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Browse our Prothrombin (F2) ELISA Kits

Full name:
Coagulation Factor II (thrombin) ELISA Kits (F2)
On www.antibodies-online.com are 122 Coagulation Factor II (thrombin) (F2) ELISA Kits from 17 different suppliers available. Additionally we are shipping Prothrombin Antibodies (211) and Prothrombin Proteins (55) and many more products for this protein. A total of 396 Prothrombin products are currently listed.
Synonyms:
AA959438, AI255193, AI327365, C1sa, Cf-2, Cf2, F2, FII, HTRA, HTRA1, prothrombin, PT, RPRGL2, THPH1, thrombin, wu:fb57c10, wu:fd42e09, wu:fd59d01, zgc:66319
list all ELISA KIts Gene Name GeneID UniProt
F2 299602  
F2 14061 P19221
F2 2147 P00734

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More ELISA Kits for Prothrombin Interaction Partners

Zebrafish Coagulation Factor II (thrombin) (F2) interaction partners

  1. Prothrombin morpholino-injected zebrafish embryos yielded an early phenotype exhibiting severe abnormalities that later showed occasional bleeding

Rhesus Monkey Coagulation Factor II (thrombin) (F2) interaction partners

  1. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

Mouse (Murine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (show GP1BA ELISA Kits)-binding and heparin-binding site of thrombin

  2. thrombin/PAR-1 (show MARK2 ELISA Kits) interaction regulated MCP-1 (show CPT1B ELISA Kits), TF, MCSF (show CSF1 ELISA Kits) and IL-6 (show IL6 ELISA Kits) production.

  3. Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin (show SERPINC1 ELISA Kits) nanoparticle therapeutics.

  4. Thrombin-PAR1 (show F2R ELISA Kits) signaling, via nitric oxide and EPCR (show PROCR ELISA Kits), promotes hematopoietic stem cell (HSC (show FUT1 ELISA Kits)) mobilization.

  5. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  6. Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 (show CDC25C ELISA Kits) and Ras-associating domains of phospholipase C epsilon (show PLCE1 ELISA Kits).

  7. thrombin/PAR1 (show F2R ELISA Kits) pathway as a novel target for developing therapeutic strategies to restore synaptic function in the acute phase of ischemic stroke.

  8. High Factor IIa expression is associated with multiorgan pathologies in sickle cell disease.

  9. Blockage of thrombin exosites with compounds specific for exosite I (hirudin and HD1 (show HDAC1 ELISA Kits) aptamer) or exosite II (heparin and HD22 aptamer) impaired the COMP (show COMP ELISA Kits)-thrombin interaction, indicating a 2-site binding mechanism.

  10. Whole blood thrombin generation assay is capable of detecting a prothrombotic phenotype in Bmal1 (show ARNTL ELISA Kits)-KO mice.

Human Coagulation Factor II (thrombin) (F2) interaction partners

  1. This study demonstrates that impaired EPCR (show PROCR ELISA Kits) function can be detected by thrombin generation and clot (show TXNDC17 ELISA Kits) lysis assays on cells expressing thrombomodulin (show THBD ELISA Kits) and EPCR (show PROCR ELISA Kits). Deficiency in EPCR (show PROCR ELISA Kits) has procoagulant effects that lead to a delay in clot (show TXNDC17 ELISA Kits) lysis.

  2. Significantly higher serum levels of GP-73 (show GOLM1 ELISA Kits) and PIVKA-II were detected in the hepatocellular carcinoma patients than in controls.

  3. This study investigated whether type 1 diabetes in children is associated with a hypercoagulable state by performing a global function test of coagulation - the thrombin generation assay. The study found only minor changes of thrombin generation in children and adolescents with type 1 diabetes which - in contrast to type 2 diabetes - do not argue for a hypercoagulable state.

  4. These findings suggest a higher prevalence of prothrombin G20210A in patients with atrial fibrillation when compared to healthy controls.

  5. Trauma is associated with coagulation and increased thrombin generation capacity. Evidence of hypercoagulable state was observed in trauma patients.

  6. Boosted thrombin generation shortened the spontaneous plasma clot (show TXNDC17 ELISA Kits) lysis time. The shortening was apparent when the inhibitors of FXIIIa and TAFIa existed. The shortening by thrombin was masked when tissue plasminogen activator (show PLAT ELISA Kits) was added to overcome PAI-1 (show SERPINE1 ELISA Kits).

  7. Signaling levels of thrombin can be generated during moderate hemophilia to sufficiently activate platelets to achieve primary hemostasis, even if fibrin formation remains defective.

  8. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (show GP1BA ELISA Kits)-binding and heparin-binding site of thrombin

  9. serum level differentiates hepatocellular carcinoma from liver cirrhosis, especially when combined with alpha-fetoprotein (show AFP ELISA Kits)

  10. Global prevalence of prothrombin gene mutation G20210A varied from 0 to 15.9% among ethnic groups, with higher rates seen in the thromboembolism affected cohort compared with the unaffected cohort. (Review)

Cow (Bovine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. the weaker rapid interaction between prothrombin and membranes is the most important in vivo when considering the activation of prothrombin at the cell surface.

