Browse our AGRP Proteins (AGRP)

Full name:
Agouti Related Protein Homolog (Mouse) Proteins (AGRP)
On are 33 Agouti Related Protein Homolog (Mouse) (AGRP) Proteins from 10 different suppliers available. Additionally we are shipping AGRP Antibodies (96) and AGRP Kits (62) and many more products for this protein. A total of 217 AGRP products are currently listed.
list all proteins Gene Name GeneID UniProt
AGRP 11604 P56473
AGRP 181 O00253
AGRP 25582  

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AGRP Proteins (AGRP) by Origin

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Top referenced AGRP Proteins

  1. Human AGRP Protein expressed in Human Cells - ABIN2002011 : Ollmann, Wilson, Yang, Kerns, Chen, Gantz, Barsh: Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 5 references for 2002011

  2. Mouse (Murine) AGRP Protein expressed in Human Cells - ABIN2007600 : Yang, Chen, Lai, Gantz, Yagmurlu, Georgeson, Harmon: Molecular determination of agouti-related protein binding to human melanocortin-4 receptor. in Molecular pharmacology 2003 (PubMed)
    Show all 5 references for 2007600

  3. Rhesus Monkey AGRP Protein expressed in Human Cells - ABIN2009970 : Breit, Wolff, Kalwa, Jarry, Büch, Gudermann: The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors. in The Journal of biological chemistry 2006 (PubMed)
    Show all 5 references for 2009970

  4. Human AGRP Protein expressed in Escherichia coli (E. coli) - ABIN1046484 : Shutter, Graham, Kinsey, Scully, Lüthy, Stark: Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. in Genes & development 1997 (PubMed)
    Show all 3 references for 1046484

More Proteins for AGRP Interaction Partners

Mouse (Murine) Agouti Related Protein Homolog (Mouse) (AGRP) interaction partners

  1. These findings indicate that the relevance of AgRP to POMC (show POMC Proteins) neuron GABA connectivity depends on the state of AgRP neuron activity and suggest that different types of transmitter release should be considered when circuit mapping.

  2. CRFR1 (show CRHR1 Proteins), in a subset of AgRP neurons, plays a regulatory role that enables appropriate sympathetic nervous system activation and consequently protects the organism from hypothermia and hypoglycemia.

  3. Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY (show NPY Proteins) neurons in mice.

  4. Data show that agouti-related protein (AgRP)-glucocorticoid receptor (show NR3C1 Proteins) knockout (GR-/-) mice are resistant to diet-induced obesity.

  5. Data show that chronic caloric restriction (CR) alters hypothalamic agouti-related protein (Agrp) and neuropeptide Y (Npy (show NPY Proteins)) gene expression similarly in Ghrelin (show GHRL Proteins)+/+, Ghrelin (show GHRL Proteins)-/-, ghrelin receptor Ghsr (show GHSR Proteins)+/+, and Ghsr (show GHSR Proteins)-/- mice.

  6. Suppression of sympathetic tone in AgRP-Sirt1 (show SIRT1 Proteins)/(--) mice reversed osteopenia in transgenic animals.

  7. Data (including data from studies in transgenic/knockout mice) suggest that expression in adult brain neurons (especially in parabrachial nucleus) of both Dmbx1 (show DMBX1 Proteins) (deleted in malignant brain tumors 1 (show DMBT1 Proteins)) and AgRP is important in appetite regulation.

  8. mTORC1 in Agrp neurons controls circadian expression of orexigenic neuropeptides but is dispensable for the regulation of feeding behavior and energy metabolism

  9. Absence of Mc3rs (but not Ghsrs) was associated with lower AgRP/Npy (show NPY Proteins) expression, suggesting attenuated responses to signals of negative energy balance.

  10. These experiments reveal both overlapping and nonredundant effects of JNK (show MAPK8 Proteins)- and IKK (show CHUK Proteins)-dependent signaling in AgRP neurons.

