Browse our RAB7A, Member RAS Oncogene Family Proteins (RAB7A)

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RAB7A, Member RAS Oncogene Family Proteins (RAB7A)
On www.antibodies-online.com are 14 RAB7A, Member RAS Oncogene Family (RAB7A) Proteins from 7 different suppliers available. Additionally we are shipping RAB7A, Member RAS Oncogene Family Antibodies (48) and RAB7A, Member RAS Oncogene Family Kits (1) and many more products for this protein. A total of 66 RAB7A, Member RAS Oncogene Family products are currently listed.
Synonyms:
ARABIDOPSIS RAB GTPASE HOMOLOG G2, ATRAB7A, ATRABG2, DDBDRAFT_0190210, DDBDRAFT_0191507, DDB_0190210, DDB_0191507, F7D8.20, F7D8_20, LOC100231734, PRO2706, rab-7, Rab7, Rab7a, RAB GTPase homolog 7A, zgc:64058
list all proteins Gene Name GeneID UniProt
RAB7A 19349 P51150
RAB7A 7879 P51149
RAB7A 29448 P09527

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RAB7A, Member RAS Oncogene Family Proteins (RAB7A) by Origin

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Top referenced RAB7A, Member RAS Oncogene Family Proteins

  1. Human RAB7A Protein expressed in Escherichia coli (E. coli) - ABIN667328 : Feng, Press, Wandinger-Ness: Rab 7: an important regulator of late endocytic membrane traffic. in The Journal of cell biology 1996 (PubMed)
    Show all 2 references for 667328

  2. Human RAB7A Protein expressed in HEK-293 Cells - ABIN2730367 : Ye, Gao, Tian, Yearsley, Lange, Robertson, Barsky: Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7. in Molecular cancer research : MCR 2012 (PubMed)

More Proteins for RAB7A, Member RAS Oncogene Family Interaction Partners

Arabidopsis thaliana RAB7A, Member RAS Oncogene Family (RAB7A) interaction partners

  1. MON1/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-mediated Rab7 activation was indispensable for vacuolar trafficking of tapetum degradation-related cysteine proteases.

Zebrafish RAB7A, Member RAS Oncogene Family (RAB7A) interaction partners

  1. Data provide new insight into how disease-associated alterations in Rab7 protein disrupt cellular function in vertebrate sensory neurons. Moreover, findings suggest that defects in axon development may be a previously unrecognized component of Charcot-Marie-Tooth2b disease.

  2. The established transgenic lines ubiquitously express EGFP fusions of Rab5c (show Rab5c Proteins) (early endosomes), Rab11a (show RAB11A Proteins) (recycling endosomes), and Rab7 (late endosomes) to study localization and dynamics during development.

Mouse (Murine) RAB7A, Member RAS Oncogene Family (RAB7A) interaction partners

  1. WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway.

  2. Vps34 (show PIK3C3 Proteins) has a previously unknown role in regulating Rab7 activity and late endosomal trafficking.

  3. Rab7 accumulated in GCase (show GBA Proteins) deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase (show GBA Proteins) can reverse ALR (show GFER Proteins) impairment, we anticipate that strategies to restore GCase (show GBA Proteins) activity in the brains of both sporadic patients with PD and those with GBA1 (show GBA Proteins) mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  4. The up-regulation of Rab11 (show RAB11A Proteins), Rab7, or RILP (show RILP Proteins), but not its truncated form RILP (show RILP Proteins)-C33 (show CD82 Proteins), rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 (show RAB11A Proteins) or Rab7 impaired LAMP2A trafficking.

  5. The inhibition of autophagosome-lysosome fusion induced by SapM is dependent on the interaction between SapM and Rab7.

  6. Prion (show PRNP Proteins) infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cells.

  7. photoreceptor outer segments vesicles engulfed through Lyar-dependent pathway were targeted to phagosomes and colocalized with phagosome marker Rab7

  8. B cell Rab7 mediates induction of activation-induced cytidine deaminase (show AICDA Proteins) expression and class-switching in T-dependent and T-independent antibody responses.

  9. CREG1 (show CREG1 Proteins) deficiency influenced the maturation of lysosomes and reduced the espression of Rab7, which might be involved in CREG1 (show CREG1 Proteins)-induced cardiomyocyte autophagy.