  2. novel pyranosic sulfated (show SULF1 ELISA Kits) arabinan Ab1 exerts its anticoagulant activity on thrombin by a mechanism different from those found previously for other sulfated (show SULF1 ELISA Kits) polysaccharides and glycosaminoglycans

  3. Exogenous delivery of thrombin enhances microvascular collateral development in response to ischemic insult, and accelerates tissue reperfusion.

  4. the signaling pathways of MAPK (show MAPK1 ELISA Kits), MSK1 (show RPS6KA5 ELISA Kits), and NF-kappaB (show NFKB1 ELISA Kits) play important roles in thrombin-induced iNOS (show NOS2 ELISA Kits) expression in alveolar macrophages

  5. High glucose enhances smooth muscle cell responsiveness to thrombin through transcriptional upregulation of PAR-4, mediated via PKC and NFkappaB.

  6. Thrombin induces a sustained contraction in the normal pulmonary artery, by activating PAR(1 (show F2R ELISA Kits)) and thereby increasing the sensitivity of the myofilament to Ca(2 (show CA2 ELISA Kits)+).

  7. kinetic and structural analysis of interactions between thrombin and the Factor XIII (show UGDH ELISA Kits) activation peptide

  8. analysis of staphylocoagulase-mediated bovine prothrombin activation

  9. thrombin and factor Xa (show F10 ELISA Kits) diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  10. A comparison of recombinant thrombin to bovine thrombin as a hemostatic ancillary in patients undergoing peripheral arterial bypass and arteriovenous graft procedures.

Pig (Porcine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. thrombin stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (show UGDH ELISA Kits) and by receptor-mediated up-regulation of factor XIII (show UGDH ELISA Kits) synthesis

  2. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

  3. In conclusion, thrombin activates pro-MMP-2 (show MMP2 ELISA Kits) in the absence of elevated pro-MMP-2 (show MMP2 ELISA Kits) expression and secretion in CSMCs, and thrombin induces CSMC mitogenesis involving its action on MMP-2 (show MMP2 ELISA Kits)

  4. Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (show F2R ELISA Kits), RhoA (show RHOA ELISA Kits), and myocardin (show MYOCD ELISA Kits).

Prothrombin (F2) Antigen Profile

Antigen Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Alternative names and synonyms associated with Prothrombin (F2)

  • coagulation factor II (thrombin) (f2) Elisa Kit
  • coagulation factor II (thrombin) (F2) Elisa Kit
  • cell division cycle 34 (Cdc34) Elisa Kit
  • chymase 1, mast cell (CMA1) Elisa Kit
  • coagulation factor II (F2) Elisa Kit
  • complement component 1, s subcomponent (C1s) Elisa Kit
  • HtrA serine peptidase 1 (Htra1) Elisa Kit
  • HtrA serine peptidase 2 (HTRA2) Elisa Kit
  • melanoma antigen family B, 17-like (LOC783975) Elisa Kit
  • prothrombin-like (LOC100856539) Elisa Kit
  • serine protease (HTRA) Elisa Kit
  • THROMBIN protein (THROMBIN) Elisa Kit
  • AA959438 Elisa Kit
  • AI255193 Elisa Kit
  • AI327365 Elisa Kit
  • C1sa Elisa Kit
  • Cf-2 Elisa Kit
  • Cf2 Elisa Kit
  • F2 Elisa Kit
  • FII Elisa Kit
  • HTRA Elisa Kit
  • HTRA1 Elisa Kit
  • prothrombin Elisa Kit
  • PT Elisa Kit
  • RPRGL2 Elisa Kit
  • THPH1 Elisa Kit
  • thrombin Elisa Kit
  • wu:fb57c10 Elisa Kit
  • wu:fd42e09 Elisa Kit
  • wu:fd59d01 Elisa Kit
  • zgc:66319 Elisa Kit

Protein level used designations for F2

prothrombin , cell division cycle 34 homolog , serine protease , ubiquitin-conjugating enzyme Cdc34 , ubiquitin-conjugating enzyme E2 R1 , alpha-chymase , chymase , mast cell chymase , mast cell protease I , coagulation factor 2 , thrombin , prepro-coagulation factor II , prothrombin B-chain , C1 esterase , complement C1s-A subcomponent , complement component 1 subcomponent s-A , complement component C1SA

GENE ID SPECIES
325881 Danio rerio
712729 Macaca mulatta
299602 Rattus norvegicus
490628 Canis lupus familiaris
14061 Mus musculus
29251 Rattus norvegicus
2147 Homo sapiens
280685 Bos taurus
100144442 Sus scrofa
395306 Gallus gallus
100725988 Cavia porcellus
100307041 Ovis aries
50908 Mus musculus
100716225 Cavia porcellus
395990 Gallus gallus
783975 Bos taurus
100856539 Canis lupus familiaris
100008705 Oryctolagus cuniculus
100009146 Oryctolagus cuniculus
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