Human Agouti Related Protein Homolog (Mouse) (AGRP) interaction partners

  1. data provide compelling evidence that AgRP is a heparan sulfate-binding protein and localizes critical regions in the AgRP structure required for this interaction.

  2. The aim of this survey is to evaluate the association of genetic variants of melanocortin-4-receptor (MC4R (show MC4R Proteins)), pro-opiomelanocortin (POMC (show POMC Proteins)), apolipoprotein E (APOE (show APOE Proteins)) and agouti-related protein (AGRP) with obesity in the North Indian population.

  3. CSF (show CSF2 Proteins) AgRP was not different in lean vs. overweight/obese subjects; however, plasma AgRP was higher in lean subjects.

  4. human agouti-related protein has a role in enhancing expression and stability of human melanocortin-4 receptor (show MC4R Proteins)

  5. Variations in genes AGRP, CPE (show CPE Proteins), GHRL (show GHRL Proteins), GLP1R (show GLP1R Proteins), HTR2A, NPY1R (show NPY1R Proteins), NPY5R (show NPY5R Proteins), SOCS3 (show SOCS3 Proteins) and STAT3 (show STAT3 Proteins) showed modest associations with BMI in European Americans.

  6. Elevations in AgRP also favor the diagnosis of ectopic ACTH (show POMC Proteins) syndrome, suggesting AgRP should be further evaluated as a potential neuroendocrine tumor marker.

  7. AGRP SNP (rs1338993) was not associated with antipsychotic-induced weight gain in schizophrenia patients.

  8. Data suggest that prolonged steady-state exercise/physical activity at moderate intensity elicits substantial increases in blood lactate and cortisol concentrations without a significant change in AgRP; study was pilot project involving men.

  9. Despite peripheral hyperleptinemia, positive energy balance is achieved during pregnancy by a relative decrease in central leptin (show LEP Proteins) concentrations and resistance to leptin's effects on target neuropeptides that regulate energy balance.

  10. AgRP and NPY (show NPY Proteins) are correlated with body weight changes, rather than the presence of type 2 diabetes, whereas changes in alphaMSH (show POMC Proteins) immunoreactivity are related to the presence of type 2 diabetes, indicating separate hypothalamic mechanisms.

Cow (Bovine) Agouti Related Protein Homolog (Mouse) (AGRP) interaction partners

  1. (Nle4, d-Phe7)-alphaMSH (show POMC Proteins) (NDP (show NDP Proteins)-alphaMSH (show POMC Proteins)) stimulated the production of cortisol and these effects were abolished by agouti related protein or SHU9119, a synthetic antagonist of melanocortin 3 and melanocortin 4 receptor (show MC4R Proteins)

  2. Agrp inhibited, in a dose-dependent manner, the 10(-9) M NDP (show NDP Proteins)-alphaMSH (show POMC Proteins)-induced cortisol production through its antagonistic properties towards MSH (show POMC Proteins) at the level of MC4-R (show MC4R Proteins)

AGRP Protein Profile

Protein Summary

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Alternative names and synonyms associated with AGRP

  • agouti related protein (Agrp)
  • agouti related protein homolog (mouse) (AGRP)
  • agouti related protein homolog (mouse) (Agrp)
  • agouti related protein homolog (mouse)-like (AGRP)
  • agouti related protein-like (LOC100350397)
  • AGRT protein
  • ART protein
  • ASIP2 protein

Protein level used designations for AGRP

agouti-related protein , orexigenic neuropeptide , agouti related protein homolog (mouse) , agouti related protein

11604 Mus musculus
181 Homo sapiens
611198 Canis lupus familiaris
397275 Sus scrofa
443269 Ovis aries
25582 Rattus norvegicus
101804660 Anas platyrhynchos
100732852 Cavia porcellus
280987 Bos taurus
427535 Gallus gallus
782203 Bos taurus
100350397 Oryctolagus cuniculus
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