Browse our Epsin 1 Proteins (EPN1)

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Epsin 1 Proteins (EPN1)
On are 8 Epsin 1 (EPN1) Proteins from 6 different suppliers available. Additionally we are shipping Epsin 1 Antibodies (61) and many more products for this protein. A total of 75 Epsin 1 products are currently listed.
AA269831, fd51f09, Ibp1, MGC89328, wu:fd51f09, wu:fj90e03, zgc:56381
list all proteins Gene Name GeneID UniProt
EPN1 29924 Q9Y6I3
EPN1 13854 Q80VP1
EPN1 117277 O88339

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Epsin 1 Proteins (EPN1) by Origin

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More Proteins for Epsin 1 Interaction Partners

Human Epsin 1 (EPN1) interaction partners

  1. Data indicate that clathrin-mediated endocytosis of proto-oncogene (show RAB1A Proteins) protein erbB-3 (ErbB3 (show ERBB3 Proteins)) is depending on epsin-1.

  2. Epsins are required for Dishevelled (show DVL2 Proteins) stability and Wnt (show WNT2 Proteins) signalling activation in colon cancer development.

  3. AP-2 (show GTF3A Proteins) and epsin-1 are both required to promote efficient internalization of activated PAR1 (show MARK2 Proteins) and recognize discrete receptor sorting signals

  4. An epsin 1 helix is inserted into one leaflet of the lipid bilayer, inducing curvature; on lipid monolayers epsin alone is sufficient to facilitate the formation of clathrin-coated invaginations

  5. Together, these data provide evidence that CHIP functions to ubiquitylate the endocytic protein Epsin.

  6. epsin 1 promotes endocytosis of the ubiquitinated EGF receptor (show EGFR Proteins)

  7. Results show that epsin 1, an endocytic adapter protein (show TOLLIP Proteins), regulates mitotic membrane morphology and spindle integrity in HeLa cells.

Mouse (Murine) Epsin 1 (EPN1) interaction partners

  1. Epsins are required for Dishevelled (show DVL2 Proteins) stability and Wnt (show WNT2 Proteins) signalling activation in colon cancer development.

  2. epsins 1 and 2 have a critical role in the temporal and spatial regulation of VEGFR3 (show FLT4 Proteins) abundance and signaling in collecting lymphatic trunks during lymphatic valve formation

  3. Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.

  4. Epsins function specifically to downregulate VEGFR2 by mediating activated VEGFR2 internalization and degradation and that genetic reduction of VEGFR2 level protects against excessive angiogenesis caused by epsin loss.

  5. Data indicate a Cbl (show CBL Proteins)/p85 (show ECM1 Proteins)/epsin-1 pathway in erythropoietin receptor (EpoR (show EPOR Proteins)) endocytosis.

  6. Loss of epsins 1 and 2 impaired endocytosis and degradation of VEGFR2, resulting in excessive VEGF signaling and compromised tumor vascular function.

  7. epsin is an accessory protein linking ENaC to the clathrin-based endocytic machinery thereby regulating the activity of this ion channel at the cell surface

  8. epsin has a role as a specialized endocytic adaptor, with a critical role in the activation of Notch (show NOTCH1 Proteins) signaling in mammals

Epsin 1 (EPN1) Protein Profile

Protein Summary

The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Epsin 1 (EPN1)

  • epsin 1 (epn1)
  • epsin 1 (EPN1)
  • epsin 1 (Epn1)
  • Epsin 1 (Epn1)
  • epsin-1-like (EPN1)
  • AA269831 protein
  • fd51f09 protein
  • Ibp1 protein
  • MGC89328 protein
  • wu:fd51f09 protein
  • wu:fj90e03 protein
  • zgc:56381 protein

Protein level used designations for Epsin 1 Proteins (EPN1)

epsin 1 , epsin-1 , Epsin-1 , epsin-1-like , EH domain-binding mitotic phosphoprotein , EPS-15-interacting protein 1 , intersectin-EH-binding protein 1

406671 Danio rerio
448609 Xenopus (Silurana) tropicalis
508199 Bos taurus
702956 Macaca mulatta
100050807 Equus caballus
100380412 Salmo salar
100458513 Pongo abelii
100475259 Ailuropoda melanoleuca
100605504 Nomascus leucogenys
29924 Homo sapiens
608964 Canis lupus familiaris
13854 Mus musculus
117277 Rattus norvegicus
782204 Bos taurus
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