Kallikrein 7 Protein (KLK7) (His tag)
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- Target See all Kallikrein 7 (KLK7) Proteins
- Kallikrein 7 (KLK7)
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This Kallikrein 7 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Kallikrein 7/KLK7 Protein (His Tag)
- Sequence
- Gln22-Arg249
- Characteristics
- Recombinant Mouse Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Gln22-Arg249 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product KLK7 Protein
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Kallikrein 7 (KLK7) (AA 31-130) protein (GST tag)
KLK7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Kallikrein 7 (KLK7) (Active) protein (His tag)KLK7 Origin: Mouse Host: HEK-293 Cells Recombinant > (71.4+26) % as determined by SDS-PAGE Active
Kallikrein 7 (KLK7) (AA 1-253) protein (GST tag)KLK7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Kallikrein 7 (KLK7)
- Alternative Name
- Kallikrein 7/KLK7 (KLK7 Products)
- Synonyms
- Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
- Background
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Background: Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.
Synonym: Kallikrein-7, Klk7, Serine protease 6, Stratum corneum chymotryptic enzyme, Thymopsin, kallikrein-related peptidase 7, PRSS6, SCCEkallikrein-7,SCCE
- Molecular Weight
- 26.1 kDa
- UniProt
- Q91VE3
- Pathways
- Complement System
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