Browse our anti-RICTOR (RICTOR) Antibodies

Full name:
anti-RPTOR Independent Companion of MTOR, Complex 2 Antibodies (RICTOR)
On are 188 RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) Antibodies from 21 different suppliers available. Additionally we are shipping RICTOR Kits (3) and and many more products for this protein. A total of 202 RICTOR products are currently listed.
4921505C17Rik, 6030405M08Rik, AVO3, AW492497, D530039E11Rik, Fyb, mAVO3, PIA
list all antibodies Gene Name GeneID UniProt
RICTOR 253260 Q6R327
RICTOR 78757 Q6QI06
RICTOR 310131  

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anti-Human RICTOR Antibodies:

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anti-Rat (Rattus) RICTOR Antibodies:

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Top referenced anti-RICTOR Antibodies

  1. Human Polyclonal RICTOR Primary Antibody for IP, WB - ABIN152042 : Hresko, Mueckler: mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. in The Journal of biological chemistry 2005 (PubMed)
    Show all 33 references for 152042

  2. Human Polyclonal RICTOR Primary Antibody for FACS, ICC - ABIN152043 : Jindra, Jin, Rozengurt, Reed: HLA class I antibody-mediated endothelial cell proliferation via the mTOR pathway. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 17 references for 152043

  3. Human Polyclonal RICTOR Primary Antibody for EIA, IHC (p) - ABIN359477 : Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. in Cell 2006 (PubMed)
    Show all 4 references for 359477

  4. Human Polyclonal RICTOR Primary Antibody for EIA, IHC (p) - ABIN359480 : Pearce, Huang, Boudeau, Paw?owski, Wullschleger, Deak, Ibrahim, Gourlay, Magnuson, Alessi: Identification of Protor as a novel Rictor-binding component of mTOR complex-2. in The Biochemical journal 2007 (PubMed)
    Show all 3 references for 359480

  5. Human Monoclonal RICTOR Primary Antibody for ELISA, FACS - ABIN4350528 : Loganathan, Kandala, Gupta, Srivastava: Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. in PLoS ONE 2012 (PubMed)
    Show all 2 references for 4350528

  6. Human Polyclonal RICTOR Primary Antibody for IHC, ELISA - ABIN185390 : Sarbassov, Ali, Kim, Guertin, Latek, Erdjument-Bromage, Tempst, Sabatini: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. in Current biology : CB 2004 (PubMed)
    Show all 2 references for 185390

  7. Human Polyclonal RICTOR Primary Antibody for IHC (p), WB - ABIN391384 : Gao, Wu, Spencer, Johnson, Bazer et al.: Select nutrients in the ovine uterine lumen. VI. Expression of FK506-binding protein 12-rapamycin complex-associated protein 1 (FRAP1) and regulators and effectors of mTORC1 and mTORC2 complexes in ... in Biology of reproduction 2009 (PubMed)
    Show all 2 references for 391384

  8. Human Monoclonal RICTOR Primary Antibody for ICC, FACS - ABIN969382 : Yang, Inoki, Ikenoue, Guan: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. in Genes & development 2006 (PubMed)

More Antibodies against RICTOR Interaction Partners

Human RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. miR (show MLXIP Antibodies)-153 downregulation could be one important reason of Rictor upregulation and mTORC2 (show CRTC2 Antibodies) over-activation in glioma cells. Further, miR (show MLXIP Antibodies)-153-induced anti-glioma cell activity is possibly via downregulating Rictor.

  2. These results point to an increase in total and phosphorylated Akt (show AKT1 Antibodies) in high-grade gliomas and to a possible role of RICTOR in proliferations of high-grade glioblastomas cells.

  3. Hgh mTOR (show FRAP1 Antibodies) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor (show RPTOR Antibodies) expression evaluation revealed even stronger statistical correlation with prognosis.

  4. In this study we began by validating the expression of four main mTOR (show FRAP1 Antibodies) pathway components, mTOR (show FRAP1 Antibodies), DEPTOR (show DEPTOR Antibodies), rictor and raptor (show RPTOR Antibodies), at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  5. Based on univariate and multivariate Cox (show COX8A Antibodies) proportional hazards regression analysis, RICTOR-positive expression, AJCC staging III or IV and nodal metastasis are prognostic factors and the former two are independent risk factors for esophageal squamous cell carcinoma.

