Browse our Kallikrein 7 Proteins (KLK7)

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Kallikrein 7 Proteins (KLK7)
On www.antibodies-online.com are 39 Kallikrein 7 (KLK7) Proteins from 14 different suppliers available. Additionally we are shipping Kallikrein 7 Antibodies (112) and Kallikrein 7 Kits (40) and many more products for this protein. A total of 200 Kallikrein 7 products are currently listed.
Synonyms:
hK7, PRSS6, SCCE
list all proteins Gene Name GeneID UniProt
KLK7 23993 Q91VE3
KLK7 292852  
KLK7 5650 P49862

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Kallikrein 7 Proteins (KLK7) by Origin

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Top referenced Kallikrein 7 Proteins

  1. Human Kallikrein 7 Protein expressed in Escherichia coli (E. coli) - ABIN1098690 : Ramani, Kaushal, Haun: Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 2 references for 1098690

  2. Human Kallikrein 7 Protein expressed in Human Cells - ABIN2002805 : Kyriakopoulou, Yousef, Scorilas, Katsaros, Massobrio, Fracchioli, Diamandis: Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer. in Clinical biochemistry 2003 (PubMed)

  3. Human Kallikrein 7 Protein expressed in HEK-293 Cells - ABIN2181442 : Deraison, Bonnart, Lopez, Besson, Robinson, Jayakumar, Wagberg, Brattsand, Hachem, Leonardsson, Hovnanian: LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction. in Molecular biology of the cell 2007 (PubMed)

More Proteins for Kallikrein 7 Interaction Partners

Mouse (Murine) Kallikrein 7 (KLK7) interaction partners

  1. Ablation of KLK7 is not sufficient to rescue the lethal effect of LEKTI-deficiency. Double deficiency of both KLK7 and KLK5 completely rescues Netherton Syndrome-like phenotype.

  2. Higher hK7 expression is associated with cervical adenocarcinomas

  3. Prolonged Klk7 neutralization provokes profound abnormalities in Klk7 function, due to pH-induced high serine protease (show F2 Proteins) activity that degrades lipid processing enzymes and corneodesmosomes proteins.

Human Kallikrein 7 (KLK7) interaction partners

  1. impaired KLK7 secretion from lamellar granules and increased LEKTI expression could underlie the insufficient activation of KLK in atopic dermatitis.

  2. Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells

  3. Korean X-linked ichthyosis (show LBR Proteins) patients exhibited unimpaired skin barrier function and frequent association with the KLK7 gene polymorphism, which may differentiate them from Western X-linked ichthyosis (show LBR Proteins) patients.

  4. This report demonstrates that concurrent loss of KLK5 (show KLK5 Proteins) and KLK7 associates with a poor clinical outcome in Squamous-Cell Carcinoma and could therefore serve as prognostic marker in this disease.

  5. Data demonstrate that elevated levels of KLK6, KLK7 and KLK9 proteins are associated with poor glioblastoma patients survival.

  6. Our findings suggest that serum KLK7 may be a valuable diagnostic biomarker for cervical cancer, and may help to determine the individual prognosis of these patients.

  7. KLK6 (show KLK1 Proteins) and KLK7 mRNA and protein overexpression is directly associated with early-stage ovarian tumors.

  8. Proteolytic cleavage of midkine (show MDK Proteins), CYR61 (show CYR61 Proteins), and tenascin-C (show TNC Proteins) govern the pathophysiological roles of KLK7.

  9. Early-stage oral squamous cell carcinoma and high KLK7 mRNA levels were correlated with the rs10581213(wt/ins + ins/ins (show INS Proteins)) genotypes

  10. These results demonstrate the aberrant expression of KLK7 in colon cancer cells and tissues and its involvement in cell proliferation in vitro and in vivo.

Kallikrein 7 (KLK7) Protein Profile

Protein Summary

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Alternative names and synonyms associated with Kallikrein 7 (KLK7)

  • kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Klk7)
  • kallikrein-related peptidase 7 (Klk7)
  • kallikrein-related peptidase 7 (KLK7)
  • hK7 protein
  • PRSS6 protein
  • SCCE protein

Protein level used designations for Kallikrein 7 Proteins (KLK7)

kallikrein 7 (chymotryptic, stratum corneum) , kallikrein-7 , protease, serine, 6 , serine protease 6 , stratum corneum chymotryptic enzyme , thymopsin , kallikrein related-peptidase 7 (chymotryptic, stratum corneum) , signal protein

GENE ID SPECIES
23993 Mus musculus
292852 Rattus norvegicus
5650 Homo sapiens
100716524 Cavia porcellus
611780 Canis lupus familiaris
100359349 Sus scrofa
506380 Bos taurus
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