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Browse our anti-MGMT (MGMT) Antibodies

Full name:
anti-O6-Methylguanine-DNA-Methyltransferase Antibodies (MGMT)
On www.antibodies-online.com are 199 O6-Methylguanine-DNA-Methyltransferase (MGMT) Antibodies from 28 different suppliers available. Additionally we are shipping MGMT Kits (26) and MGMT Proteins (21) and many more products for this protein. A total of 258 MGMT products are currently listed.
Synonyms:
Agat, AGT, AI267024
list all antibodies Gene Name GeneID UniProt
MGMT 4255  
MGMT 17314 P26187
MGMT 25332 P24528

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Most Popular Reactivities for anti-MGMT (MGMT) Antibodies

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anti-Human MGMT Antibodies:

anti-Mouse (Murine) MGMT Antibodies:

anti-Rat (Rattus) MGMT Antibodies:

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Top referenced anti-MGMT Antibodies

  1. Human Monoclonal MGMT Primary Antibody for ICS, IP - ABIN967567 : Woodhead, Grist, Carlson, White, Waldstein, Cao: Presence of O6-methylguanine acceptor protein in the tissues of different classes of vertebrates and invertebrates. in Comparative biochemistry and physiology. B, Comparative biochemistry 1986 (PubMed)
    Show all 5 references for ABIN967567

  2. Human Monoclonal MGMT Primary Antibody for WB - ABIN1882265 : Tano, Shiota, Collier, Foote, Mitra: Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 5 references for ABIN1882265

  3. Human Monoclonal MGMT Primary Antibody for WB - ABIN1882266 : Rydberg, Spurr, Karran: cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells. in The Journal of biological chemistry 1990 (PubMed)
    Show all 5 references for ABIN1882266

  4. Human Monoclonal MGMT Primary Antibody for FACS, IHC (p) - ABIN180357 : Harris, Potter, Remack, Brent: A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells. in Cancer research 1992 (PubMed)
    Show all 4 references for ABIN180357

  5. Human Polyclonal MGMT Primary Antibody for EIA, WB - ABIN953415 : Svrcek, Buhard, Colas, Coulet, Dumont, Massaoudi, Lamri, Hamelin, Cosnes, Oliveira, Seruca, Gaub, Legrain, Collura, Lascols, Tiret, Fléjou, Duval: Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers. in Gut 2010 (PubMed)
    Show all 3 references for ABIN953415

  6. Human Polyclonal MGMT Primary Antibody for FACS, IHC (p) - ABIN391514 : Kim, Suh, Choi, Kang, Shin, Lee, Moon, Kim: Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations. in Human pathology 2009 (PubMed)
    Show all 3 references for ABIN391514

  7. Human Polyclonal MGMT Primary Antibody for IF (p), IHC (p) - ABIN730768 : Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

More Antibodies against MGMT Interaction Partners

Human O6-Methylguanine-DNA-Methyltransferase (MGMT) interaction partners

  1. Human O(6) -alkylguanine DNA alkyltransferase (hAGT) was capable of repairing both alkylene intrastrand cross-link containing duplexes with slightly greater efficiency towards the heptylene analog.

  2. MLH1 (show MLH1 Antibodies) and MGMT methylation correlated inversely when the tumor was located in the lower third of the stomach

  3. SFN (show SFN Antibodies) effectively inhibited activity of NF-kappaB (show NFKB1 Antibodies) signaling pathway and then reduced MGMT expression.

  4. review the current role of MGMT methylation and other epigenetic alterations as potential treatment targets in GI tumors

  5. The combined use of IDH1 (show IDH1 Antibodies) mutation and MGMT methylation status can be used as prognostic markers for long-term survival of patients with cerebral low-grade glioma.

  6. our studies prove a novel function of ERp29 (show ERP29 Antibodies)\MGMT in cancer cell survival against radiation. Targeting ERp29 (show ERP29 Antibodies)\MGMT axis may be useful for providing better treatment efficacy in combination with radiotherapy in breast cancer.

  7. Inhibition of DNA-repair genes Ercc1 (show ERCC1 Antibodies) and Mgmt enhances temozolomide efficacy in glioma treatment.

  8. Five-miRNA signature is an independent risk predictor for GBM with MGMT promoter methylation and can be used to identify patients at high risk of unfavorable outcome and resistant to alkylating chemotherapy.

  9. the presence of only the A allele at the rs34180180 single nucleotide polymorphism in malignant glioma was significantly associated with shorter overall survival, independently of the MGMT methylation status

  10. BO-1055 can be used for treating tumors that with deficient NER (show NR1H2 Antibodies), HR, and MGMT DNA repair genes.

Mouse (Murine) O6-Methylguanine-DNA-Methyltransferase (MGMT) interaction partners

  1. This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG (show C16orf35 Antibodies), as a key node in determining a carcinogenic threshold.

  2. Findings suggest that O6-methylguanine-DNA methyltransferase (MGMT)-mediated temozolomide resistance is associated with increased histone acetylation.

  3. Loss of MGMT expression and high Ezrin (show EZR Antibodies) protein expression leads to esophageal cancer.

  4. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.

  5. ta indicate that Zik1 and Gja9 (show GJD2 Antibodies) demonstrated cancer-specific aberrant DNA methylation (show HELLS Antibodies), whereas, Cdkn2a/p16 (show CDKN2A Antibodies), Igfbp3 (show IGFBP3 Antibodies), Mgmt, Id4 (show ID4 Antibodies), and Cxcr4 (show CXCR4 Antibodies) were methylated in both the AOM (show COL2A1 Antibodies) tumors and normal colon mucosa.

  6. Roles of MGMT and MLH1 (show MLH1 Antibodies) proteins in alkylation-induced apoptosis and mutagenesis.

  7. Repression of MGMT is associated with precancerous conditions in hyperplastic mucosa adjacent to colon cancer

  8. GAMT (show GAMT Antibodies) and AGAT (show GATM Antibodies) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (show DMD Antibodies) muscle compared to C57

  9. MGMT-deficient cells would likely exhibit an increased mutational burden, but only following exposures to specific environmental mutagens such as the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

  10. Mgmt suppresses intestinal cancer associated with exogenous alkylating agents.

MGMT Antigen Profile

Antigen Summary

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

Alternative names and synonyms associated with MGMT

  • O-6-methylguanine-DNA methyltransferase (MGMT) antibody
  • O-6-methylguanine-DNA methyltransferase (Mgmt) antibody
  • Agat antibody
  • AGT antibody
  • AI267024 antibody

Protein level used designations for MGMT

6-O-methylguanine-DNA methyltransferase , O-6-methylguanine-DNA-alkyltransferase , O6-methylguanine-DNA methyltransferase , methylated-DNA--protein-cysteine methyltransferase , methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , 0-6-methylguanine-DNA methyltransferase , O(6)-alkylguanine-DNA alkyltransferase , O6-alkylguanine-DNA alkyltransferase , O6-methylguanine-DNA methyltranferase , O6-alkylguanine-DNA-alkyltransferase , O6-methylguanine-DNA-methyltransferase

GENE ID SPECIES
4255 Homo sapiens
17314 Mus musculus
25332 Rattus norvegicus
100733185 Cavia porcellus
100155050 Sus scrofa
616091 Bos taurus
442978 Canis lupus familiaris
423965 Gallus gallus
101106897 Ovis aries
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