Prothrombin Products
(Coagulation Factor II (thrombin) (F2))
Categories
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008].
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Featured Prothrombin Categories
Prothrombin Antibodies
High quality antibodies with extensive validation data.
Prothrombin ELISA Kits
Reliable ELISA kits for a wide range of species.
Prothrombin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Prothrombin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP, ELISA, PLA, RNAi
Validations
- (6)
Cat. No.
ABIN560822
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7440125
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7429277
Quantity
100 μL
Datasheet
Datasheet
Recommended Prothrombin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6574219
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965871
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965870
Quantity
96 tests
Datasheet
Datasheet
Recommended Prothrombin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353307
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353309
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7198801
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our Prothrombin products
: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." in: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).: "Thrombin generation in abdominal sepsis is Rho-kinase-dependent." in: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 691-6, (2015) (PubMed).
: "Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection." in: European journal of pharmacology, Vol. 723, pp. 322-9, (2014) (PubMed).
: "Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 5, pp. 708-15, (2013) (PubMed).
: "Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation." in: Toxicology and applied pharmacology, Vol. 272, Issue 1, pp. 86-95, (2013) (PubMed).
: "Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease." in: PLoS ONE, Vol. 6, Issue 1, pp. e15809, (2011) (PubMed).
: "Heparin impairs angiogenesis through inhibition of microRNA-10b." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).
: "Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation and coagulation and ameliorates renal fibrin deposition in a rat model of acute renal failure." in: Shock (Augusta, Ga.), Vol. 32, Issue 6, pp. 626-32, (2009) (PubMed).
: "Microvascular injury and blood-brain barrier leakage in Alzheimer's disease." in: Neurobiology of aging, Vol. 28, Issue 7, pp. 977-86, (2007) (PubMed).
Synonyms and alternative names related to Prothrombin
coagulation factor II, thrombin (F2), coagulation factor II (F2), coagulation factor II (thrombin) (f2), Cf-2, Cf2, F2, FII, prothrombin, PT, RPRGL2, THPH1, thrombin, wu:fb57c10, wu:fd42e09, wu:fd59d01, zgc:66319Protein level used designations for Prothrombin
- prepro-coagulation factor II
- prothrombin
- prothrombin B-chain
- serine protease
- coagulation factor 2
- thrombin
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- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D
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