
FLK-2 Antibodies
Flk2 Antibodies
FLK2 Antibodies
Flt-3 Antibodies
FLT3 Antibodies
Ly72 Antibodies
STK1 Antibodies
wmfl Antibodies
You are here:
Support