Browse our anti-Prothrombin (F2) Antibodies

On www.antibodies-online.com are 228 Coagulation Factor II (thrombin) (F2) Antibodies from 26 different suppliers available. Additionally we are shipping Prothrombin Kits (123) and Prothrombin Proteins (50) and many more products for this protein. A total of 409 Prothrombin products are currently listed.
Synonyms:
AA959438, AI255193, AI327365, C1sa, Cf-2, Cf2, F2, FII, HTRA, HTRA1, prothrombin, PT, RPRGL2, THPH1, thrombin, wu:fb57c10, wu:fd42e09, wu:fd59d01, zgc:66319
list all antibodies Gene Name GeneID UniProt
F2 299602  
F2 14061 P19221
F2 2147 P00734

Most Popular Reactivities for anti-Prothrombin (F2) Antibodies

anti-Rat (Rattus) Prothrombin Antibodies:

anti-Mouse (Murine) Prothrombin Antibodies:

anti-Human Prothrombin Antibodies:

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More Antibodies against Prothrombin Interaction Partners

Zebrafish Coagulation Factor II (thrombin) (F2) interaction partners

  1. Prothrombin morpholino-injected zebrafish embryos yielded an early phenotype exhibiting severe abnormalities that later showed occasional bleeding

Rhesus Monkey Coagulation Factor II (thrombin) (F2) interaction partners

  1. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

Mouse (Murine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.

  2. mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.

  3. Biglycan (show BGN Antibodies) plays a protective role during the progression of atherosclerosis in ApoE (show APOE Antibodies)-deficient mice by inhibiting thrombin generation.

  4. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (show GP1BA Antibodies)-binding and heparin-binding site of thrombin

  5. thrombin/PAR-1 (show MARK2 Antibodies) interaction regulated MCP-1 (show CPT1B Antibodies), TF, MCSF (show CSF1 Antibodies) and IL-6 (show IL6 Antibodies) production.

  6. Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin (show SERPINC1 Antibodies) nanoparticle therapeutics.

  7. Thrombin-PAR1 (show F2R Antibodies) signaling, via nitric oxide and EPCR (show PROCR Antibodies), promotes hematopoietic stem cell (HSC (show FUT1 Antibodies)) mobilization.

  8. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  9. Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase C epsilon.

  10. thrombin/PAR1 (show F2R Antibodies) pathway as a novel target for developing therapeutic strategies to restore synaptic function in the acute phase of ischemic stroke.

Human Coagulation Factor II (thrombin) (F2) interaction partners

  1. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII (show F8 Antibodies) by thrombin has been presented.

  2. These studies clarify the role of PKCdelta (show PKCd Antibodies) in endothelial cell cytoskeleton regulation.

  3. Findings indicate functional effects of thrombin allostery and suggest that individual active site-directed thrombin inhibitors uniquely modulate exosite function.

  4. Acute Coronary Syndrome patients had an enhanced prothrombotic profile, demonstrated by an increased thrombin generation potential, factor XIa and D-dimer levels.

  5. we have found a novel homozygous mutation (p.Tyr510Asp) in the exon 13 of prothrombin gene in a Chinese proband. The mutation is responsible for the prothrombin deficiency reported here. Identification of the prothrombin deficiency in this family allowed mutation-specific prenatal screening.

  6. Individuals suffering from relapsing-remitting and secondary progressive multiple sclerosis had significantly higher prothrombin and factor X levels than healthy donors, whereas levels were unchanged in primary progressive MS and neuromyelitis optica patients.

  7. Prothrombin loading of vascular smooth muscle cell-derived exosomes regulates coagulation and calcification.

  8. Case Reports: prothrombin Padua 2 induces antithrombin (show SERPINC1 Antibodies) resistance and is associated with an increased risk of venous thromboembolism. Codon 596 (CGG) of prothrombin is a hot spot for mutations, which constitute a new and relatively frequent cause of inherited thrombophilia.

  9. Thrombin cleavage sites were mapped to the Duffy binding-like delta1 (DBLdelta1) domain and interdomains 1 and 2 in the PfEMP1 of the parasite line IT4var19.

  10. Furthermore, thrombin treatment of the inflammatory matrix leads to dissolution of HC-HA cable structures and abolishes leukocyte adhesion. These data establish a novel mechanism whereby thrombin cleavage of HC1 regulates the adhesive properties of an inflammatory HA matrix.

Cow (Bovine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. the weaker rapid interaction between prothrombin and membranes is the most important in vivo when considering the activation of prothrombin at the cell surface.

