Kallikrein 7 Products
(Kallikrein 7 (KLK7))
Categories
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011].
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Featured Kallikrein 7 Categories
Kallikrein 7 Antibodies
High quality antibodies with extensive validation data.
Kallikrein 7 ELISA Kits
Reliable ELISA kits for a wide range of species.
Kallikrein 7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Kallikrein 7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN652197
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN652198
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN2855653
Quantity
100 μL
Datasheet
Datasheet
Recommended Kallikrein 7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957256
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962041
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957257
Quantity
96 tests
Datasheet
Datasheet
Recommended Kallikrein 7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308870
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7196671
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320700
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Kallikrein 7 products
: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).: "Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 197, (2016) (PubMed).
: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, (2016) (PubMed).
: "Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17762-75, (2015) (PubMed).
: "Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars." in: Histochemistry and cell biology, Vol. 142, Issue 5, pp. 489-96, (2014) (PubMed).
: "Vaspin inhibits kallikrein 7 by serpin mechanism." in: Cellular and molecular life sciences : CMLS, Vol. 70, Issue 14, pp. 2569-83, (2013) (PubMed).
: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." in: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).
: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." in: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).
: "Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis." in: The Journal of investigative dermatology, Vol. 123, Issue 1, pp. 62-6, (2004) (PubMed).
: "Interaction of alpha-thalassemia with other hemoglobinopathies in the eastern province of Saudi Arabia." in: Birth defects original article series, Vol. 23, Issue 5A, pp. 343-7, (1988) (PubMed).
Synonyms and alternative names related to Kallikrein 7
kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Klk7), kallikrein-related peptidase 7 (Klk7), kallikrein related peptidase 7 (KLK7), kallikrein related peptidase 7 (Klk7), hK7, Prss6, PRSS6, SCCEProtein level used designations for Kallikrein 7
- kallikrein 7 (chymotryptic, stratum corneum)
- kallikrein-7
- protease, serine, 6
- serine protease 6
- stratum corneum chymotryptic enzyme
- thymopsin
- kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
- signal protein
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