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Browse our anti-VAV2 (VAV2) Antibodies

Full name:
anti-Vav 2 Guanine Nucleotide Exchange Factor Antibodies (VAV2)
On are 59 Vav 2 Guanine Nucleotide Exchange Factor (VAV2) Antibodies from 14 different suppliers available. Additionally we are shipping VAV2 Kits (5) and and many more products for this protein. A total of 74 VAV2 products are currently listed.
2810040F13Rik, AI847175, VAV-2
list all antibodies Gene Name GeneID UniProt
VAV2 7410 P52735
VAV2 296603  
VAV2 22325 Q60992

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Most Popular Reactivities for anti-VAV2 (VAV2) Antibodies

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anti-Human VAV2 Antibodies:

anti-Rat (Rattus) VAV2 Antibodies:

anti-Mouse (Murine) VAV2 Antibodies:

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Top referenced anti-VAV2 Antibodies

  1. Dog (Canine) Polyclonal VAV2 Primary Antibody for EIA, WB - ABIN782902 : Henske, Short, Jozwiak, Bovey, Ramlakhan, Haines, Kwiatkowski: Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1. in Annals of human genetics 1995 (PubMed)

More Antibodies against VAV2 Interaction Partners

Human Vav 2 Guanine Nucleotide Exchange Factor (VAV2) interaction partners

  1. The crystal structure of the complex between a phosphorylated PPxY motif of TXNIP (show TXNIP Antibodies) and the SH2 domain of Vav2 reveals a conserved recognition mechanism.

  2. Our data provide the first evidence to implicate VAV2 in glucose-induced Rac1 activation, actin remodelling and glucose-stimulated insulin (show INS Antibodies) secretion in pancreatic beta cells.

  3. VAV2 is required for Met signaling in the perinuclear endosome.

  4. Authors propose a model whereby vimentin (show VIM Antibodies) promotes FAK (show PTK2 Antibodies) stabilization through VAV2-mediated Rac1 activation. This model may explain why vimentin (show VIM Antibodies) expressing metastatic lung cancer cells are more motile and invasive.

  5. Data suggest a coordination between paxillin (show PXN Antibodies) kinase linker (PKL (show PKLR Antibodies))/Vav2 signaling and PKL (show PKLR Antibodies)/beta-PIX (show ARHGEF7 Antibodies) signaling during cell migration.

  6. the guanine nucleotide exchange factor (show RASGRF1 Antibodies) (GEF (show SLC2A4RG Antibodies)) Vav2 is identified as a candidate partner for KCC3 (show SLC12A6 Antibodies).

  7. Two variants of VAV2 and VAV3 (show VAV3 Antibodies), rs2156323 and rs2801219, respectively, were identified in Japanese patients with primary open angle glaucoma, normal tension glaucoma, and developmental glaucoma.

  8. Upregulation of Rac1 activity by Wnt3a (show WNT3A Antibodies) temporally correlated with enhanced p120-catenin (show CTNND1 Antibodies) binding to Rac1 and Vav2.

  9. Studies indicate relevance of P-Rex1 (show PREX1 Antibodies) and P-Rex2a, in breast tumorigenesis, and suggest that the exchange factors Vav2 and Vav3 (show VAV3 Antibodies) play synergistic roles in breast cancer by sustaining tumor growth, neoangiogenesis, and metastasis.

  10. Data indicate that Vav2 and Vav3 (show VAV3 Antibodies) controlled a vast transcriptional program in breast cancer cells through mechanisms that were shared between the two proteins, isoform-specific or synergistic.

Mouse (Murine) Vav 2 Guanine Nucleotide Exchange Factor (VAV2) interaction partners

  1. Results show that Vav2 and Rac1 are commonly involved in blood pressure regulation.

  2. Data demonstrate that the co-expression of the exchange factors Vav2 and Vav3 (show VAV3 Antibodies) is critical for the development of this tumor type.

  3. Vav2 and Vav3 (show VAV3 Antibodies) are required for normal peripheral nerve degeneration/regeneration, revascularization and functional recovery.

  4. The results indicate that ADIP (show SSX2IP Antibodies) plays an essential role in PDGF (show PDGFA Antibodies)-induced cell movement by interacting with afadin (show MLLT4 Antibodies) and Vav2 and regulating the activation of Rac (show AKT1 Antibodies).

  5. CD36 (show CD36 Antibodies) contributes to activation of Vav-1 (show VAV1 Antibodies), -2, and -3 in aortae from hyperlipidemic mice

  6. Cbl (show CBL Antibodies) ubiquitin ligase (show RNF123 Antibodies) plays a critical role in the maintenance of AJs and suppression of cell migration through down-regulation of EGFR (show EGFR Antibodies)-Vav2 signaling.

  7. Data show that Vav2/Vav3 (show VAV3 Antibodies)-deficient mice show early onset of iridocorneal angle changes and elevated intraocular pressure, with subsequent selective loss of retinal ganglion cells and optic nerve head cupping, which are the hallmarks of glaucoma.

  8. Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.

  9. does not contribute to platelet aggregation by CRP (show CRP Antibodies) and thrombin (show F2 Antibodies), and is not required for regulation of phospholipase C (show PLC Antibodies).

  10. Vav2 and Tiam1 (show TIAM1 Antibodies) may act as downstream effectors of Src (show SRC Antibodies), thereby regulating Rac1-dependent pathways that participate in Src (show SRC Antibodies)-induced cell transformation

VAV2 Antigen Profile

Antigen Summary

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with VAV2

  • vav 2 guanine nucleotide exchange factor (VAV2) antibody
  • vav 2 guanine nucleotide exchange factor (Vav2) antibody
  • vav 2 oncogene (Vav2) antibody
  • 2810040F13Rik antibody
  • AI847175 antibody
  • VAV-2 antibody

Protein level used designations for VAV2

guanine nucleotide exchange factor VAV2 , vav 2 oncogene , Vav2 oncogene , VAV-2

7410 Homo sapiens
608060 Canis lupus familiaris
296603 Rattus norvegicus
100151931 Sus scrofa
515718 Bos taurus
22325 Mus musculus
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