  10. Tropheryma whipplei blocks the switch from Rab5 (show RAB5A Proteins) to Rab7.

Human RAB7A, Member RAS Oncogene Family (RAB7A) interaction partners

  1. WDR91 serves as a Rab7 (show RAB7B Proteins) effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway.

  2. The Vici syndrome protein EPG5 is a Rab7 (show RAB7B Proteins) effector that determines the fusion specificity of autophagosomes with late endosomes/lysosomes.

  3. up-regulation of RAB7A reported in Alzheimer's disease, could contribute to the extracellular accumulation of pathological TAU

  4. Rab7 (show RAB7B Proteins) accumulated in GCase (show GBA Proteins) deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase (show GBA Proteins) can reverse ALR (show GFER Proteins) impairment, we anticipate that strategies to restore GCase (show GBA Proteins) activity in the brains of both sporadic patients with PD and those with GBA1 (show GBA Proteins) mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  5. Rab7a depletion decreases the amount of active Rac1 but not its abundance and reduces the number of cells with vimentin (show VIM Proteins) filaments facing the wound, indicating that Rab7a has a role in the orientation of vimentin (show VIM Proteins) filaments during migration

  6. The study highlighted the importance of a phosphorylation/dephosphorylation switch in controlling timely Rab7 (show RAB7B Proteins) localization and activity on endosomes.

  7. show that the maturation of Mtb (show NCAPG2 Proteins)-containing autophagosomes into autolysosomes required recruitment of the late endosome marker RAB7 (show RAB7B Proteins), forming the intermediate compartment amphisomes

  8. We validated ANKRD13A as a novel constituent of BCR (show BCR Proteins) signalosome and showed that BCR (show BCR Proteins)-induced phosphorylation of RAB7A at S72 regulates its association with its effector proteins and with endo-lysosomal compartments.

  9. Hepatitis B virus can regulate its own secretion through an activation of the endo-lysosomal and autophagic pathway mediated by Rab7 (show RAB7B Proteins) activation.

  10. provides molecular insights into the essential role of Vps26 (show VPS26A Proteins) and Vps35 (show vps35 Proteins) in Rab7 (show RAB7B Proteins)-mediated recruitment of the core retromer complex

RAB7A, Member RAS Oncogene Family (RAB7A) Protein Profile

Protein Summary

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Alternative names and synonyms associated with RAB7A, Member RAS Oncogene Family (RAB7A)

  • RAB7A, member RAS oncogene family (RAB7A)
  • RAB7A, member RAS oncogene family (rab7a)
  • RAB7A, member RAS oncogene family (LOC100231734)
  • rab7A protein (rab7A)
  • RAB GTPase-like protein 7A (RAB7A)
  • Rab GTPase (rab7A)
  • ras-related protein rab-7a (rab7a)
  • dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1)
  • RAB7, member RAS oncogene family (rab7)
  • RAB7, member RAS oncogene family (Rab7)
  • RAB7A, member RAS oncogene family (Rab7a)
  • ARABIDOPSIS RAB GTPASE HOMOLOG G2 protein
  • ATRAB7A protein
  • ATRABG2 protein
  • DDBDRAFT_0190210 protein
  • DDBDRAFT_0191507 protein
  • DDB_0190210 protein
  • DDB_0191507 protein
  • F7D8.20 protein
  • F7D8_20 protein
  • LOC100231734 protein
  • PRO2706 protein
  • rab-7 protein
  • Rab7 protein
  • Rab7a protein
  • RAB GTPase homolog 7A protein
  • zgc:64058 protein

Protein level used designations for RAB7A

ras-related protein Rab-7 , ras-related protein Rab-7a , RAB7A, member RAS oncogene family , rab7A protein , ras-related protein rab-7a , RAB7, member RAS oncogene family , dystroglycan , dystrophin-associated glycoprotein 1 , Ras-associated protein RAB7 , GTP-binding protein (rab7) , ras-related protein BRL-RAS , ras-related protein p23

GENE ID SPECIES
470919 Pan troglodytes
493388 Xenopus (Silurana) tropicalis
707280 Macaca mulatta
100145880 Ovis aries
100231734 Taeniopygia guttata
553895 Lotus japonicus
816724 Arabidopsis thaliana
8616852 Dictyostelium discoideum AX4
100528204 Ictalurus punctatus
281439 Bos taurus
393902 Danio rerio
19349 Mus musculus
7879 Homo sapiens
398880 Xenopus laevis
416016 Gallus gallus
404007 Canis lupus familiaris
29448 Rattus norvegicus
509970 Bos taurus
100008682 Oryctolagus cuniculus
100174486 Pongo abelii
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