AGRP Protein (Fc Tag)
-
- Target See all AGRP Proteins
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Protein Type
- Recombinant
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AGRP protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse AgRP/AGRP Protein (Fc Tag)
- Sequence
- Met1-Thr131
- Characteristics
- A DNA sequence encoding the mouse AGRP (Met1-Thr131) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 85 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product AGRP Protein
-
Agouti Related Protein Homolog (Mouse) (AGRP) (AA 21-132) protein (His tag)
AGRP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Agouti Related Protein Homolog (Mouse) (AGRP) protein (His tag)AGRP Origin: Mouse Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
Agouti Related Protein Homolog (Mouse) (AGRP) (AA 83-132) protein (His tag)Crystallography grade AGRP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Agouti Related Protein Homolog (Mouse) (AGRP) (AA 82-131) protein (His tag)Crystallography grade AGRP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Agouti Related Protein Homolog (Mouse) (AGRP) (AA 83-132), (partial) protein (GST tag)AGRP Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- Alternative Name
- AgRP/AGRP (AGRP Products)
- Synonyms
- AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
- Background
-
Background: Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
Synonym: Agrt,Art
- Molecular Weight
- 39.4 kDa
- NCBI Accession
- NP_031453
- Pathways
- Feeding Behaviour, Photoperiodism
-
