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Kallikrein 7 Protein (KLK7) (AA 28-253) (His tag)

KLK7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709811
  • Target See all Kallikrein 7 (KLK7) Proteins
    Kallikrein 7 (KLK7)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-253
    Origin
    • 12
    • 6
    • 3
    Human
    Source
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Kallikrein 7 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    HHSSGLVPRG SHMDDDDKII DGAPCARGSH PWQVALLSGN QLHCGGVLVN ERWVLTAAHC KMNEYTVHLG SDTLGDRRAQ RIKASKSFRH PGYSTQTHVN DLMLVKLNSQ ARLSSMVKKV RLPSRCEPPG TTCTVSGWGT TTSPDVTFPS DLMCVDVKLI SPQDCTKVYK DLLENSMLCA GIPDSKKNAC NGDSGGPLVC RGTLQGLVSW GTFPCGQPND PGVYTQVCKF TKWINDTMKK HR
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product KLK7 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    Kallikrein 7 (KLK7)
    Alternative Name
    KLK7 (KLK7 Products)
    Synonyms
    Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
    Background
    May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
    Molecular Weight
    55.8 kDa
    UniProt
    P49862
    Pathways
    Complement System
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