  6. Taken together, our results suggest that the proinflammatory cytokine TNFalpha (show TNF Antibodies) promotes the expression of Rictor through the NF-kappaB (show NFKB1 Antibodies) pathway in renal cell carcinoma (show MOK Antibodies).

  7. RICTOR amplification may define a novel and unique molecular subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors.

  8. Data show that rapamycin-insensitive companion of mTOR protein (RICTOR) plays a central role in phosphatidylinositol 3-kinase (PI3K (show PIK3CA Antibodies))/proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-akt (AKT (show AKT1 Antibodies)) pathway in melanocytes and its deregulation could be involved in melanoma development.

  9. Mdm20 (show NAA25 Antibodies) acts as a novel regulator of Rictor, thereby controlling mTORC2 (show CRTC2 Antibodies) activity, and leading to the activation of PKCalphaS657 and FoxO1 (show FOXO1 Antibodies).

  10. RICTOR/MTORC2 (show CRTC2 Antibodies)-AKT (show AKT1 Antibodies) can integrate convergent hormonal and metabolic signals to provide coordinated and sensitive regulation of hepatic FOXO1 (show FOXO1 Antibodies)-target gene expression.

Mouse (Murine) RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. These findings reveal a novel functional pathway important for age-related bone loss and support for miR (show MLXIP Antibodies)-218 and Rictor as potential targets for therapeutic intervention for age-related osteoporosis treatment.

  2. this study shows that Rictor is required for NKT (show CTSL1 Antibodies)-17 cell development and normal iNKT-cell cytolytic function

  3. data suggest that Rictor/mTORC2 (show CRTC2 Antibodies) controls an amino acid-sensitive checkpoint that allows T cells to determine whether the microenvironment contains sufficient resources for daughter cell generation.

  4. Loss of DNMT3B (show DNMT3B Antibodies) results in hypomethylation of the miR (show MLXIP Antibodies)-196b promoter and increased miR (show MLXIP Antibodies)-196b expression, which directly targets the mTORC2 (show CRTC2 Antibodies) component Rictor.

  5. Rictor in the limb mesenchymal lineage is required for the normal response to the anti-sclerostin (show SOST Antibodies) therapy in both bone formation and resorption.

  6. Low RICTOR expression was detected in quiescent, confluent mouse aortic endothelial cells, whereas high doses of FGF2 (show FGF2 Antibodies) induced high RICTOR expression that was associated with strong mTORC2 (show CRTC2 Antibodies)-specific protein kinase (show CDK7 Antibodies) Ca and AKT (show AKT1 Antibodies) phosphorylation

  7. analysis of mTORC2 (show CRTC2 Antibodies) components mTOR (show FRAP1 Antibodies), Rictor and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  8. Adipose tissue mTORC2 (show CRTC2 Antibodies) regulates via Rictor ChREBP (show MLXIPL Antibodies)-driven de novo lipogenesis and hepatic glucose metabolism.

  9. Rictor is essential for the generation of type II IFN-dependent antiviral and antiproliferative responses and that it controls the generation of type II IFN-suppressive effects on normal and malignant hematopoiesis

  10. Study suggests that Rictor/mTORC2 (show CRTC2 Antibodies) signaling activation mediates TGFbeta1 (show TGFB1 Antibodies)-induced fibroblast activation and contributes to the development of kidney fibrosis.

RICTOR Antigen Profile

Antigen Summary

RICTOR and MTOR (FRAP1\; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004

Alternative names and synonyms associated with RICTOR

  • RPTOR independent companion of MTOR, complex 2 (RICTOR) antibody
  • rapamycin-insensitive companion of mTOR (LOC100357138) antibody
  • RPTOR independent companion of MTOR, complex 2 (Rictor) antibody
  • 4921505C17Rik antibody
  • 6030405M08Rik antibody
  • AVO3 antibody
  • AW492497 antibody
  • D530039E11Rik antibody
  • Fyb antibody
  • mAVO3 antibody
  • PIA antibody

Protein level used designations for RICTOR

rapamycin-insensitive companion of mTOR , AVO3 homolog , TORC2-specific protein AVO3 , hAVO3 , pianissimo , mAVO3 , protein pianissimo , FYN binding protein , rapamycin insensitive companion of mTOR

694915 Macaca mulatta
100357138 Oryctolagus cuniculus
253260 Homo sapiens
78757 Mus musculus
479356 Canis lupus familiaris
310131 Rattus norvegicus
527459 Bos taurus
100519575 Sus scrofa
100715888 Cavia porcellus
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