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Browse our anti-SLC6A3 (SLC6A3) Antibodies

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anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 Antibodies (SLC6A3)
On are 106 Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) Antibodies from 21 different suppliers available. Additionally we are shipping SLC6A3 Kits (45) and SLC6A3 Proteins (7) and many more products for this protein. A total of 165 SLC6A3 products are currently listed.
list all antibodies Gene Name GeneID UniProt
SLC6A3 13162 Q61327
SLC6A3 6531 Q01959
SLC6A3 24898 P23977

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anti-Mouse (Murine) SLC6A3 Antibodies:

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Top referenced anti-SLC6A3 Antibodies

  1. Mouse (Murine) Monoclonal SLC6A3 Primary Antibody for ICC, IF - ABIN1169684 : Cremona, Matthies, Pau, Bowton, Speed, Lute, Anderson, Sen, Robertson, Vaughan, Rothman, Galli, Javitch, Yamamoto: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. in Nature neuroscience 2011 (PubMed)
    Show all 3 references for ABIN1169684

  2. Human Polyclonal SLC6A3 Primary Antibody for FACS, IF (cc) - ABIN733373 : Ni, Hu, Ren, Luo, Li, Wan, Su: Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. in PLoS ONE 2013 (PubMed)
    Show all 3 references for ABIN733373

  3. Human Polyclonal SLC6A3 Primary Antibody for IHC (fro), WB - ABIN372614 : Kish, Kalasinsky, Derkach, Schmunk, Guttman, Ang, Adams, Furukawa, Haycock: Striatal dopaminergic and serotonergic markers in human heroin users. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001 (PubMed)

  4. Human Polyclonal SLC6A3 Primary Antibody for EIA, WB - ABIN954827 : Mazei-Robison, Bowton, Holy, Schmudermaier, Freissmuth, Sitte, Galli, Blakely: Anomalous dopamine release associated with a human dopamine transporter coding variant. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)

More Antibodies against SLC6A3 Interaction Partners

Rhesus Monkey Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. DNA of the impulsive but not the calm subjects was methylated at one DAT SNP.

  2. nitrative damage accumulates in midbrain neurons with age; The capacity of a dopamine neuron to accumulate more cytosolic DA, as inferred from DA transporter expression, is related to accumulation of nitrative damage

Caenorhabditis elegans (C. elegans) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. Endogenous dopamine actions in C. elegans are tightly regulated by synaptic DAT-1.

  2. loss of UNC-64/DAT-1 interactions leads to enhanced synaptic dopamine release

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. Data suggest that environment pollutants methylmercury and 1-methyl-4-phenylpyridinium decrease release of dopamine from dopaminergic neurons; this mechanism involves down-regulation of expression of Slc6a3.

  2. This study show that Dopamine transporter is enriched in filopodia and induces filopodia formation.

  3. The sigma-1R deficiency through suppressing NR2B (show GRIN2B Antibodies) function and DAT expression can reduce MPTP (show PTPN2 Antibodies)-induced death of dopaminergic neurons and parkinsonism.

  4. DAT gene knockout in mice results dendritic spine loss in pyramidal neurons in the CA1 (show CA1 Antibodies) field of the hippocampus.

  5. Results show that moderate increases in DAT function cause spontaneous dopaminergic cell loss, oxidative stress and fine motor impairment that is reversed by l-DOPA treatment

  6. Chronic and acute reductions of DAT functioning in mice impaired decision-making.

  7. These results demonstrate that the presence of the N-terminal tag leads to impaired DAT protein expression in vivo due in part to improper trafficking of the tagged transporter.

  8. studies demonstrate an in vivo functional impact of the DAT Val559 variant, providing support for the ability of DAT dysfunction to impact risk for mental illness.

  9. The data of this study imply that individual differences in DAT expression (either genetically or pharmacologically induced) may affect susceptibility to addiction of different types of psychostimulants.

  10. findings support the idea that altered DAT and VMAT2 (show Slc18a2 Antibodies) expression affect age-related changes in dopaminergic function.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. DAT-mediated dopamine uptake plays a role in the absorption and distribution of dopamine following intranasal administration

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. the dopamine transporter SLC6A3 constitutes a novel biomarker that is highly specific for clear cell renal cell carcinoma

  2. Data suggest that variants rs28363170 and rs3836790 in the solute carrier family 6 member 3 gene are not associated with sporadic Parkinson's disease in Han Chinese population.

  3. Study systematically designed and characterized a set of 24 substrate-based bivalent ligands, and in combination with mutagenesis, induced-fit docking calculations, electrophysiology, and cysteine accessibility measurements; revealed novel insight into the molecular basis of substrate recognition in hSERT (show SLC6A4 Antibodies) and hDAT

  4. these findings provide compelling experimental evidence that DAT N and C termini synergistically contribute to substrate and inhibitor affinities.

  5. these results are the first demonstration of pharmacological chaperoning of DAT and suggest this may be a viable approach to increase DAT levels in Dopamine Transporter Deficiency Syndrome and other conditions associated with reduced DAT function.

  6. total of 1799 differentially methylated regions were identified including SLC6A3, Rab40C, ZNF584, and FOXD3 whose significant methylation differences were confirmed in breast cancer patients through quantitative real-time polymerase chain reaction.Methylation of those aforementioned genes in white blood cells of our young patients may highlight their potential as early epimarkers

  7. Data indicate genetic association between dopamine transporter SLC6A3 (DAT1) and hypertension, and the specific variable number tandem repeats (VNTR) alleles of SLC6A3 may be a risk factor for hypertension.

  8. The effects of parenting on self-control and offending are most pronounced for those who carry plasticity alleles for both MAOA (show MAOA Antibodies) and DAT1. Thus, MAOA (show MAOA Antibodies) and DAT1 may be implicated in offending because they increase the negative effects of parenting on self-control. Implications for theory are discussed.

  9. The presence of particular variants of variable number tandem repeat polymorphisms in 3' untranslated region of SLC6A3 gene in men is associated with predisposition to certain forms of antisocial behavior.

  10. Increased nigral SLC6A3 activity may be a risk factor for SCZ.

SLC6A3 Antigen Profile

Antigen Summary

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.

Alternative names and synonyms associated with SLC6A3

  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (SLC6A3) antibody
  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (slc6a3) antibody
  • Protein DAT-1 (dat-1) antibody
  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (Slc6a3) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 3 (SLC6A3) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 3 (Slc6a3) antibody
  • DAT antibody
  • DAT1 antibody
  • PKDYS antibody
  • SLC6A3 antibody

Protein level used designations for SLC6A3

dopamine transporter variant II , sodium-dependent dopamine transporter , solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 , sodium-dependent dopamine transporter-like , DA transporter , dopamine transporter 1 , solute carrier family 6 member 3 , DAT , solute carrier family 6, member 3

574143 Macaca mulatta
609304 Canis lupus familiaris
750842 Pan troglodytes
100054747 Equus caballus
100393968 Callithrix jacchus
100478402 Ailuropoda melanoleuca
100488824 Xenopus (Silurana) tropicalis
176304 Caenorhabditis elegans
13162 Mus musculus
788410 Bos taurus
6531 Homo sapiens
24898 Rattus norvegicus
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