AGRP Protein (AA 21-132) (His-SUMO Tag)
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- Target See all AGRP Proteins
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-132
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AGRP protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AQMGLAPMEG IRRPDQALLP ELPGLGLRAP LKKTTAEQAE EDLLQEAQAL AEVLDLQDRE PRSSRRCVRL HESCLGQQVP CCDPCATCYC RFFNAFCYCR KLGTAMNPCS RT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product AGRP Protein
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Agouti Related Protein Homolog (Mouse) (AGRP) (AA 21-132) protein (His tag)
AGRP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Agouti Related Protein Homolog (Mouse) (AGRP) protein (His tag)AGRP Origin: Mouse Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
Agouti Related Protein Homolog (Mouse) (AGRP) protein (Fc Tag)AGRP Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Agouti Related Protein Homolog (Mouse) (AGRP) (AA 83-132), (partial) protein (GST tag)AGRP Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Agouti Related Protein Homolog (Mouse) (AGRP) proteinAGRP Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Alternative Name
- AGRP (AGRP Products)
- Synonyms
- AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
- Background
- Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
- Molecular Weight
- 28.5 kDa
- UniProt
- O00253
- Pathways
- Feeding Behaviour, Photoperiodism
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