  2. novel pyranosic sulfated (show SULF1 Antibodies) arabinan Ab1 exerts its anticoagulant activity on thrombin by a mechanism different from those found previously for other sulfated (show SULF1 Antibodies) polysaccharides and glycosaminoglycans

  3. Exogenous delivery of thrombin enhances microvascular collateral development in response to ischemic insult, and accelerates tissue reperfusion.

  4. the signaling pathways of MAPK (show MAPK1 Antibodies), MSK1 (show RPS6KA5 Antibodies), and NF-kappaB (show NFKB1 Antibodies) play important roles in thrombin-induced iNOS (show NOS2 Antibodies) expression in alveolar macrophages

  5. High glucose enhances smooth muscle cell responsiveness to thrombin through transcriptional upregulation of PAR-4, mediated via PKC and NFkappaB.

  6. Thrombin induces a sustained contraction in the normal pulmonary artery, by activating PAR(1 (show F2R Antibodies)) and thereby increasing the sensitivity of the myofilament to Ca(2 (show CA2 Antibodies)+).

  7. kinetic and structural analysis of interactions between thrombin and the Factor XIII (show UGDH Antibodies) activation peptide

  8. analysis of staphylocoagulase-mediated bovine prothrombin activation

  9. thrombin and factor Xa (show F10 Antibodies) diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  10. A comparison of recombinant thrombin to bovine thrombin as a hemostatic ancillary in patients undergoing peripheral arterial bypass and arteriovenous graft procedures.

Pig (Porcine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. thrombin stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (show UGDH Antibodies) and by receptor-mediated up-regulation of factor XIII (show UGDH Antibodies) synthesis

  2. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

  3. In conclusion, thrombin activates pro-MMP-2 (show MMP2 Antibodies) in the absence of elevated pro-MMP-2 (show MMP2 Antibodies) expression and secretion in CSMCs, and thrombin induces CSMC mitogenesis involving its action on MMP-2 (show MMP2 Antibodies)

  4. Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (show F2R Antibodies), RhoA (show RHOA Antibodies), and myocardin (show MYOCD Antibodies).

Prothrombin (F2) Antigen Profile

Antigen Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Alternative names and synonyms associated with Prothrombin (F2)

  • coagulation factor II (thrombin) (f2) antibody
  • coagulation factor II (thrombin) (F2) antibody
  • cell division cycle 34 (Cdc34) antibody
  • chymase 1, mast cell (CMA1) antibody
  • coagulation factor II (F2) antibody
  • complement component 1, s subcomponent (C1s) antibody
  • HtrA serine peptidase 1 (Htra1) antibody
  • HtrA serine peptidase 2 (HTRA2) antibody
  • melanoma antigen family B, 17-like (LOC783975) antibody
  • prothrombin-like (LOC100856539) antibody
  • serine protease (HTRA) antibody
  • THROMBIN protein (THROMBIN) antibody
  • AA959438 antibody
  • AI255193 antibody
  • AI327365 antibody
  • C1sa antibody
  • Cf-2 antibody
  • Cf2 antibody
  • F2 antibody
  • FII antibody
  • HTRA antibody
  • HTRA1 antibody
  • prothrombin antibody
  • PT antibody
  • RPRGL2 antibody
  • THPH1 antibody
  • thrombin antibody
  • wu:fb57c10 antibody
  • wu:fd42e09 antibody
  • wu:fd59d01 antibody
  • zgc:66319 antibody

Protein level used designations for F2

prothrombin , cell division cycle 34 homolog , serine protease , ubiquitin-conjugating enzyme Cdc34 , ubiquitin-conjugating enzyme E2 R1 , alpha-chymase , chymase , mast cell chymase , mast cell protease I , coagulation factor 2 , thrombin , prepro-coagulation factor II , prothrombin B-chain , C1 esterase , complement C1s-A subcomponent , complement component 1 subcomponent s-A , complement component C1SA

GENE ID SPECIES
325881 Danio rerio
712729 Macaca mulatta
299602 Rattus norvegicus
490628 Canis lupus familiaris
14061 Mus musculus
29251 Rattus norvegicus
2147 Homo sapiens
280685 Bos taurus
100144442 Sus scrofa
395306 Gallus gallus
100725988 Cavia porcellus
100307041 Ovis aries
50908 Mus musculus
100716225 Cavia porcellus
395990 Gallus gallus
783975 Bos taurus
100856539 Canis lupus familiaris
100008705 Oryctolagus cuniculus
100009146 Oryctolagus cuniculus
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