RAB7A Products
(RAB7A, Member RAS Oncogene Family (RAB7A))
Categories
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008].
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Featured RAB7A Categories
RAB7A Antibodies
High quality antibodies with extensive validation data.
RAB7A ELISA Kits
Reliable ELISA kits for a wide range of species.
RAB7A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAB7A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), FACS
Validations
- (7)
Cat. No.
ABIN652609
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN6254195
Quantity
600 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc)
Validations
- (1)
- (3)
Cat. No.
ABIN720191
Quantity
100 μL
Datasheet
Datasheet
Recommended RAB7A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959032
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951224
Quantity
96 tests
Datasheet
Datasheet
Recommended RAB7A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124764
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317193
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7321067
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RAB7A products
: "Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9." in: Nature communications, Vol. 8, pp. 15363, (2018) (PubMed).: "Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease." in: The EMBO journal, Vol. 36, Issue 22, pp. 3356-3371, (2017) (PubMed).
: "Rab7 Regulates CDH1 Endocytosis, Circular Dorsal Ruffles Genesis, and Thyroglobulin Internalization in a Thyroid Cell Line." in: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1695-708, (2016) (PubMed).
: "Intracellular pathways following uptake of bevacizumab in RPE cells." in: Experimental eye research, Vol. 131, pp. 29-41, (2015) (PubMed).
: "Large putative PEST-like sequence motif at the carboxyl tail of human calcium receptor directs lysosomal degradation and regulates cell surface receptor level." in: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 4165-76, (2012) (PubMed).
: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).
: "Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules." in: Journal of virology, Vol. 86, Issue 24, pp. 13653-61, (2012) (PubMed).
: "Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene." in: Neurology, Vol. 67, Issue 8, pp. 1476-8, (2006) (PubMed).
: "Structural basis for recruitment of RILP by small GTPase Rab7." in: The EMBO journal, Vol. 24, Issue 8, pp. 1491-501, (2005) (PubMed).
: "Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy." in: American journal of human genetics, Vol. 72, Issue 3, pp. 722-7, (2003) (PubMed).
Synonyms and alternative names related to RAB7A
RAB5A, member RAS oncogene family (RAB5A), RAB7A, member RAS oncogene family (RAB7A), RAB7A, member RAS oncogene family (Rab7a), RAB7A, member RAS oncogene family L homeolog (rab7a.L), RAB7A, member RAS oncogene family (rab7a), rab7A protein (rab7A), RAB GTPase homolog 7A (RAB7A), Rab GTPase (rab7A), ras-related protein rab-7a (rab7a), RAB7, member RAS oncogene family (Rab7), RAB7, member RAS oncogene family (rab7), ARABIDOPSIS RAB GTPASE HOMOLOG G2, ATRAB7A, ATRABG2, DDBDRAFT_0190210, DDBDRAFT_0191507, DDB_0190210, DDB_0191507, F7D8.20, F7D8_20, LOC100231734, PRO2706, pro2706, rab-7, RAB5, RAB7, Rab7, rab7, RAB7A, Rab7a, RAB GTPase homolog 7A, zgc:64058Protein level used designations for RAB7A
- RAS-associated protein RAB5A
- ras-related protein Rab-5A
- RAB7, member RAS oncogene family
- Ras-associated protein RAB7
- ras-related protein Rab-7a
- ras-related protein BRL-RAS
- ras-related protein p23
- GTP-binding protein (rab7)
- ras-related protein Rab-7
- RAB7A, member RAS oncogene family
- rab7A protein
- ras-related protein rab-7a
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